Cardiocutaneous syndrome is caused by aggregation of iASPP mutants by Lotz, R, Osterburg, C, Schäfer, B, Lu, X, Dötsch, V

“…In contrast to these germline mutations causing cardiocutaneous syndromes, missense mutations found in cancer do not result in aggregation.…”

Electrochemical DNA-nano biosensor for the detection of cervical cancer-causing HPV-16 using ultrasmall Fe₃O₄-Au core-shell nanoparticles by Rasouli, Elisa, Basirun, Wan Jefrey, Johan, Mohd Rafie, Rezayi, Majid, Mahmoudian, Mohammad Reza, Poenar, Daniel Puiu

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Cause-Specific Excess Mortality During the COVID-19 Pandemic (2020–2021) in 12 Countries of the C-MOR Consortium by Beeks, Victoria V., Achilleos, Souzana, Quattrocchi, Annalisa, Pallari, Chryso T., Critselis, Elena, Salameh, Pascale, Rahmanian Haghighi, Mohammad R., Rodriguez-Llanes, Jose M., Ambrosio, Giuseppe, Artemiou, Andreas, Gabel, John, Bennett, Catherine M., Cuthbertson, Joseph, Zimmermann, Claudia

“…Methods We collected weekly cause-specific mortality data from respiratory disease, pneumonia, cardiovascular disease (CVD) and cancer from national vital statistic databases. …”
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Indirect effects of the COVID-19 pandemic: A cause-of-death analysis of life expectancy changes in 24 countries, 2015 to 2022 by Polizzi, A, Zhang, L, Timonin, S, Gupta, A, Dowd, JB, Leon, DA, Aburto, JM

“…Most countries saw small changes in suicide mortality during the pandemic, while alcohol mortality increased and cancer mortality continued to decline. Patterns for other causes were more variable. …”

Global burden of 288 causes of death and life expectancy decomposition in 204 countries and territories and 811 subnational locations, 1990–2021: a systematic analysis for the Glob... by Naghavi, M, Ong, KL, Aali, A, Almidani, O, Bandyopadhyay, S, Basnyat, B, Maude, R, Dolecek, C, Lacey, BWH

“…The analysis used 56 604 data sources, including data from vital registration and verbal autopsy as well as surveys, censuses, surveillance systems, and cancer registries, among others. As with previous GBD rounds, cause-specific death rates for most causes were estimated using the Cause of Death Ensemble model—a modelling tool developed for GBD to assess the out-of-sample predictive validity of different statistical models and covariate permutations and combine those results to produce cause-specific mortality estimates—with alternative strategies adapted to model causes with insufficient data, substantial changes in reporting over the study period, or unusual epidemiology. …”

Knowledge on gastric cancer, attitude on screening for gastric cancer and screening behavior of gastric cancer among out patients in Hospital Universiti Sains Malaysia by Saffai, Siti Norzietai

“…Gastric cancer is heterogenous or multifactorial disease which is it affects the human physical and psychosocial well-being and leading cause of morbidity, mortality, economic burden in both developed and developing countries. …”
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Targeted therapy to gastric cancer by Hou, Qian.

“…Gastric cancer is a leading cause of death in Asia and a heterogeneous disease. …”
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Novel device for microwave cancer detection by Goh, Chye Ying.

“…Breast cancer is one of the leading causes of cancer deaths among women and early detection leads to earlier treatment and improve survival rates. …”
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Functional genetics of cancer and congenital disorders by Zak, J

“…This thesis aims to identify and assess pathogenic mutations in the 1q41q42 microdeletion syndrome, neural tube defects, neuropsychiatric disorders and cancer. Rare microdeletions at the 1q41q42 locus cause a clinically heterogeneous syndrome characterized by developmental delay, characteristic dysmorphic features and brain morphological abnormalities. …”

Pan-cancer analysis of whole genomes by ICGC/TCGA Pan-Cancer Analysis of Whole Genomes Consortium

“…A collection of papers from the PCAWG Consortium describes non-coding mutations that drive cancer beyond those in the TERT promoter; identifies new signatures of mutational processes that cause base substitutions, small insertions and deletions and structural variation; analyses timings and patterns of tumour evolution; describes the diverse transcriptional consequences of somatic mutation on splicing, expression levels, fusion genes and promoter activity; and evaluates a range of more-specialized features of cancer genomes.…”

Probiotic extracellular vesicles engineering for colorectal cancer by Tan, Jing Ren

“…Colorectal cancer (CRC) has been one of the leading causes for cancer-related deaths globally. …”
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The involvement of hypoxia in APOBEC-mediated mutagenesis in multiple cancers by Liang, J

“…<p>Mutational signatures have been studied to associate mutations to their originating causes. One such signature is that of the APOBEC family of proteins. …”

Breast cancer susceptibility : accessing newly discovered SNPs by Loh, Eunice Ting Wei

“…Breast cancer susceptibility has been found to exhibit familial aggregation, caused by underlying genetic factors contributing to its risks. …”
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Investigating the effects of IGFs on immune responses in prostate cancer by Kim, J

“…RNA sequencing of the tumours revealed inflammatory and senescence-associated secretory phenotype (SASP)-like signatures, suggesting cellular stress caused by the IGF axis blockade. In conclusion, IGF axis contributes to remodelling of prostate cancer TIME, with species-dependent changes in immune cell repertoire. …”

BRCA1 regulation of breast cancer cell motility by Hernandez Nuñez, ZE

“…<p>Breast cancer remains a leading cause of cancer-related mortality globally, generating a need for a deeper understanding of the molecular mechanisms driving its progression. …”

Determination of octreotide acetate as radiosensitizer in breast cancer cell lines by Alkhansa, Salih Mahmoud Abdalla

“…Breast cancer is a common type of cancer that affects women worldwide and causes death related to cancer. …”
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Injectable cell transplantation system for cytokine-based cancer immunotherapy by Gerard Nathanael Adrianus.

“…Cancer is a major killing disease, causing 6.7 million deaths globally in 2002. …”
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Gut microbiota in colorectal cancer: biological role and therapeutic opportunities by Pandey, Himani, Tang, Daryl W. T., Wong, Sunny Hei, Lal, Devi

“…Colorectal cancer (CRC) is the second-leading cause of cancer-related deaths worldwide. …”
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Contribution of metabolic alterations to genome instability and its association with cancer development by Woo, Ren He

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Preventing delayed diagnosis of cancer: clinicians’ views on main problems and solutions by Car, Lorainne Tudor, Papachristou, Nikolaos, Urch, Catherine, Majeed, Azeem, El–Khatib, Mona, Aylin, Paul, Atun, Rifat, Car, Josip, Vincent, Charles

“…Methods We developed and implemented a new priority–setting approach called PRIORITIZE and invited North West London cancer care clinicians to identify and prioritize main causes for and solutions to delayed diagnosis of cancer care. …”
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