Instrumenting Observability in a Decentralized Microservice Architecture by Liu, Helen X.

“…The integrated system created here satisfies our system’s requirements of a consolidated observability platform while also enabling future customizations, thereby allowing problems to be identified more quickly and proactively.…”
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Inosine-containing mRNA induces an innate immune response and is translated with lower efficiency by Bao, Caroline

“…ADAR editing activity is known to play a key role in modulating the host cell’s immune response to RNA. Here, we specifically study the effect of the presence of inosine in RNA by generating an inosine-containing reporter mRNA sequence. …”
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Multiplicative resonant enhancement of chemical detection by Ma, Wenchao, Pestourie, Raphaël, Lin, Zin, Aguirre-Soto, Alan, Sikes, Hadley D., Johnson, Steven G.

“…Optical resonances can increase the sensitivity of measurements to material perturbations and also accelerate photochemical reactions. Here, we show that these two effects can be combined multiplicatively, to enhance the detection via weak or low-concentration photochemical reactions far beyond what could previously be attained. …”
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Materials beyond monolayers: The magnetic quasi-1D semiconductor CrSBr by Klein, Julian, Ross, Frances M.

“…Fortunately, new layered materials are on the horizon that preserve their useful properties even when thicker than a monolayer. Here, we summarize our interest in one of these emergent materials, the magnetic semiconductor CrSBr. …”
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Gelation, clustering, and crowding in the electrical double layer of ionic liquids by Goodwin, Zachary AH, McEldrew, Michael, Pedro de Souza, J, Bazant, Martin Z, Kornyshev, Alexei A

“…B 125, 2677 (2021)] developed a theory for reversible ion associations in bulk ILs, which accounted for the formation of all possible (Cayley tree) clusters and a percolating ionic network (gel). Here, we adopt and develop this approach to understand the associations of ILs in the electrical double layer at electrified interfaces. …”
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Improvements to Quantum Interior Point Method for Linear Optimization by Mohammadisiahroudi, Mohammadhossein, Wu, Zeguan, Augustino, Brandon, Carr, Arielle, Terlaky, Tam?s

“…However, this method requires a large number of gates and qubits to be implemented. Here, we propose a new IF-QIPM using the normal equation system, which requires less number of gates and qubits. …”
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Dual-phase microporous polymer nanofilms by interfacial polymerization for ultrafast molecular separation by Lee, Tae Hoon, Balcik, Marcel, Wu, Wan-Ni, Pinnau, Ingo, Smith, Zachary P

“…Fine-tuning microporosity in polymers with a scalable method has great potential for energy-efficient molecular separations. Here, we report a dual-phase molecular engineering approach to prepare microporous polymer nanofilms through interfacial polymerization. …”
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Characterizing the Impact of Oligomerization on Redox Flow Cell Performance by Weiss, Trent A, Fan, Gang, Neyhouse, Bertrand J, Moore, Evan B, Furst, Ariel, Brushett, Fikile R

“…Redox‐active oligomers (RAOs) have recently been proposed for mitigating this phenomenon while maintaining sufficient transport properties; however, to date, few studies have quantified how the chemical and electrochemical properties of RAOs influence their performance in redox flow cells. Here, we demonstrate that oligomeric derivatives of 2,2,6,6‐tetramethylpiperidine 1‐oxyl (TEMPO) exhibit lower diffusivities than the monomeric species but retain facile charge transfer characteristics. …”
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Dataset Design for Building Models of Chemical Reactivity by Raghavan, Priyanka, Haas, Brittany C, Ruos, Madeline E, Schleinitz, Jules, Doyle, Abigail G, Reisman, Sarah E, Sigman, Matthew S, Coley, Connor W

“…Perhaps the most determining factor is the composition of the training data and whether it is sufficient to train a model that can make accurate predictions over the full domain of interest. Here, we discuss the design of reaction datasets in ways that are conducive to data-driven modeling, emphasizing the idea that training set diversity and model generalizability rely on the choice of molecular or reaction representation. …”
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Hypersonic heat transfer and anisotropic visualization with a higher order discontinuous Galerkin finite element method by Quattrochi, Douglas J. (Douglas John)

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A role for polyamine regulators in ESC self-renewal by Zhao, Tianyun, Goh, Kim Jee, Ng, Huck Hui, Vardy, Leah A.

