Integrate Traditional Chinese Medicine (TCM) into cognitive behavioural therapy to treat postpartum depression in Chinese culture contexts. by Han, Shuyu.

“…As in Chinese cultures, it is believed that any kind of drug has certain degree of side effects. In the end, all different kinds of factors have lead to the fact that most women suffering from postpartum disorders or depression left unwell treated. …”
Get full text

Predicting rifampicin resistance in M. tuberculosis using machine learning informed by protein structural and chemical features by Lynch, C, Adlard, D, Fowler, P

“…We have trained a learning models with the aim of complementing genetics-based drug susceptibility testing.</p> <br> <p><strong>Methods:</strong> We built a Test+Train dataset comprising 219 susceptible mutations. …”

Sharing is caring? International Society for Pharmacoepidemiology review and recommendations for sharing programming code by Tazare, J, Wang, SV, Gini, R, Prieto Alhambra, D, Arlett, P, Morales Leaver, DR, Morton, C, Logie, J, Popovic, J, Donegan, K, Schneeweiss, S, Douglas, I, Schultze, A

“…<p><strong> Methods: </p></strong>We conducted a literature review identifying all studies published in Pharmacoepidemiology and Drug Safety (PDS) between 2017 and 2022. …”

Tumor-targeted nano-assemblies for energy-blocking cocktail therapy in cancer by Chen, Manling, Liu, Yidu, Li, Yang, Liu, Xue

Get full text

Structure and function of the smoothened extracellular domain in vertebrate hedgehog signaling by Rohatgi, Rajat, Nachtergaele, Sigrid, Whalen, Daniel M, Mydock, Laurel K, Zhao, Zhonghua, Malinauskas, Tomas, Krishnan, Kathiresan, Covey, Douglas F, Siebold, Christian, Ingham, Philip William

“…Indeed, targeting of the Smo CRD by oxysterol-inspired small molecules can block signaling by all known classes of Hh activators and by clinically relevant Smo mutants.…”
Get full text
Get full text

Structural analysis of protein tyrosine phosphatase 1B reveals potentially druggable allosteric binding sites by Kumar, Ammu Prasanna, Nguyen, Minh Nhan, Verma, Chandra, Lukman, Suryani

Get full text

A multiphysics model of photo-sensitive hydrogels in response to light-thermo-pH-salt coupled stimuli for biomedical applications by Chen, Xiao, Li, Hua, Lam, King-Yeung

Get full text

Gender-based multi-aspect sentiment detection using multilabel learning by Kumar, J. Ashok, Trueman, Tina Esther, Cambria, Erik

Get full text

Synthesis, biological evaluation, and stability studies of raloxifene mono- and bis-sulfamates as dual-targeting agents by Zaraei, S-O, Dohle, W, Anbar, HS, El-Gamal, R, Leblond, B, Foster, PA, Al-Tel, TH, Potter, BVL, El-Gamal, MI

“…All three possible sulfamate derivatives of the selective estrogen receptor modulator Raloxifene (bis-sulfamate 7 and two mono-sulfamates 8–9) were synthesized and evaluated as inhibitors of the clinical drug target steroid sulfatase (STS), both in cell-free and in cell-based assays, and also as estrogen receptor (ER) modulators. …”

Maritime clusters and their development interplay with ports by Zhang Wei

“…Two case examples, namely London and Hong Kong, are drawn from these clusters, showing a port’s contribution to maritime cluster development. …”
Get full text

Understanding mechanisms that maintain social anxiety disorder in autistic individuals through the Clark and Wells (1995) model and beyond: a systematic review by Lei, J, Mason, C, Russell, A, Hollocks, M, Leigh, E

“…Most studies used only self-report measures that may have inflated associations observed between social anxiety and mechanisms. All studies employed cross-sectional design, and no causality inferences could be drawn. …”

On the most energy-efficient input functions and the lowest input energy of passive linear circuits by Smunyahirun, Radit

“…Finally, generalization of the most energy-efficient functions and the lowest input energy for any order circuits is drawn. A dummy function is introduced which is essential for generalization. …”
Get full text
Get full text

Real‐time imaging of dynamic cell reprogramming with nanosensors by Wiraja, Christian, Yeo, David Chenloong, Tham, Khek-Chian, Chew, Sharon Wan Ting, Lim, Xinhong, Xu, Chenjie

Get full text

Membrane reconstitution of monoamine oxidase enzymes on supported lipid bilayers by Wang, Liulin, Kabir H. Biswas, Yoon, Bo Kyeong, Kawakami, Lisa M., Park, Soohyun, Groves, Jay T., Li, Lin, Huang, Wei, Cho, Nam-Joon

Get full text

Peptide asparaginyl ligases—renegade peptide bond makers by Tam, James P., Chan, Ning-Yu, Liew, Heng Tai, Tan, Shaun J., Chen, Yu

Get full text

Does everyone have the potential to achieve their ideal body weight? Lay theories about body weight and support for price discrimination policies by Li, Kevin Shaobo, Kokkoris, Michail D., Savani, Krishna

Get full text

Structure and subunit arrangement of Mycobacterial F1FO ATP synthase and novel features of the unique mycobacterial subunit δ by Kamariah, Neelagandan, Huber, Roland G., Nartey, Wilson, Bhushan, Shashi, Bond, Peter J., Grüber, Gerhard

“…The arrangement of δ relative to the N-termini of the catalytic α3β3-headpiece and its potential as a drug target are discussed.…”
Get full text

RE teachers’ ways of balancing children’s existential concerns and the curriculum: mirrored through established RE approaches by Osbeck, C, Lilja, A, Fancourt, N

“…However, revisiting these approaches in combination with concrete examples of teachers’ experiences has brought our understanding further, and has also drawn attention to the need for awareness concerning the varying character of this relationship, as a tension, one between whose poles the teaching constantly moves or as one that falls apart in two different poles that do not necessarily need to be seen in the light of each other.…”

Tailoring the phase transition temperature to achieve high-performance cubic GeTe-based thermoelectrics by Ady Suwardi, Cao, Jing, Hu, Lei, Wei, Fengxia, Wu, Jing, Zhao, Yunshan, Lim, Su Hui, Yang, Lan, Tan, Xian Yi, Chien, Sheau Wei, Yin, Yan, Zhou, Wu-Xing, Wong, Nancy Lai Mun, Wang, Xizu, Lim, Suo Hon, Ni, Xiping, Li, Dengfeng, Yan, Qingyu, Zheng, Yun, Zhang, Gang, Xu, Jianwei

Get full text

Polymeric composites for powder-based additive manufacturing : materials and applications by Yuan, Shangqin, Shen, Fei, Chua, Chee Kai, Zhou, Kun

Get full text