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9161
Biomolecular hydration in protein-protein interaction, protein stability and aggregation and lead optimization : computational studies
Published 2017“…"JAL‟ provides 3 novel utilities that have not yet been reported in other software packages: (1) computation of residence times of waters which are then used to rapidly identify water bridges involving multiple waters (2) rapid computation of buried waters in an explicit solvent MD trajectory using a novel “evaporation” technique and (3) a structure based search to compute the likelihood of favorably displacing interfacial waters; this method contrasts well with other available sophisticated but computationally expensive free energy methods. …”
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Thesis -
9162
新加坡英汉双语儿童对形状量词 “条”、“片”、“粒”的习得研究 = A study of the acquisition of Chinese shape classifiers tiao, pian, li by English-Chinese bilingual children in Singapore...
Published 2018“…本文研究结果能为新加坡华语教育界提供有价值的参考,并为形状量词的习得研究带来新的发现。 There has been much research on children’s acquisition of shape classifiers (e.g. …”
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Final Year Project (FYP) -
9163
会话分析研究 : “like” 在新加坡华语中的语用功能 = Conversation analysis : “like” in Singapore Mandarin conversations
Published 2018“…Through the process of the high frequency usage, there have been extensions in discourse functions of “like” aside from its original semantic meaning. …”
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Final Year Project (FYP) -
9164
范晔《后汉书》“论”、“赞”研究 = Study on Lun and Zan of Fan Ye's History of Eastern Han
Published 2014“…Among Early Four Historiographies, the value of Fan Ye's History of Eastern Han has always been underestimated due to the fact that he was announced to be a rebel. …”
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Final Year Project (FYP) -
9165
Talking careers: using interviews with learner stakeholders to understand the graduate outcome gap. Stakeholder internal report. Autumn 2024.
Published 2024“…Given the critical importance for all learners of securing graduate level work, understanding factors relevant to addressing the graduate outcome gap as identified within the experiences and views of key stakeholders, i.e., of learners of colour, have been neglected in the literature to date. This internal report presents exploratory research designed to help address this area of neglect and to contribute to the relevant evidence base. …”
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Monograph -
9166
Black hole binary formation and mergers in supermassive black hole discs
Published 2024“…<p>Following the first gravitational wave (GW) detection in 2015, there have now been 90+ detections of merging black holes (BHs). …”
Thesis -
9167
Investigating the content and function of stress-induced extracellular vesicles in colorectal cancer
Published 2021“…In CRC, EVs are known to be potent drivers of primary tumour growth and metastasis, and have also been shown to modulate response to treatment by promoting drug resistance. …”
Thesis -
9168
Investigating S-acylation in the metabolic dysfunction of the T2D heart
Published 2023“…The lipid post translational modification <em>S</em>-acylation has been linked to regulating CD36 trafficking. However, it remains unknown whether CD36 is <em>S</em>-acylated in the heart and whether CD36 <em>S</em>-acylation levels are altered in T2D.…”
Thesis -
9169
Boronic acid and nitrofuranyl derivatives as potential therapeutics
Published 2021“…‘Rule of 5’, there has been extensive research on lead-like compounds other than those in the realm of small molecule drug-likeness. …”
Thesis -
9170
Seroprevalence of SARS-CoV-2 in children and adolescents
Published 2023“…Seroprevalence studies evaluating population prevalence of SARS-CoV-2 antibodies have an important role in understanding the spread of and population vulnerability to SARS-CoV-2 infection. Most have been performed in adults, and those in children have predominantly tested samples obtained opportunistically in a clinical context or in school-based populations, both of which bring potential biases.…”
Thesis -
9171
Production and characterization of collagen and gelatin from edible jellyfish (Acromitus hardenbergi Stiasny, 1934) for fabrication of biofunctional scaffold
Published 2014“…Jellyfish have always been an important fishery commodity and a multi-million business widely practised in China, Japan, Malaysia, Indonesia, Thailand, Vietnam and the Philippines. …”
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Thesis -
9172
Structure and functions of a metallo-beta-lactamase- like hypothetical protein bleg1_2437 from alkali-tolerant soil bacterium Bacillus lehensis G1
Published 2015“…In the present study, there are 1202 hypothetical proteins (HPs) have been discovered from newly sequenced genome of alkali-tolerant soil bacterium B. lehensis G1, HP Bleg1_2437 may likely be an MBL. …”
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Thesis -
9173
Purification of miraculin from miracle fruit [Synsepalum dulcifium (Schumach. & Thonn.) Daniell]
Published 2015“…However, optimization of efficient purification method of miraculin from miracle fruit has not been reported in the literature. Immobilized metal ion affinity chromatography (IMAC) with nickel-NTA was employed for miraculin purification from the extract of the pulp with optimization. …”
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Thesis -
9174
Development and validation of questionnaire on knowledge, attitudes, practices and perceived barriers related to nutrition care process among clinical dietitians in Malaysia
Published 2015“…To date, no questionnaire has been developed and validated to assess the KAPB on the NCP. …”
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Thesis -
9175
Antimicrobial susceptibility and molecular profiles of acinetobacter baumannii in Makkah hospitals, and the potential use of bacteriophage as a treatment option
Published 2022“…There are increasing trends of resistance to agents that been reserved to treat carbapenem-resistant A. baumannii i.e. tigecycline and colistin. …”
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Thesis -
9176
Factors associated with body weight status and internet addiction among malaysian university students in Penang: mixed method study before and during covid-19 pandemic
Published 2024“…In this study, it has been demonstrated that severely internet addiction students have inappropriate dietary behaviour and poor diet quality. …”
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Thesis -
9177
Storage and eruption of silicic magma across the transition from dominantly effusive to caldera-forming states at an arc volcano (Santorini, Greece)
Published 2019“…Processes driving crystallization appear to have been similar in the two systems, despite the differences of scale. …”
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Journal Article -
9178
Discrete time optimal control and its applications in power systems
Published 2020“…A closed-form mathematical derivation for the DTOC algorithm was fi rst proposed by Han, which has been widely used to design estimators, observers and noise-tolerant differentiators. …”
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Thesis-Doctor of Philosophy -
9179
Synthesis of epoxidized poly(ester carbonate)-b-polyimide-b-poly(ester carbonate) : reactive single-walled carbon nanotube dispersants enable synergistic reinforcement around multi...
Published 2020“…PI block copolymer systems containing reactive poly(ester carbonate)s have not yet been reported and are expected to act as effective reactive dispersing agents of SWNTs. …”
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Journal Article -
9180
Role of N-WASP in cell proliferation : implication for organ development and cancer
Published 2020“…Development of organs such as lungs and mammary glands requires elongation and branching of epithelial tissues which are critically depended on apical-basal polarity, cell adhesion, cell proliferation and interactions with the extracellular matrix proteins. N-WASP has also been shown to regulate cell invasion and EMT (Epithelial to Mesenchymal transition), which are often upregulated during cancer progression. …”
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Thesis-Doctor of Philosophy