Proteomic and metabolomic analyses of the human adult myocardium reveal ventricle-specific regulation in end-stage cardiomyopathies by Hunter, B, Li, M, Parker, BL, Koay, YC, Harney, DJ, Pearson, E, Cao, J, Chen, GT, Guneratne, O, Smyth, GK, Larance, M, O’Sullivan, JF, Lal, S

“…Inter-ventricular significance of these metabolic pathways was then found to be diminished within end-stage dilated cardiomyopathy and ischaemic cardiomyopathy, while heart failure-associated pathways were increased in the left ventricle relative to the right within ischaemic cardiomyopathy, such as fluid sheer-stress, increased glutamine-glutamate ratio, and down-regulation of contractile proteins, indicating a left ventricular pathological bias.…”

Large scale paired antibody language models by Kenlay, H, Dreyer, FA, Kovaltsuk, A, Miketa, D, Pires, D, Deane, CM

“…With the advent of next-generation sequencing, billions of antibody sequences have been collected in recent years, though their application in the design of better therapeutics has been constrained by the sheer volume and complexity of the data. To address this challenge, we present IgBert and IgT5, the best performing antibody-specific language models developed to date which can consistently handle both paired and unpaired variable region sequences as input. …”

Quality over quantity: powering neuroimaging samples in psychiatry by Makowski, C, Nichols, TE, Dale, AM

“…In this review, we encourage this discourse to shift from a focus on sheer increases in sample size to more thoughtful choices surrounding experimental study designs. …”

Ancient Art, Modern Tech: Experiencing the Digital Reinvention of the Mogao Grottoes by Zhao, Celina

“…But now it must confront the greatest challenge to its continued existence: modern-day tourism. The sheer volume of visitors seeking a direct experience of this unique but delicate site has resulted in an increasingly rapid process of destruction in the 21st century. …”
Get full text
Get full text

Design, synthesis, characterization and property study of topological structures of DNA by Li, Dawei

“…It is demonstrated in the current studies for the first time that the shapes of DNA writher (toroidal and interwound forms) can be precisely created sheerly through maneuvering the sequence of DNA and with no involvement of topological enzymes. …”
Get full text

Wind tunnel design and fabrication for lift force investigation by Kong, Shao Ming

“…As wind tunnels are resource intensive equipment, its potential as a learning aid is greatly hampered due to the sheer cost and logistics involved in the operation of a full sized wind tunnel. …”
Get full text

Ig.n.is. by Ong, Jian'an.

“…This spectrum does not appear suddenly, nor was it by sheer chance. There is a cascading effect on successive development of thought and spirituality that led to where we are, who we are, and why do we behave the way we do.…”
Get full text

Aggregating and analyzing Indian political tweets by Chirag Ruhela

“…Understanding this huge data-set in its raw form is not possible due to the sheer dimensionality of the data-set. Thus dimensionality reduction and clever insightful visualizations are needed to make this data consumable for general public. …”
Get full text

The eagle and the panda : an owl's view from Southeast Asia by Desker, Barry

“…As noted by Singapore's ambassador-at-large Chan Heng Chee, "the U.S. is unlikely to turn its back to problems in the Middle East or on West Asia. …”
Get full text

Material extrusion-based printing optimization of recycled HDPE filaments made from used milk jugs by Teng, Phillis Soek Po, Tee, Chor Hiong, Tan, Hwee Boon, Leong, Kah Fai

“…High-density polyethylene (HDPE) is a widely used thermoplastic material for product packaging. The sheer availability of recyclable or recycled HDPE (rHDPE) from used packaging has led to efforts to apply it in MEX printing. …”
Get full text

Edge/cloud resource management for time-sensitive applications by Lim, Her Huey

“…Technological advancements and skyrocketing interest in areas such as Artificial Intelligence and Internet of Things as well as the sheer increase in development of software solutions, tools, infrastructure, and more have driven demand for cloud resources to staggering heights. …”
Get full text

SyROCCo: enhancing systematic reviews using machine learning by Fang, Z, Arana-Catania, M, van Lier, F-A, Outes Velarde, J, Bregazzi, H, Airoldi, M, Carter, E, Proctor, R

“…The sheer number of research outputs published every year makes systematic reviewing increasingly time- and resource-intensive. …”

HIV decision support : from molecule to man by Sloot, Peter M. A., Coveney, P. V., Muller, V., Boucher, Charles A. B., Ertaylan, Gokhan, Bubak, Marian

“…Effective highly active antiretroviral therapy and the availability of genetic screening of patient virus data have led to sustained viral suppression and higher life expectancy in patients who have been infected with HIV. The sheer complexity of the disease stems from the multiscale and highly dynamic nature of the system under study. …”
Get full text
Get full text

Mental task design based on EEG signal for brain computer interface system. by Tan, Tian Swee, Ngeu @ Yeo, Chee Hau @ Chee Hau, Sheikh, Jahanzeb, Matthias, Tiong Foh Thye, Leong, Kah Meng

Get full text

Classifying vulnerability to sleep deprivation using baseline measures of psychomotor vigilance by Kwoh, Chee Keong, Gooley, Joshua J., Patanaik, Amiya, Chua, Eric C. P., Chee, Michael W. L.

“…Citation: Patanaik A, Kwoh CK, Chua EC, Gooley JJ, Chee MW. Classifying vulnerability to sleep deprivation using baseline measures of psychomotor vigilance. …”
Get full text
Get full text

Dividend study with alternative tests, panel data analysis and panel generalised autoregressive conditional heteroscedasticity by Ng, Chee Pung

Get full text

Business continuity management : towards an operational framework by Ng, Brandon Chee Khoon, Lai, Danny Chee Wai, Hu, Leong Peng

Get full text

Efficient top-k continuous query processing over sliding window model (SWM) method on uncertain data stream by Wahab, Raja Azhan Syah Raja, Rum, Siti Nurulain Mohd, Ibrahim, Hamidah, Ishak, Iskandar

“…As a result of both the sheer amount of data generated and the rate of change, traditional processing methods are in dire need of an upgrade. …”
Get full text

Compensating R&D specialists in Singapore by Chee, Suay Kheong, Hor, Swee Liang, Yeow, Chee Keong

Get full text

Efficient decoding of permutation codes obtained from distance preserving maps by Chee, Yeow Meng, Purkayastha, Punarbasu

Get full text
Get full text