Pharmacological PPARβ/δ activation upregulates VLDLR in hepatocytes by Zarei, Mohammad, Barroso, Emma, Palomer, Xavier, Escolà-Gil, Joan Carles, Cedó, Lidia, Wahli, Walter, Vázquez-Carrera, Manuel

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In silico screening of sugar alcohol compounds to inhibit viral matrix protein VP40 of Ebola virus by Nagarajan, Nagasundaram, Yapp, Edward Kien Yee, Le, Nguyen Quoc Khanh, Yeh, Hui-Yuan

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Examining patient choice and provider competition under the National Health Insurance Fund outpatient cover in Kenya: does it enhance access and quality of care? by Kazungu, J, Barasa, E, Quaife, M, Nonvignon, J

“…Most providers ensured the availability of drugs, provided a wider range of services and leveraged on marketing to attract and retain NHIF members. …”

Phaleria macrocarpa fruit protein aqueous extract affects viral entry, virucidal activity, and progeny release by Ismaeel, Mahmud Yusef Yusef, Chee, Wai Yip, Norefrina Shafinaz Md Nor, Nazlina Ibrahim

“…PMFPAE displayed antiviral activity towards all the HHV-1 strains when post-treated with high selective indices (SIs) of 80.6, 50, and 35, respectively. …”
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Synthesis, Characterisation Of Stilbene–Arylcinnamide Hybrids And Cytotoxic Studies Against Lung Cancer Cell A549 by Mohd Zaki, Nurain Syazwani

“…In this study, a total of 24 compounds of a new hybrid series has been designed and synthesised, resulting from the coupling of stilbene and arylcinnamide scaffolds. All synthesised stilbene-arylcinnamide hybrids were obtained in 42-80% yield. …”
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1,3,5-triazaspiro[5.5]undeca-2,4-dienes as selective Mycobacterium tuberculosis dihydrofolate reductase inhibitors with potent whole cell activity by Yang, Xuan, Wedajo, Wassihun, Yamada, Yoshiyuki, Dahlroth, Sue-Li, Neo, Jason Jun-Long, Dick, Thomas, Chui, Wai-Keung

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Detection of low frequency artemisinin resistance mutations, C469Y, P553L and A675V, and fixed antifolate resistance mutations in asymptomatic primary school children in Kenya by Osoti, V, Wamae, K, Ndwiga, L, Gichuki, PM, Okoyo, C, Kepha, S, Keitany, K, Kandie, R, Aricha, S, Kiplagat, R, Mwandawiro, C, Bejon, P, Snow, RW, Ochola-Oyier, LI

“…Background: To understand the emergence and spread of drug-resistant parasites in malaria-endemic areas, accurate assessment and monitoring of antimalarial drug resistance markers is critical. …”

An analysis of heavy silicone oil treatment for inferior proliferative vitreoretinopathy by Hammer, M, Ie, A, Eibenberger, K, Auffarth, GU, Xue, K

“…The number of glaucoma drugs were increased in 45% of patients during Densiron tamponade. …”

Protein Folding, Host Cell Proteostasis, and Viral Evolution by Yoon, Jimin

“…Interestingly, virtually all RNA viruses rely on their host’s proteostasis network components for viral protein folding. …”
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The potential of fluocinolone acetonide to mitigate inflammation and lipid accumulation in 2D and 3D foam cell cultures by Nguyen, Luong T. H., Muktabar, Aristo, Tang, Jinkai, Wong, Yee Shan, Thaxton, Colby S., Venkatraman, Subbu Subramanian, Ng, Kee Woei

“…Inflammation plays an important role in all stages of atherosclerosis development. Therefore, the use of anti-inflammatory drugs could reduce the risk of major adverse cardiovascular events due to atherosclerosis. …”
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Treatment of acute sore throat in Malaysia: a consensus of multidisciplinary recommendations using modified Delphi methodology by Abdullah, Baharudin, Koh, Kar Chai, Mohamed, Mohazmi, Tan, Vincent Eng Soon, Mohammad, Nurashikin, Sekawi, Zamberi, Periyasamy, Petrick, Ramadas, Anitha, Duerden, Martin

“…A consensus was reached if at least 70% of the group agreed with the statement. Results: All 10 statements for managing acute sore throat achieved consensus. …”
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Biointerface design for vertical nanoprobes by Elnathan, Roey, Barbato, Maria Grazia, Guo, Xiangfu, Mariano, Anna, Wang, Zixun, Santoro, Francesca, Shi, Peng, Voelcker, Nicolas H., Xie, Xi, Young, Jennifer L., Zhao, Yunlong, Zhao, Wenting, Chiappini, Ciro

