Changes in cerebrospinal fluid balance of TNF and TNF receptors in naïve multiple sclerosis patients : early involvement in compartmentalised intrathecal inflammation by Magliozzi, Roberta, Pezzini, Francesco, Pucci, Mairi, Rossi, Stefania, Facchiano, Francesco, Marastoni, Damiano, Montagnana, Martina, Lippi, Giuseppe, Reynolds, Richard, Calabrese, Massimiliano

“…CSF levels of TNFR1 were associated with cortical lesion volume (r = 0.41) at T0, as well as with new cortical lesions (r = 0.56), whilst no correlation could be found between TNFR2 levels in CSF and clinical or MRI features. …”
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Electrode modification by diazonium chemistry : studies on the effect of steric bulk on film thickness, and modified activated carbon cloths for energy storage by Subrata, Arnold

“…Of the multiple methods which exist for this purpose, aryldiazonium cation reduction is widely considered to be the most popular, due to the high stability of the grafted layer on the surface, as well as the relative ease of the modification procedure. …”
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Public bus transit service modeling and optimization: from conventional to autonomous vehicles by Tian, Qingyun

“…Public transit is a cost-efficient and sustainable travel mode because of its huge capacity. A well-designed transit network can not only reduce the operation costs of operators but also reduce the travel time of passengers. …”
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Cryogelation of human hair keratins by Chua, Huei Min

“…The emergence of HHK in biomedical applications is attributed to their proven biocompatibility as well as their potential to promote cell adhesion and proliferation due to the presence of LDV (leucine-aspartic-valine) cell adhesion motifs and residual regulatory molecules. …”
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MCMC inversion of the transient and steady-state creep flow law parameters of dunite under dry and wet conditions by Masuti, Sagar, Barbot, Sylvain

“…The mechanical properties of olivine at steady state are well constrained. However, the physical mechanism underlying transient creep, an evolutionary, hardening phase converging to steady state asymptotically, is still poorly understood. …”
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Increased consumption of unsaturated fatty acids improves body composition in a hypercholesterolemic Chinese population by Haldar, Sumanto, Ponnalagu, Shalini, Osman, Farhana, Tay, Shia Lyn, Wong, Long Hui, Jiang, Yuan Rong, Leow, Melvin Khee-Shing, Henry, Christiani Jeyakumar

“…Despite increases in mean daily intakes of total energy (approximately +400 kcal/day, female, and approximately +240 kcal/day, male), as well as increases in percentage of calories from fats and proteins and decreases in percentage of calories from carbohydrates during the dietary intervention period, there were no significant changes in total body fat mass in both genders and also in all treatment groups. …”
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Automated segmentation of visceral, deep subcutaneous, and superficial subcutaneous adipose tissue volumes in MRI of neonates and young children by Kway, Yeshe Manuel, Thirumurugan, Kashthuri, Tint, Mya Thway, Michael, Navin, Shek, Lynette Pei-Chi, Yap, Fabian Kok Peng, Tan, Kok Hian, Godfrey, Keith M., Chong, Yap Seng, Fortier, Marielle Valerie, Marx, Ute C., Eriksson, Johan G., Lee, Yung Seng, Velan, S. Sendhil, Feng, Mengling, Sadananthan, Suresh Anand

“…The model generalized well to different body sizes and ages and to all abdominal levels. …”
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MCI-frcnn: a deep learning method for topological micro-domain boundary detection by Tian, Simon Zhongyuan, Yin, Pengfei, Jing, Kai, Yang, Yang, Xu, Yewen, Huang, Guangyu, Ning, Duo, Fullwood, Melissa Jane, Zheng, Meizhen

“…At the training phase in MCI-frcnn, 50 images of RAIDs from Drosophila RNAPII ChIA-Drop data, containing 261 micro-RAIDs with ground truth boundaries, were trained for 7 days. Using this well-trained MCI-frcnn, we detected micro-RAID boundaries for the input new images, with a fast speed (5.26 fps), high recognition accuracy (AUROC = 0.85, mAP = 0.69), and high boundary region quantification (genomic IoU = 76%). …”
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Robust incentive mechanisms for efficient and secure coded edge intelligence by Ng, Jer Shyuan

“…In consideration of the heterogeneity of the edge nodes, i.e., computational and communication capabilities as well as storage capacities, I propose incentive mechanism designs to encourage the edge nodes to facilitate the CDC tasks over the distributed edge computing networks. …”
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Directing the architecture of surface-clean Cu₂O for CO electroreduction by Liu, Jiawei, You, Futian, He, Bowen, Wu, Yinglong, Wang, Dongdong, Zhou, Weiqiang, Qian, Cheng, Yang, Guangbao, Liu, Guofeng, Wang, Hou, Guo, Yi, Gu, Long, Feng, Lili, Li, Shuzhou, Zhao, Yanli

