A systematic review and network meta-analysis of randomized controlled trials on choice of central venous access device for delivery of chemotherapy by Yeow, Marcus, Soh, Shauna, Yap, Ryan, Tay, Desiree, Low, Yi Fen, Goh, Serene Si Ning, Yeo, Charleen Shanwen, Lo, Joseph Zhiwen

“…A systematic review and network meta-analysis was conducted to compare the safety, quality of life, and cost-effectiveness of different types of central venous access devices (CVADs) for patients receiving chemotherapy.…”
Get full text

Inflammatory and clinical prognostic factors for asthma attacks: a patient-level meta-analysis of control arms of 22 randomised trials by Meulmeester, FL, Mailhot-Larouche, S, Celis-Preciado, C, Lemaire-Paquette, S, Ramakrishnan, S, Wechsler, ME, Brusselle, G, Hardy, J, Diver, SE, Brightling, CE, Castro, M, Hanania, NA, Jackson, DJ, Martin, N, Laugerud, A, Santoro, E, Compton, C, Hardin, ME, Holweg, CTJ, Subhashini, A, Hinks, T, Beasley, RW, Sont, JK, Steyerberg, EW, Pavord, ID, Couillard, S

Effective dietary interventions during pregnancy: a systematic review and meta-analysis of behavior change techniques to promote healthy eating by O’Connor, H, Meloncelli, N, Wilkinson, SA, Scott, AM, Vincze, L, Rushton, A, Dawson, S, Hollis, J, Whiteoak, B, Gauci, S, de Jersey, S

“…The primary aims of this systematic review and meta-analysis were to summarise the effectiveness of dietary interventions for pregnant woman, identify which behaviour change techniques (BCTs) and intervention features were most frequently used and determine which were most effective at improving dietary intake. …”

Association of nucleoside reverse transcriptase inhibitors with adverse perinatal outcomes in pregnant women living with HIV: systematic review and meta-analysis by Cowdell, I, Beck, K, Hey, M, Portwood, C, Sexton, H, Kumarendran, M, Brandon, Z, Kirtley, S, Hemelaar, J

“…</p> <br> <p><strong>Methods of data synthesis:</strong> Random-effects meta-analysis.</p> <br> <p><strong>Results:</strong> 22 cohort studies including 124,478 WLHIV met the eligibility criteria. …”

Perinatal outcomes among pregnant women living with HIV initiating antiretroviral therapy preconception and antenatally: systematic review and meta-analysis by Boering, P, Murray, C, Portwood, C, Hey, M, Thompson, L, Beck, K, Cowdell, I, Sexton, H, Kumarendran, M, Brandon, Z, Kirtley, S, Hemelaar, J

“…Data were analysed using random effects meta-analyses. Quality assessments, subgroup and sensitivity analyses were conducted. …”

Association between self-reported napping and risk of cardiovascular disease and all-cause mortality: a meta-analysis of cohort studies by Wang, Meng, Xiang, Xin, Zhao, Zhengyan, Liu, Yu, Cao, Yang, Guo, Weiwei, Hou, Linlin, Jiang, Qiuhuan

“…Objectives This meta-analysis aims to assess the association between adult nap duration and risk of all-cause mortality and cardiovascular diseases (CVD). …”
Get full text

Meta-Heuristic Search Based Test Data Generation Method for Dynamic-Functional Testing in Automatic Programming Assessment (S/O 13793) by Romli, Rohaida, Abd Wahab, Alawiyah, Romli, Rusnida, Yusoff, Nooraini

“…Recently in software testing research, the adoption of any Meta-Heuristic Search Techniques (MHSTs) has successfully been proven to improve the efficiency of generating adequate and optimal test data. …”
Get full text

Efficacy and safety of rapid-acting insulin analogs in special populations with Type 1 Diabetes or Gestational Diabetes: systematic review and meta-analysis by Nørgaard, Kirsten, Sukumar, Nithya, Rafnsson, Snorri Bjorn, Saravanan, Ponnusamy

