G4-PROTAC: targeted degradation of a G-quadruplex binding protein by Patil, Kiran M., Chin, Danielle, Seah, Hui Ling, Shi, Qi, Lim, Kah Wai, Phan, Anh Tuân

“…We report the first use of G4 as warhead of a proteolysis-targeting chimera (G4-PROTAC) for targeted degradation of a G4-binding protein (RHAU/DHX36). …”
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Studies of wafer level electromigration test for ULSI by Sum, Heng Keong.

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Design of insulated gate bipolar transistor using novel structure by Zhang, Guowei

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Proteomic and metabolomic analyses of the human adult myocardium reveal ventricle-specific regulation in end-stage cardiomyopathies by Hunter, B, Li, M, Parker, BL, Koay, YC, Harney, DJ, Pearson, E, Cao, J, Chen, GT, Guneratne, O, Smyth, GK, Larance, M, O’Sullivan, JF, Lal, S

“…Inter-ventricular significance of these metabolic pathways was then found to be diminished within end-stage dilated cardiomyopathy and ischaemic cardiomyopathy, while heart failure-associated pathways were increased in the left ventricle relative to the right within ischaemic cardiomyopathy, such as fluid sheer-stress, increased glutamine-glutamate ratio, and down-regulation of contractile proteins, indicating a left ventricular pathological bias.…”

Large scale paired antibody language models by Kenlay, H, Dreyer, FA, Kovaltsuk, A, Miketa, D, Pires, D, Deane, CM

“…With the advent of next-generation sequencing, billions of antibody sequences have been collected in recent years, though their application in the design of better therapeutics has been constrained by the sheer volume and complexity of the data. To address this challenge, we present IgBert and IgT5, the best performing antibody-specific language models developed to date which can consistently handle both paired and unpaired variable region sequences as input. …”

Battery operated portable fridge by Ng, Chun Kiat.

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Quality over quantity: powering neuroimaging samples in psychiatry by Makowski, C, Nichols, TE, Dale, AM

“…In this review, we encourage this discourse to shift from a focus on sheer increases in sample size to more thoughtful choices surrounding experimental study designs. …”

Regression analysis ofr characterization of materials for photovoltaic cells by Vundavalli, Bala Satya Manikanta

“…The traditional Design-of-Experiments (DoEs) adapted so far, are slow and the information obtained sometimes bears little relevance to optimizing the key performance parameters of merit. …”
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Random by Koh, Bryan Theng Hui, Chan, Melody, Tang, Weixin

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Ancient Art, Modern Tech: Experiencing the Digital Reinvention of the Mogao Grottoes by Zhao, Celina

“…But now it must confront the greatest challenge to its continued existence: modern-day tourism. The sheer volume of visitors seeking a direct experience of this unique but delicate site has resulted in an increasingly rapid process of destruction in the 21st century. …”
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The golden thread of Woolmington – A domestic yarn that should never have been spun by Dyer, Karen

“…The case of Woolmington v The Director of Public Prosecutions [1935] 1 AC 462 is renowned for Viscount Sankey’s ‘golden thread’ ruling, that the prosecution bears the burden of proof at trial. However, what is frequently overlooked is that this judgment arises from domestic violence. …”
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Glycans function as a Golgi export signal to promote the constitutive exocytic trafficking by Sun, Xiuping, Tie, Hieng Chiong, Chen, Bing, Lu, Lei

“…Using a super-resolution microscopy method that we previously developed, we revealed that O-glycan deficient Tac chimeras localize at the interior of the trans-Golgi cisternae. …”
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Seismic performance of tuned liquid damper in novel wall interlocking block by Ong, Peng Pheng

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Engineering modular platforms for rapid vaccine development by Brune, K

“…IMX313 is an engineered chimera of the multimerization domain of chicken complement inhibitor C4-binding protein. …”

Wind tunnel design and fabrication for lift force investigation by Kong, Shao Ming

“…As wind tunnels are resource intensive equipment, its potential as a learning aid is greatly hampered due to the sheer cost and logistics involved in the operation of a full sized wind tunnel. …”
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Ig.n.is. by Ong, Jian'an.

“…This spectrum does not appear suddenly, nor was it by sheer chance. There is a cascading effect on successive development of thought and spirituality that led to where we are, who we are, and why do we behave the way we do.…”
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Aggregating and analyzing Indian political tweets by Chirag Ruhela

“…Understanding this huge data-set in its raw form is not possible due to the sheer dimensionality of the data-set. Thus dimensionality reduction and clever insightful visualizations are needed to make this data consumable for general public. …”
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Developement of electrical equivalent circuit for super capacitor by Muhammad Bukhari Amiruddin.

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Battery reliability balancing by Tan, Yong Quan.

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Thermoelectric refrigerator by Keh, Yao Long.

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