Collective synthesis of 4-Hydroxy-2-pyridone alkaloids and their antiproliferation activities by Ding, Feiqing, Leow, Min Li, Ma, Jimei, William, Ronny, Liao, Hongze, Liu, Xue-Wei

“…A collective synthesis of 4-hydroxy-2-pyridone alkaloids—specifically, pretenellin B, prebassianin B, farinosone A, militarione D, pyridovericin, and torrubiellone C—has been achieved. Key steps include using a strategic convergent method to synthesize the densely substituted pyridone key intermediate by Suzuki–Miyaura cross-coupling reaction, a divergent synthesis approach of target molecules by aldol condensation of pyridone intermediate with homologous aldehydes, and an iterative synthesis of homologous aldehydes with all-trans-polyene backbones. …”
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Short-term load forecasting by wavelet transform and evolutionary extreme learning machine by Li, Song, Wang, Peng, Goel, Lalit

“…Compared to the conventional neuro-evolution method, ELM-MABC can improve the learning accuracy with fewer iteration steps. The proposed method is tested on two datasets: ISO New England data and North American electric utility data. …”
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Recalled parental bonding interacts with oxytocin receptor gene polymorphism in modulating anxiety and avoidance in adult relationships by Cataldo, Ilaria, Bonassi, Andrea, Lepri, Bruno, Foo, Jia Nee, Setoh, Peipei, Esposito, Gianluca

“…Implications for clinical work and future steps are described in the Conclusion.…”
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Quantum sensing of radio-frequency signal with NV centers in SiC by Jiang, Zhengzhi, Cai, Hongbing, Cernansky, Robert, Liu, Xiaogang, Gao, Weibo

“…These results pave the first steps for silicon carbide quantum sensors toward low-cost nuclear magnetic resonance spectrometers with a wide range of practical applications in medical, chemical, and biological analysis.…”
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The Body and the Brain: Measuring Skin Conductance Responses to Understand the Emotional Experience by Christopoulos, Georgios I., Uy, Marilyn Ang, Yap, Wei Jie

“…Importantly, we describe in detail a specific research protocol (fear conditioning) that serves as an illustrative example to support the initial steps for organizational scholars who are new to the method. …”
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Effects of phorbol ester on vesicle dynamics as revealed by total internal reflection fluorescence microscopy by Zhang, Enming, Xue, Renhao, Soo, Jianchow, Chen, Peng

“…As mainly revealed indirectly by the electrophysiological methods, exocytosis is believed to involve multiple kinetic steps in which vesicles transit from one state to another. …”
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SPH modeling of solitary wave fissions over uneven bottoms by Li, Jing, Liu, Huaxing, Gong, Kai, Tan, Soon Keat, Shao, Songdong

“…A series of numerical experiments of solitary wave propagating over different bottom geometries are then conducted, which include the waves over a mild shelf or underwater steps with varied amplitude-depth ratios. The fission processes of both non-breaking and breaking solitary waves are discussed, numerical results of the free surface profiles and amplitude of the solitons show reasonable agreements with that of RANS model, as well as available experimental data. …”
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Towards an optimal and unbiased approach for tumor cell isolation by Sajay, Bhuvanendran Nair Gourikutty, Chang, Chia-Pin, Ahmad, Hamizah, Chung, Wong Chee, Puiu, Poenar Daniel, Rahman, Abdur Rub Abdur

“…We present a negative enrichment approach, integrating WBC depletion and chemical-free RBC depletion in the same setup without the need for centrifugation, washing or multiple sample handling steps. This approach achieves an average of >90 % recovery of spiked tumor cells and >99 % total WBC depletion in whole blood across multiple cell lines, in a simple and easy-to-use assay. …”
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Influence of CEO characteristics and audit committee on financial performance: evidence from Iraq by Hazzaa, Omar Turki, Abdullah, Dewi Fariha, Mohammed Sadaa, Abdullah

“…Three models were used to analyze the data, and the preferred model was chosen by following several confirmation steps. The findings indicated that CEO education, CEO ownership, and CEO experience all influenced financial success. …”
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Multigrid computation of high-speed turbulent flows in ducts by Ding, Zhongman

“…The numerical method used is based on an explicit five-stage Runge-Kutta time-stepping scheme. Multigrid technique and implicit residual smoothing strategy are employed to ensure a high computing efficiency and convergent rate. …”
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The effectiveness of freight derivatives in managing a ship-operator's systematic and unsystematic risks by Tan, Ivy Lay Hui.

“…The methodology, findings and implications are summarized in this report, which may provide the stepping stone for further studies into the commercial application of risk management, and increase the significance of academic research in the business of shipping.…”
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Imbalanced data learning for biomedical application by Xie, Vincent JianHan.

“…This project aims to present a series of steps, starting from the processing of ECG data to the classification of patients using various input features. …”
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Transmission line matrix modelling of microwave circuits and structures by Gosling, Ian Gilbert.

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Automated detection and segmentation of vertebral bodies in volumetric abdominal magnetic resonance images by Lin, Dehui.

“…Detection and segmentation of the column of vertebral bodies are intermediate steps required to identify the bone marrow which is considered as the wrongly labeled visceral adipose tissue in the assessment of abdominal obesity. …”
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Development of multimedia educational software by Saw, Thant Lwin Tun.

“…The results can be shown in detailed steps and in graphical presentations. While this educational software was developed by using Visual Basic programming, graphical presentations and 3D images were drawn by using Autodesk Revit and were exported to Visual Basic as image files for creation of animations.…”
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An assessment of solar power contribution to electric vehicle by Luo, Chuan.

“…The optimized real-time charging scheme will make use of the predicted solar irradiation, expected future EV energy demand and demand-based tariff to design a cheapest real-time charging plan at battery swapping stations. Base on all the steps mentioned above, a comprehensive comparison between the cost of investment on employing Photovoltaic System in swapping stations and the revenue earned by the system will be studied.…”
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NH3 gas detection with graphene field effect transistors by Tay, Jason Zhi Wei.

“…Although the device had been fabricated, the student had learnt the theoretical process steps from his mentor. The student grew graphene using thermal chemical vapour deposition, transferring and characterization of the grown graphene. …”
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Purification of perna viridis (Asian green mussels) adhesive proteins by Lee, Hendrik Jie Hao

“…These processes will have to be environmentally friendly, and be competitive both economically and functionally.1 This report will cover on the steps and methods used to characterise and isolate pure adhesive proteins from the Perna viridis foot glands, which includes gel-electrophoresis (Acid-Urea), high performance liquid chromatography (HPLC), spectrometry (MALDI-TOF), and fractionation of the proteins by precipitation with different water miscible organic solvents.…”
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Tower crane design using product family approach by Lim, Kendrik Yan Hong

“…This report presents the steps taken by the author to develop a new concept model that is aimed at solving the lengthy process via a 3-stage methodology that includes the understanding the traditional modelling methods as well as the utilization of a product family modular-based design and limited production. …”
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Accessibility of immersive 360 videos on mobile devices by Miao, Ziyan

“…This report documents the experimental results, the considerations when creating the App and environment, as well as the steps in implementing Stereoscopic 360o videos and spatial 3D audio in Unity 3D to develop the immersive environment. …”
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