“…The polyamines spermine and spermidine are essential for a wide range of biological processes, and their levels are tightly regulated. Here, we review the polyamine pathway and discuss how it can impact polyamine levels, cellular methylation and hypusinated EIF5A levels. …”
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Collaborative querying through a hybrid query clustering approach by Goh, Dion Hoe-Lian, Fu, Lin, Foo, Schubert, Na, Jin-Cheon

“…Harnessing previously issued queries to facilitate collaborative querying is an approach that can help users in digital libraries and other information systems better meet their information needs. Here, the kernel step is to identify and cluster similar queries by mining the query logs. …”
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Engineering protein thermostability using a generic activity-independent biophysical screen inside the cell by Asial, Ignacio, Cheng, Yue Xiang, Engman, Henrik, Dollhopf, Maria, Wu, Binghuang, Nordlund, Pär, Cornvik, Tobias

“…Unfortunately, identifying stabilizing mutations is not trivial since most are neutral or deleterious. Here we describe a high-throughput colony-based stability screen, which is a direct and biophysical read-out of intrinsic protein stability in contrast to traditional indirect activity-based methods. …”
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Synthesis and telomeric G-quadruplex-stabilizing ability of macrocyclic hexaoxazoles bearing three side chains by Ma, Yue, Iida, Keisuke, Sasaki, Shogo, Hirokawa, Takatsugu, Heddi, Brahim, Nagasawa, Kazuo, Phan, Anh Tuân

“…G-quadruplexes (G4s), which are structures formed in guanine-rich regions of DNA, are involved in a variety of significant biological functions, and therefore “sequence-dependent” selective G4-stabilizing agents are required as tools to investigate and modulate these functions. Here, we describe the synthesis of a new series of macrocyclic hexaoxazole-type G4 ligand (6OTD) bearing three side chains. …”
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A multimodal approach to analysis of steady state visually evoked potentials by Vij, Nikhil, Zuobin, Wu, Bjornsdotter, Malin, Dauwels, Justin, Vialatte, François-Benoît

“…Steady state visually evoked potentials (SSVEPs), recorded from the central nervous system of humans using electroencephalography (EEG) in response to visual stimuli, have recently gained attention in cognitive and clinical neuroscience [1]. Here, we fuse EEG SSVEPs with recordings from functional magnetic resonance imaging data (fMRI) utilizing the millisecond temporal resolution of the former and the excellent spatial resolution of the latter. …”
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Dielectric metamaterials with toroidal dipolar response by Economou, Eleftherios N., Soukoulis, Costas M., Fedotov, Vassili A., Savinov, Vassili, Zheludev, Nikolay I., Basharin, Alexey A., Kafesaki, Maria

“…Toroidal multipoles are the terms missing in the standard multipole expansion; they are usually overlooked due to their relatively weak coupling to the electromagnetic fields. Here, we propose and theoretically study all-dielectric metamaterials of a special class that represent a simple electromagnetic system supporting toroidal dipolar excitations in the THz part of the spectrum. …”
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Graphite oxide to graphene. Biomaterials to bionics by Thompson, Brianna Clair, Murray, Eoin, Wallace, Gordon G.

“…The rich chemistries available are able to ensure properties uncovered in the nanodomain are conveyed into the world of macroscopic devices. Here, the inherent properties of graphene, along with how graphene or structures containing it interface with living cells and the effect of electrical stimulation on nerves and cells, are reviewed.…”
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Influence of no-core fiber on the focusing performance of an ultra-small gradient-index fiber probe by Bi, Shubo, Wang, Chi, Zhu, Jun, Yuan, Zhiwen, Yu, Yingjie, Valyukh, Sergiy, Asundi, Anand

“…For the parameters of the fiber probe studied here, the effective beam expansion length of the no-core fiber spacer is less than 0.357 mm.…”
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MMP14 in sarcoma : a regulator of tumor microenvironment communication in connective tissues by Gonzalez-Molina, Jordi, Gramolelli, Silvia, Liao, Zehuan, Carlson, Joseph W., Ojala, Päivi M., Lehti, Kaisa

“…Thus, a comprehensive understanding of the biology of MMP14 in sarcomas will shed light on the mechanisms controlling the key processes in these diseases. Here, we provide an overview of the function and regulation of MMP14 and we discuss their relationship with clinical and pre-clinical MMP14 data in both adult and childhood sarcomas.…”
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Effect of oblique retroreflection from a vibrating mirror on laser Doppler shift by Agusanto, Kusuma, Lau, Gih-Keong, Liu, Ting, Zhu, Chuangui

“…However, the reading of LDV obtained from the recovered signal is not right because the retroreflection adds extra Doppler frequency shifts to the oblique reflection. Here, we first derive the relationship of Doppler shift to the oblique angle of retroreflection. …”
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