Accumulation, depuration and distribution of cadmium and zinc in the green-lipped mussel Perna viridis (Linnaeus) under laboratory conditions by Yap, C.K., Ismail, A., Tan, S.G., Omar, H.

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Cluster-selective 57Fe labeling of a Twitch-domaincontaining radical SAM enzyme by Namkoong, Gil, Suess, Daniel LM

“…This method for cluster-selective isotopic labeling could in principle be applied to any protein that binds multiple Fe–S clusters so long as the clusters undergo exchange with exogenous Fe ions at sufficiently different rates.…”
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Antigen–antibody complex density and antibody-induced HLA protein unfolding influence Fc-mediated antibody effector function by Murali, TM, Gu, Y, Minhat, RA, Yap, J, Wood, KJ, Wang, C, Gascoigne, NRJ, Anantharaman, V, MacAry, PA

“…Donor-specific antibodies (DSAs) targeting mismatched human leukocyte antigen (HLA) molecules are one of the principal threats to long-term graft survival in solid organ transplantation. …”

Structural and molecular characterization of ligands activating the orphan nuclear receptor Nurr1 (NR4A2) by Ng, Xin Yi

“…By employing Surface Plasmon Resonance (SPR) and Nuclear Magnetic Resonance (NMR), C3 was identified to bind to the co-regulator binding pocket and is a strong candidate to be chemically-linked to L1, in hopes of increasing its potency as well as its binding affinity and specificity to Nurr1. …”
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Opportunity for genome engineering to enhance phosphate homeostasis in crops by Abdullah, Siti Nor Akmar, Ariffin, Norazrin, Md Hatta, Muhammad Asyraf, Kemat, Nurashikin

Structural and mechanistic insights into the Rel protein of Mycobacterium tuberculosis by Singal, Bharti

“…The NMR spectroscopy titration experiments with branched chain amino acids revealed the specific binding of valine to the MtRel ACT and showed structural rearrangement upon valine binding. …”
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The opioid receptor influences circadian rhythms in human keratinocytes through the β-arrestin pathway by Bigliardi, Paul, Junnarkar, Seetanshu, Markale, Chinmay, Lo, Sydney, Bigliardi, Elena, Kalyuzhny, Alex, Ong, Sheena, Dunn, Ray, Wahli, Walter, Bigliardi-Qi, Mei

“…In this study, we propose a significant association between cutaneous opioid receptor (OPr) activity and circadian rhythmicity. To investigate this link, we conducted a 48 h circadian rhythm experiment, during which RNA samples were collected every 5 h. …”
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Myristoylation restricts orientation of the GRASP domain on membranes and promotes membrane tethering by Heinrich, Frank, Nanda, Hirsh, Goh, Haw Zan, Bachert, Collin, Lösche, Mathias, Linstedt, Adam D.

“…The mammalian Golgi reassembly stacking protein (GRASP) proteins are Golgi-localized homotypic membrane tethers that organize Golgi stacks into a long, contiguous ribbon-like structure. It is unknown how GRASPs undergo trans pairing given that cis interactions between the proteins in the plane of the membrane are intrinsically favored. …”
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Breaking the symmetry : gradient in NiFe layered double hydroxide nanoarrays for efficient oxygen evolution by Zhou, Daojin, Jia, Yin, Duan, Xinxuan, Tang, Jialun, Xu, Jie, Liu, Dong, Xiong, Xuya, Zhang, Junming, Luo, Jun, Zheng, Lirong, