Activated Metals to Generate Heat for Biomedical Applications by Remlova, Eva, Feig, Vivian Rachel, Kang, Ziliang, Patel, Ashka, Ballinger, Ian, Ginzburg, Anna, Kuosmanen, Johannes, Fabian, Niora, Ishida, Keiko, Jenkins, Joshua, Hayward, Alison, Traverso, Giovanni

“…Delivering heat in vivo could enhance a wide range of biomedical therapeutic and diagnostic technologies, including long-term drug delivery devices and cancer treatments. To date, providing thermal energy is highly power-intensive, rendering it oftentimes inaccessible outside of clinical settings. …”
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Narrowing the gap between machine learning scoring functions and free energy perturbation using augmented data by Valsson, Í, Warren, MT, Deane, CM, Magarkar, A, Morris, GM, Biggin, PC

“…However, current models lack robust evaluation and fail on tasks encountered in (hit-to-) lead optimisation, such as ranking the binding affinity of a congeneric series of ligands, thereby limiting their application in drug discovery. Here, we address these issues by first introducing a novel attention-based graph neural network model called AEV-PLIG (atomic environment vector–protein ligand interaction graph). …”

Integrate Traditional Chinese Medicine (TCM) into cognitive behavioural therapy to treat postpartum depression in Chinese culture contexts. by Han, Shuyu.

“…Furthermore, women are expected to provide breastfeed after delivery. Taking drugs such as antidepressants will be strongly believed it’s harmful to child. …”
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Alzheimer’s Amyloid Hypothesis and Antibody Therapy: Melting Glaciers? by Høilund-Carlsen, Poul F., Alavi, Abass, Castellani, Rudolph J., Neve, Rachael L., Perry, George, Revheim, Mona-Elisabeth, Barrio, Jorge R.

“…Two antibodies, aducanumab and lecanemab, have been approved by the U.S. Food and Drug Administration, while a third, donanemab, is under review. …”
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Functionalized microwell laser sorting method for single-cell viable microbial detection by Wang, Y, Xue, Y, Hong, X, Wang, H, Zhou, C, Wang, W, Sheng, J, Liang, P, Li, H, Xu, Q, Wang, Y, Liu, K, Shang, L, Peng, H, Chen, F, Zhang, K, Yin, H, Wang, Y, Deng, F, Feng, S, Huang, WE, Li, B

“…In this study, we introduced a laser-induced forward transfer (LIFT) with functionalized microwell arrays, called functionalized microwell laser sorting (FMLS). …”

Experiences, perceptions and ethical considerations of the malaria infection study in Thailand by Naemiratch, B, Kulpijit, N, Ruangkajorn, S, Day, NPJ, Prachumsri, J, Cheah, PY

“…Methods: This paper drew from ethics and social science qualitative study called MIST-ETHICS embedded within the MIST studies. …”

Establishment and optimization of induced pluripotent stem cell technologies by Amir Morshedi

“…This finding has had tremendous impact on drug discovery and disease modeling and there is great hope for these cells to replenish body cells for therapy. …”
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Evaluation of diabetic wound healing properties of moringa oleifera lam using in vitro and in vivo wound models by Muhammad Amali, Abubakar

“…Therefore, may serve as a lead in drug discovery for diabetic wound healing.…”
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Single-molecule diagnostics to support curative interventions for tuberculosis and HIV by Dougan, Tyler J.