“…The high catalytic activity of the BCF that results from the clean surface and the coexistence of Cu(100) and Cu(110) in the lattice is well-supported by density functional theory calculations. …”
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Exploring the perceptions of mhealth interventions for the prevention of common mental disorders in university students in Singapore: qualitative study by Salamanca-Sanabria, Alicia, Jabir, Ahmad Ishqi, Lin, Xiaowen, Alattas, Aishah, Kocaballi, A. Baki, Lee, Jimmy, Kowatsch, Tobias, Car, Lorainne Tudor

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Error measurements for a quantum annealer using the one-dimensional Ising model with twisted boundaries by Chancellor, Nicholas, Crowley, Philip J. D., Durić, Tanja, Vinci, Walter, Amin, Mohammad H., Green, Andrew G., Warburton, Paul A., Aeppli, Gabriel

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Nontoxic, biodegradable hyperbranched poly(β-amino ester)s for efficient siRNA delivery and gene silencing by Ooi, Ying Jie, Huang, Chongquan, Lau, Kieran, Chew, Sing Yian, Park, Jong Gu, Chan-Park, Mary B.

“…This provides valuable insight into the future development of safe and efficient non-viral siRNA delivery systems as well as their translation into clinical applications.…”
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Current frailty knowledge, awareness, and practices among physicians following the 2022 European consensus document on Frailty in Cardiology by Wong, Jie Jun, Wang, Laureen Yi-Ting, Hasegawa, Koji, Ho, Kay Woon, Huang, Zijuan, Teo, Louis L. Y., Tan, Jack Wei Chieh, Kasahara, Kazuyuki, Tan, Ru-San, Ge, Junbo, Koh, Angela S.

“…P = 0.0002), exercise programmes (well aware, 12.9% vs. 6.0%, adj. P = 0.001), and engaged more in multidisciplinary team care (frequently or occasionally, 52.6% vs. 41%, adj. …”
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Biaxial strain induced OH engineer for accelerating alkaline hydrogen evolution by Zhang, Tao, Ye, Qitong, Han, Zengyu, Liu, Qingyi, Liu, Yipu, Wu, Dongshuang, Fan, Hong Jin

“…The challenge that has yet well resolved is to control the water adsorption and dissociation. …”
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BSACI guidance for the implementation of Palforzia® peanut oral immunotherapy in the United Kingdom: a Delphi consensus study by Marrs, Tom, Patel, Nandinee, Burrell, Sarah, Rampersad, Anjali, Minshall, Eleanor, Leech, Susan, Chandratilleke, Dinusha, Dempsey, Justine, Ludman, Sian, Roberts, Graham, Michaelis, Louise Jane, Brough, Helen A., Karanam, Surendra, Batt, Rebecca, Moulsdale, Phoebe, Steifel, Gary, Tiwana, Kiran, Smith, Helen, Knight, Katherine, Vazquez-Ortiz, Marta, Vyas, Deepan, Turner, Paul J., Makwana, Nick

“…Conclusions: This consensus highlights the urgent need for the NHS to increase capacity for undertaking diagnostic food challenges as well as developing Palforzia® immunotherapy pathways. …”
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The novel quinoline derivative SKA-346 as a KCa3.1 channel selective activator by Wong, Brandon Han Siang, Shim, Heesung, Goay, Stephanie Shee Min, Ong, Seow Theng, Nur Ayuni Binte Muhammad Taib, Chai, Kelila Xin Ye, Lim, Kerry, Huang, Dachuan, Ong, Choon Kiat, Vaiyapuri, Thamil Selvan, Cheah, Yeong Cheng, Wang, Yulan, Wulff, Heike, Webster, Richard David, Shelat, Vishalkumar G., Verma, Navin Kumar

“…In silico analysis using RosettaLigand and GLIDE demonstrated a well-converged pose of SKA-346 in a binding pocket at the interface between the calmodulin N-lobe and the S45A helix in the S4-S5 linker of the KCa3.1 channel. …”
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Harnessing full-text publications for deep insights into C. elegans and Drosophila biomaps by Arulprakasam, Karthick Raja, Toh, Janelle Wing Shan, Foo, Herman, Kumar, Mani R., Kutevska, An-Nikol, Davey, Emilia Emmanuelle, Mutwil, Marek, Thibault, Guillaume

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New multi-target based therapeutics against an opportunistic superbug by Premkumar, Jayaraman.

“…The stereo-electronic properties such as HOMO, LUMO and MEP maps of the hybrid compounds calculated using quantum chemical methods, correlate well with identified common pharmacophoric features required for the multi-site interactions. …”
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Design methodologies for complexity reduction of FIR filters by Faust, Mathias

“…New methods for the optimization of the MCM as well as SA blocks are proposed. First of all, a platform for design automation of FIR filters is introduced with enhanced features added onto this tool for result generation and functional verification. …”
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