“…Methods: PubMed, EMBASE and Cochrane Reviews were searched electronically, and their bibliographies examined to identify suitable studies for review and inclusion in a meta-analysis. Eligible studies were randomized controlled trials that reported data on relevant clinical outcomes. …”
Get full text

The relationship between viral clearance rates and disease progression in early symptomatic COVID-19: a systematic review and meta-regression analysis by Singh, S, Boyd, S, Schilling, WHK, Watson, JA, Mukaka, M, White, NJ

“…The relationship between the clinical and virological treatment effects was assessed by mixed-effects meta-regression.</p> <p><strong>Results:&nbsp;</strong>From 57 potentially eligible RCTs, VCRRs were derived for 44 (52 384 participants); 32 had &ge;1 clinical endpoint in each arm. …”

Diagnostic accuracy of point-of-care lung ultrasound for community-acquired pneumonia in children in ambulatory settings: a systematic review and meta-analysis by Hughes-Davies, H, Ukwatte, U, Roberts, N, Turner, PJ, Hayward, GN, Fanshawe, TR, Bird, C

“…The majority of included studies lacked clarity on training for the index test with potential bias around flow and timing of testing. Meta-analysis of the combined results of the included six studies calculated a pooled sensitivity of 90.9% (95% CI [85.5%, 94.4%]) and pooled specificity of 80.7% (95% CI [63.6%, 91.0%]).…”

Association of current Schistosoma mansoni, Schistosoma japonicum, and Schistosoma mekongi infection status and intensity with periportal fibrosis: a systematic review and meta-analysis by Ewuzie, A, Wilburn, L, Thakrar, DB, Cheng, H, Reitzug, F, Roberts, N, Malouf, R, Chami, GF

“…We screened 1826 titles and abstracts to find 282 articles that met our inclusion criteria for full-text review. 41 studies were eligible for systematic review, 33 studies were eligible for infection status meta-analysis, and seven studies were eligible for infection intensity meta-analysis. …”

Effectiveness of fludrocortisone plus hydrocortisone versus hydrocortisone alone in septic shock: a systematic review and network meta-analysis of randomized controlled trials by Teja, B, Berube, M, Pereira, TV, Law, AC, Schanock, C, Pang, B, Wunsch, H, Walkey, AJ, Bosch, NA

“…<p><strong> Methods: </strong></p> A systematic review and a Bayesian network meta-analysis of peer-reviewed randomized trials were conducted. …”

Longitudinal patterns in smoking abstinence in trials of e-cigarettes for smoking cessation: secondary analysis of data from a systematic review, with meta-analyses by Hartmann-Boyce, J, Chan, J, Zhitnik, E, Pesola, F, Hajek, P, Lindson, N

“…We narratively synthesized data and conducted meta-analyses. <p><strong> Results</p></strong> We included 15 studies (n = 7233 participants). …”

Systematic review and meta-analysis of isolated posterior fossa malformations on prenatal ultrasound imaging (part 1): nomenclature, diagnostic accuracy and associated anomalies by D'Antonio, F, Khalil, A, Garel, C, Pilu, G, Rizzo, G, Lerman-Sagie, T, Bhide, A, Thilaganathan, B, Manzoli, L, Papageorghiou, AT

“…Quality assessment of the included studies was performed using the Newcastle–Ottawa Scale for cohort studies. We used meta-analyses of proportions to combine data and fixed- or random-effects models according to the heterogeneity of the results. …”

Lying and rumination time as predictors of subclinical ketosis, metritis, and hypocalcaemia in dairy cows during the periparturient period: A systematic review and meta-analysis by Sadiq, Mohammed B., Zaini, Syamira-Syazuana, Shaik Mossadeq, Wan Mastura, Ramanoon, Siti Zubaidah, Syed-Hussain, Sharifah Salmah

“…Each disease was subjected to meta-analysis, with the LT and RT of healthy and diseased groups, measured before and after calving. …”
Get full text