“…HIV can be treated with lifelong medication. But if drug resistance develops or treatment is interrupted, the virus resurges. …”
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Cryo-electron microscopy structure of the Mycobacterium tuberculosis cytochrome bcc:aa₃ supercomplex and a novel inhibitor targeting subunit cytochrome cI by Mathiyazakan, Vikneswaran, Wong, Chui Fann, Harikishore, Amaravadhi, Pethe, Kevin, Grüber, Gerhard

“…Thus, the bcc:aa3 complex represents a valid drug target for Mycobacterium tuberculosis infections. …”
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Malaria parasite stress tolerance is regulated by DNMT2-mediated tRNA cytosine methylation by Hammam, Elie, Sinha, Ameya, Baumgarten, Sebastian, Nardella, Flore, Liang, Jiaqi, Miled, Samia, Bonhomme, Frédéric, Erdmann, Diane, Arcangioli, Benoit, Arimondo, Paola B., Dedon, Peter, Preiser, Peter, Scherf, Artur

“…Our findings give insight into a novel molecular mechanism that regulates P. falciparum response to drug treatment and sexual commitment.…”
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You Are the Placebo : Making Your Mind Matter / by Dispenza, Joe, author 656175, Hay House (Online service) 656169

“…Is it possible to heal by thought alone—without drugs or surgery? The truth is that it happens more often than you might expect. …”
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Effect of inflammation on apolipoprotein A-1(apoA-1) secretion by intestinal cells. by Yu, Kenneth.

“…This study has shown that ApoA-l secretion in intestinal cells is constitutive; however, the rate of apoA-l secretion is increased by as high as 5-times the constitutive secretion rate when the cells are exposed to anti-inflammatory drugs such as aspirin and paracetamol. In contrast, pro-inflammatory drugs such as lipopolysaccharides and endotoxin appeared to decrease intestinal secretion of apoA-1. …”
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Poisson vector graphics (PVG) by Hou, Fei, Sun, Qian, Fang, Zheng, Liu, Yong-Jin, Hu, Shi-Min, Qin, Hong, Hao, Aimin, He, Ying

“…Armed with two new types of primitives, called Poisson curves and Poisson regions, PVG can easily produce photorealistic effects such as specular highlights, core shadows, translucency and halos. …”
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Please, let me go / by Spencer, Caitlin, author 656310, Brown, Linda Watson author 656311

“…From the age of 14, Caitlin was completely controlled, repeatedly raped, provided with alcohol, given drugs, sold and passed on to new gangs over and over again. …”

Neutron emission studies from miniature and medium size plasma focus device by Singh, Rajdeep Raweet.

“…Although dense plasma focus devices have attracted the attention of scientific community since 1960’s as a copious source of fusion neutrons but in the recent years owing to spin-off in the applications of compact and portable table top neutron sources in wider domain, like noninvasive interrogation of explosives and narcotic drugs (by using Pulsed Fast/Thermal Neutron Analysis (PFTNA) technique), dark matter research, radioisotope production, medical neutron therapy and soil humidity measurements, there has been renewed interest across the globe for the development of sub-kilojoule range, low energy small plasma focus device (hereafter called ‘Miniature Plasma Focus i.e. …”
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Rationale and concerns for using JAK inhibitors in axial spondyloarthritis by Ahmed, S, Yesudian, R, Ubaide, H, Coates, LC

“…Treatment options have advanced over recent years and have become more targeted, including biologic treatments and, more recently, small molecule oral drugs called Janus kinase inhibitors. These newer agents have a rapid onset of action, can be taken orally and have efficacy in reducing inflammation across the whole spectrum of disease. …”

Arabic botany and pharmacology with particular reference to the work of Al-Zahrawi and Ibn Juljul in Muslim Spain by Johnstone, PC

“…They were moreover interested in local indigenous plant names - in the language which they called Latīnī or ^cajamiyat al-Andalus.</p>…”

Low-power processors for implantable epileptic seizure detection system by Baihaqi, Muhammad Rayhan

“…Despite several treatments are available to suppress the seizure such as anti-epileptic drugs and surgery, around 25% of the epileptic patients still experiences the seizure. …”
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Animal models of human disease 2.0 by Lange, Sigrun, Inal, Jameel

“…This Special Topic "Animal Models of Human Disease 2.0", called for state-of-the-art primary research and review articles, inviting global experts conducting fundamental and translational research in comparative animal models of human diseases. …”
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