“…Vertical nanoprobes have substantially improved our ability to control and characterize the intracellular environment, guide biophysical stimuli with nanoscale precision to defined cell compartments, stimulate and record the electrical activity of cells, and transport hard-to-deliver drugs. These capabilities are enabling substantial advances in bioelectronics, spatiotemporally resolved molecular diagnostics, and cell and gene therapy — all underpinned by the design versatility of the nanoprobe biointerface. …”
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Structural and mechanistic studies of herpes virus proteins by Patel, Vidhi Kanaiyalal

“…Herpes Simplex Viruses (HSV) 1 and 2 are the most prevalent amongst the eight known human herpes viruses (HHV). All herpes viruses have a characteristic life cycle, divided into latent and lytic phases. …”
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Utilizing food waste and thermoplastic starch (TPS) in 3D printed PLA formulations for sustainable and customizable controlled delivery systems by Wang, Liwen

“…With the addition of TPS, the drug release profile can be adjusted from 8 – 120 hours using different TPS ratios and different printed wall thicknesses. …”
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Gametocyte carriage in uncomplicated plasmodium falciparum malaria following treatment with artemisinin combination therapy: a systematic review and meta-analysis of individual pat... by Abdulla, S, Achan, J, Yeka, A, D'Alessandro, U, Adam, I, Alemayehu, B, Allan, R, Temu, E, Allen, E, Barnes, K, Anvikar, A, Valecha, N, Arinaitwe, E, Ashley, E, Carrara, V, McGready, R, Nosten, F, Lee, S, White, N, Asih, P, Awab, G, Dondorp, A, Fanello, C, Woodrow, C, Dahal, P, Guerin, P, Humphreys, G, Moreira, C, Nsanzabana, C, Price, R, Sibley, C, Stepniewska, K, Bassat, Q, Gonzalez, R, Baudin, E, Checchi, F, Espie, E, Grandesso, F, Nabasumba, C, Schramm, B, Björkman, A, Bompart, F, Lameyre, V, Bonnet, M, Borrmann, S, Bousema, T, Cenci, F, Cot, M, Faucher, J, Kapulu, M, Marsh, K, Mayxay, M, Newton, P, Roper, C, Deloron, P, Djimde, A, Fofana, B, Doumbo, O, Sagara, I, Dorsey, G, Rosenthal, P, Drakeley, C

“…The gametocytocidal properties of antimalarial drugs are important for malaria elimination efforts. …”

Duration of carbapenemase-producing enterobacteriaceae carriage in hospital patients by Mo, Yin, Hernandez-Koutoucheva, Anastasia, Musicha, Patrick, Bertrand, Denis, Lye, David C., Ng, Oon Tek, Fenlon, Shannon N., Chen, Swaine L., Ling, Moi Lin, Tang, Wen Ying, Barkham, Timothy, Nagarajan, Niranjan, Cooper, Ben S., Marimuthu, Kalisvar

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Inorganic nanoparticles–driven self–assembly of natural small molecules in water for constructing multifunctional nanocapsules against plant diseases by Liu, Li-Wei, Ding, Zheng-Hao, Ren, Gang-Gang, Wang, Guang-Di, Pan, Xin, Wei, Guo-Hai, Zhou, Xiang, Wu, Zhi-Bing, Jin, Zhi-Chao, Chi, Robin Yonggui, Yang, Song

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The combined activation of KCa3.1 and inhibition of Kv11.1/hERG1 currents contribute to overcome Cisplatin resistance in colorectal cancer cells by Pillozzi, Serena, D'Amico, Massimo, Bartoli, Gianluca, Gasparoli, Luca, Petroni, Giulia, Crociani, Olivia, Marzo, Tiziano, Guerriero, Angela, Messori, Luigi, Severi, Mirko, Udisti, Roberto, Wulff, Heike, Chandy, Kanianthara George, Becchetti, Andrea, Arcangeli, Annarosa

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Maximizing dissimilarity in resting state detects heterogeneous subtypes in healthy population associated with high substance use and problems in antisocial personality by Kashyap, Rajan, Bhattacharjee, Sagarika, Yeo, Thomas B. T., Chen, Annabel Shen-Hsing

“…Here, we use an alternative way to extract the rs-fMRI features that are common across all the scans by applying common-and-orthogonal-basis-extraction (COBE) technique. …”
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Efficacy and safety of tirzepatide for treatment of overweight or obesity. A systematic review and meta-analysis by Tan, Bryan, Pan, Xin-Hui, Chew, Jocelyn Han Shi, Goh, Rachel Sze Jen, Lin, Chaoxing, Anand, Vickram Vijay, Lee, Ethan Cheng Zhe, Chan, Kai En, Kong, Gwyneth, Ong, Christen En Ya, Chung, Charlotte Hui, Young, Dan Yock, Chan, Mark Y., Khoo, Chin Meng, Mehta, Anurag, Muthiah, Mark Dhinesh, Noureddin, Mazen, Ng, Cheng Han, Chew, Nicholas W. S., Chin, Yip Han

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