Protein delivery options: how well have we succeeded? by Ng, Xu Wen, Subbu, Venkatraman

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Changes in microbial and physicochemical properties during free-cell and encapsulated probiotic fermentation of red dragon fruit juice by Ong, Yien Yien

“…Fermentation of red dragon fruit juice with free cell and microencapsulated probiotic showed no adverse effect on the physico-chemical characteristics especially the antioxidant properties of,red dragon fruit juice. …”
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Glass box and black box machine learning approaches to exploit compositional descriptors of molecules in drug discovery and aid the medicinal chemist by Robson, B, Cooper, R

“…The synthetic medicinal chemist plays a vital role in drug discovery. Today there are AI tools to guide next syntheses, but many are “Black Boxes” (BB). …”

Formulation and in-vitro release study of drug loaded liposomes for treating dry eye disease by Chua, Yan Ni

“…In addition, such drug delivery system have been proven to provide numerous pharmaceutical benefits such as protecting the drugs within its bilayer as well as providing a sustained release of drugs. …”
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Liposomal encapsulation of pro-NO donor drug by Koh, Cheryl Jie Yan

“…Liposomes are utilised as drug carrier due to its biocompatibility and inert nature in the physiological body, to protect the drug as well as prevent premature elimination by the body. …”
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Targeting the cytochrome oxidases for drug development in mycobacteria by Lee, Bei Shi, Sviriaeva, Ekaterina, Pethe, Kevin

“…In this review, we are discussing current knowledge about the two mycobacterial aerobic respiratory branches, their potential as drug targets, as well as potential drawbacks.…”
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Recent advances in the development of liquid crystalline nanoparticles as drug delivery systems by Leu, Jassica S. L., Teoh, Jasy J. X., Ling, Angel L. Q., Chong, Joey, Loo, Yan Shan, Mat Azmi, Intan Diana, Zahid, Noor Idayu, Bose, Rajendran J. C., Madheswaran, Thiagarajan

“…In addition, the composition of mesophases can be modified by pore diameters, thus influencing drug release. Much research has been conducted in recent years to improve their preparation and characterization, as well as to control drug release and improve the efficacy of loaded bioactive chemicals. …”
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Prolonged release of risperidone via gastro retentive drug delivery device by Kwan, Audrey Kai Xin

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Millifluidic synthesis of amorphous drug-polysaccharide nanoparticle complex with tunable size intended for supersaturating drug delivery applications by Tran, The-Thien, Nguyen, Minh-Hiep, Tan, Yong Zen, Chew, Jia Wei, Khan, Saif A., Hadinoto, Kunn

“…The conventional bulk mixing method to prepare amorphous drug-polysaccharide nanoparticle complex (or drug nanoplex in short) has a major drawback in the lack of size control for the nanoplex produced, hence limiting its potential applications as a supersaturating drug delivery system for bioavailability enhancement of poorly soluble drugs. …”
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Emergence of spatio-temporal variations in chemotherapeutic drug efficacy : in-vitro and in-silico 3D tumour spheroid studies by Sheraton, Muniraj Vivek, Chiew, Geraldine Giap Ying, Melnikov, Valentin, Tan, E. Y., Luo, K. Q., Verma, N., Sloot, Peter M. A.

“…A mechanistic drug-cell interaction model was developed and simulated to analyse the localized efficacy of these drugs. …”
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A rapid CRISPR competitive assay for in vitro and in vivo discovery of potential drug targets affecting the hematopoietic system by Shen, Yunbing, Jiang, Long, Iyer, Vaishnavi Srinivasan, Raposo, Bruno, Dubnovitsky, Anatoly, Boddul, Sanjaykumar V., Kasza, Zsolt, Wermeling, Fredrik

“…In conclusion, we present a rapid experimental approach to identify potential drug targets related to mature immune cells, as well as normal and malignant hematopoiesis.…”
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Exploring drug consumption rooms as ‘inclusion health interventions’: policy implications for Europe by Scher, BD, Chrisinger, BW, Humphreys, DK, Shorter, GW

“…People who use drugs are among the most socially excluded groups in Europe. …”

Layer-by-layer assembled micro and nano carriers for drug delivery applications by Mutukumaraswamy Shaillender

“…In nano- or microparticulate drug delivery, both control of the drug release and interaction of the particles with the cellular environment are critical attributes. …”
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Fabrication of micro-needles for transdermal drug delivery by Ng, Hui Beng

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Studies of injectable in situ depot-forming systems for drug delivery by Liu, Hui

“…Polymer solution undergoes phase inversion when injected into an aqueous solution and forms depots in situ, with the drug trapped inside released over time. Several parameters were studied to understand their effects on the drug release dynamics, including polymer hydrophobicity and Mw, drug type and solvent type. …”
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Large simple randomized controlled trials—from drugs to medical devices: lessons from recent experience by Buccheri, S, James, S, Mafham, M, Landray, M, Melvin, T, Oldgren, J, Bulbulia, R, Bowman, L, Hoogervorst, LA, de Mheen, PJM, Juni, P, McCulloch, P, Fraser, AG

“…They are considered essential to establish definitive evidence of efficacy and safety for new drugs, and whenever possible they should also be the preferred method for investigating new high-risk medical devices. …”

An iGlu receptor antagonist and its simultaneous use with an anticancer drug for cancer therapy by Luo, Zhong, Li, Peizhou, Tan, Si Yu, Ang, Chung Yen, Nguyen, Kim Truc, Zhao, Yanli

“…The present work demonstrated the feasibility of employing a delivery system to deliver both neuroprotective drug and anticancer drug for efficient anticancer treatment.…”
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Critical test of the beneficial consequences of lifting the ban on direct-to-consumer advertising for prescription drugs in Italy: experimental exposure and questionnaire study by Schulz, Peter Johannes, Crosignani, Francesca, Petrocchi, Serena

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Evaluation of paper spray mass spectrometry for direct analysis of small molecule drugs and hemoglobin constant spring peptide markers by Takyi-Williams, John

“…The studies described in this thesis were undertaken to evaluate the application of paper spray mass spectrometry for direct analysis of small molecule drugs and biomarker in dried matrix spot samples. …”
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Development of biomimetic 3D cancer platform for drug testing by Ker, Sia Fong

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