Desymmetrisation of 1,3-diols and their diacetates under enzymatic heterogeneous catalysis and synthesis of 1,3-diols under continuous flow conditions by Pamarthy, Varsha Siri

“…Piperidones are present in many biologically important compounds. One of the key steps in the synthesis of one such piperidone, N-benzyl-5- methoxypiperidone, is the desymmetrisation of 1,3-diol, N-Benzyl-5-hydroxy-4- (hydroxymethyl)pentanamide or 1,3-diacetate, N-Benzyl-5-acetoxy-4- (acetoxymethyl)pentanamide, which provide access to the (R)- and (S)- enantiomers of the piperidone, respectively. …”
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Design, characterization and properties of nitrogen-containing novel organic N-type materials by Wu, Yuechao.

“…Although a lot of n-type organic materials have been reported,this research will specially focus on N-substituted polycyclic aromatic hydrocarbons(PAHs)because Houk et al predicted that the azaacenes have high electron affinities and could be promising candidates for n-type semiconducting materials.In fact,some N-heteroacenes have already shown decent electron mobility.Moreover,N-heteroacenes are more stable(resistive to oxidation or dimerization).In addition,the physical properties of n-substituted heteroacenes strongly depend on the number,position and valence states of nitrogen atoms.These progresses strongly encourage me to prepare larger azaacenes In this thesis,I have designed,synthesized and characterized several new azaacenes,which are expected to exhibit good performance in electronic devices.I developed a simple and efficient method(one or two steps)to prepare targeted azaacenes through condensation reaction starting from commercially available materials.All as-prepared compounds are very stable and have lower bandgaps.Phototransistors based on 6,8,15,17-tetraaza-1.18,4.5,9.10,13.14- tetrabenzoheptacene(TTP)single crystals have been fabricated and this device exhibited excellent performance in amplifying and converting light signal under the photoconductive effect.In addition,9,11,13,22,24,26-hexaza-tetrabenzo[a,c,l,n]heptacene(HATBH)can act as an efficient anion sensor for naked-eye detection of F- and H2PO4- anions and 9,26-dihydro 9,11,13,22,24,26-hexaza-tetrapyrido[3,2-a: 2’,3’-c:3”,2”-l:2”’,3”’-n]heptacene(DHATPH)can selectively sense F- anion among TEN anions(F-,Cl-,Br -,I-,PF6-,HSO4-,NO3-,BF4-,AcO-,and H2PO4-). …”
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Gene expression regulation by well-known non-coding RNAs by Tan, Jiazi

“…In this thesis, I studied the functions of two well-known non-coding ribonucleic acids (ncRNAs), namely U1 small nuclear ribonucleic acid (snRNA) and Xist, which exert their influence over gene expression via different pathways. 5’ splice site (5’ss) recognition by U1 snRNA binding is one of the first steps in pre-mRNA splicing, which is critical for gene expression in eukaryotes. …”
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On strong semismoothness and superlinear convergence of complementarity problems over homogeneous cones by Nguyen, Hai Ha

“…Meng, and divide the method into four steps. The next parts of Chapter 2 discuss the application of the method for adjusting the strong semismoothness of projection onto second-order cones, then give a couple of counter examples to see the important things we need to notice when doing this method. …”
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Development of immune-modulatory RNAS to regulate RIG-I-like receptors mediated antiviral immune response for therapy and vaccination by Yong, Hui Yee

“…A spontaneously formed VLP from both MS2 and Q beta were obtained after several purification steps and was confirmed via negative staining Electron microscopy. …”
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Development and characterisation of novel silicon pixel detectors for tracking and timing by Gaži, M

“…</p> <p>Furthermore, this thesis outlines a preliminary investigation of improved clustering methods that use Time-of-Arrival information to enhance the spatial resolution of the MALTA2 sample by ∼20% and improve the timing resolution by ∼7%. Further steps for generalisation of the method are also discussed.…”

A behaviour-based analytical malware detection framework for android smartphones by Damshenas, Mohsen

“…We hope this research can be a stepping stone for improvement in Android malware detection techniques and development of safe Android markets which eventually increase the security of end-user devices.…”
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Physical unclonable function based solutions to unification of user, device and data authentication by Zheng, Yue

“…At a time of rampant public media manipulation and ease of fake image/video fabrication, verification of benign and malicious image transformations is necessary but not sufficient for fact checking of visual artefacts presented in the court of law. …”
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USER RESEARCH WITH KIDS : HOW TO EFFECTIVELY CONDUCT RESEARCH WITH PARTICIPANTS AGED 3-16 / by Snitker, Thomas Visby, author 642961

Optimizing OOD Detection in Molecular Graphs: A Novel Approach with Diffusion Models by Shen, Xu, Wang, Yili, Zhou, Kaixiong, Pan, Shirui, Wang, Xin

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Interpretable Computational Modeling of pre-mRNA Splicing for Multiple Eukaryotic Species by McCue, Kayla M.

“…One of the key steps in eukaryotic gene expression is pre-mRNA splicing, whereby intronic sequences are excised from immature pre-mRNA transcripts and the remaining exonic sequences are joined together. …”
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Probabilistic and Analytic Methods in Combinatorics by Sawhney, Mehtaab

“…The fifth chapter provides bounds for online vector balancing by finding a Markov chain on R with integer steps and for which the stationary distribution is Gaussian. …”
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Application of in vitro erythropoiesis from bone marrow derived progenitors to detect and study genotoxicity by Shuga, Joseph F. (Joseph Francis)

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3D model reconstruction of damaged parts in an automated remanufacturing process using additive manufacturing technology by Aprilia

“…For widespread acceptance of “automation of remanufacturing process”, all steps should be carried out automatically by software with no human interaction except for the final verification. …”
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Multimodal fusion for navigation of autonomous mobile robots using a deep learning method by Lee, Anthony Wen Hao

“…Subsequently the policy will return outputs on the future states of the differential-drive robots for its next time steps. Experiments is then executed, and the results of the proposed method will be compared to the original method for holonomic robots. …”
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Design, development and analysis of a full carbon fibre reinforced composite chassis of an electric vehicle by Khoo, Raymond Rui Xiang

“…The advantages, limitations and complexity to perform such simulations will be evaluated to formulate a realistic achievable vehicle structure development targets and steps in this report. Methods to simplify complex dynamic load problems into equivalent quasi-static load will also be explored to speed up development process. …”
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Global response of Vibrio cholerae to predation by heterotrophic protists by Hu, Jie

“…These findings will serve as a stepping-stone for further detailed understanding of the interactions between V. cholerae and protozoa, which in turn will lead to a better understanding of how pathogenic bacteria evolve in the environment.…”
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Chiral spin textures in a frustrated kondo lattice model by Munir Shahzad

“…The rise in temperature smooths out the steps in Hall conductivity making longitudinal conductivity non-zero over the whole range of Fermi energy. …”
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Identification of offshore wind turbine foundation properties from monitoring data by Anderson, EF

“…</p> <br> <p>In successfully estimating the properties of two foundation models from simulated data, and tackling various complications that arise in the process, this work provides the first steps into a new area of research on the identification of OWT foundation properties from monitoring data.…”

Immune Checkpoint Blockade sensitivity and Progression-Free Survival associates with baseline CD8+ T cell clone size and cytotoxicity by Watson, R, Tong, O, Taylor, C, Kumar Sharma, P, Verge De Los Aires, A, Mahe, E, Ruffieux, H, Nassiri, I, Middleton, M, Fairfax, B

“…The cells contained within the expression matrices and Seurat objects have undergone full pre-processing and QC steps and are used for the analysis and figures in the linked manuscript. …”