Gametocyte carriage in uncomplicated plasmodium falciparum malaria following treatment with artemisinin combination therapy: a systematic review and meta-analysis of individual patient data by Abdulla, S, Achan, J, Yeka, A, D'Alessandro, U, Adam, I, Alemayehu, B, Allan, R, Temu, E, Allen, E, Barnes, K, Anvikar, A, Valecha, N, Arinaitwe, E, Ashley, E, Carrara, V, McGready, R, Nosten, F, Lee, S, White, N, Asih, P, Awab, G, Dondorp, A, Fanello, C, Woodrow, C, Dahal, P, Guerin, P, Humphreys, G, Moreira, C, Nsanzabana, C, Price, R, Sibley, C, Stepniewska, K, Bassat, Q, Gonzalez, R, Baudin, E, Checchi, F, Espie, E, Grandesso, F, Nabasumba, C, Schramm, B, Björkman, A, Bompart, F, Lameyre, V, Bonnet, M, Borrmann, S, Bousema, T, Cenci, F, Cot, M, Faucher, J, Kapulu, M, Marsh, K, Mayxay, M, Newton, P, Roper, C, Deloron, P, Djimde, A, Fofana, B, Doumbo, O, Sagara, I, Dorsey, G, Rosenthal, P, Drakeley, C

“…An individual patient clinical data meta-analysis was undertaken to identify the determinants of gametocyte carriage and the comparative effects of four ACTs: artemether-lumefantrine (AL), artesunate/amodiaquine (AS-AQ), artesunate/mefloquine (AS-MQ), and dihydroartemisinin-piperaquine (DP).…”

Do dual-mobility cups reduce revision risk in femoral neck fractures compared with conventional tha designs? An international meta-analysis of arthroplasty registries by Farey, JE, Masters, J, Cuthbert, AR, Iversen, P, van Steenbergen, LN, Prentice, HA, Adie, S, Sayers, A, Whitehouse, MR, Paxton, EW, Costa, ML, Overgaard, S, Rogmark, C, Rolfson, O, Harris, IA

“…To determine a global hazard ratio of all-cause revision for dual-mobility compared with conventional THA designs, we used a pseudoindividual patient data approach to pool Kaplan-Meier prosthesis revision data from each registry and perform a meta-analysis. The pseudoindividual patient data approach is a validated technique for meta-analysis of aggregate time-to-event survival data, such as revision surgery, from multiple sources. …”

Comparison of diagnostic performance and inter-reader agreement between PI-RADS v2.1 and PI-RADS v2: systematic review and meta-analysis by Lee, Chau Hung, Vellayappan, Balamurugan, Tan, Cher Heng

“…To perform a systematic review and meta-analysis comparing diagnostic performance and inter reader agreement between PI-RADS v. 2.1 and PI-RADS v. 2 in the detection of clinically significant prostate cancer (csPCa).…”
Get full text

Comparative effectiveness of manual therapy, pharmacological treatment, exercise therapy, and education for neck pain (COMPETE study): protocol of a systematic review with network meta-analysis by de Oliveira-Souza, AIS, Barbosa-Silva, J, Gross, DP, da Costa, BR, Ballenberger, N, Pereira, TV, Dennett, L, Armijo-Olivo, S

“…The overall purpose of the study: (1) To identify which type of conservative treatment (education, ET, MT, and/or medication) and their combinations have the greatest probability of being most effective for neck pain using a network meta-analysis (NMA) approach. (2) To rank these conservative treatments in terms of safety (when possible) and effectiveness for managing neck pain. …”

Changes in cardiorespiratory fitness following exercise training prescribed relative to traditional intensity anchors and physiological thresholds: a systematic review with meta-analysis of individual participant data by Meyler, Samuel J. R., Swinton, Paul A., Bottoms, Lindsay, Dalleck, Lance C., Hunter, Ben, Sarzynski, Mark A., Wellsted, David, Williams, Camilla J., Muniz-Pumares, Daniel

“…Objectives The present meta-analysis sought to compare: (a) mean change in O2max, (b) proportion of individuals increasing O2max beyond a minimum important difference (MID) and (c) response variability in O2max between TRAD and THR. …”
Get full text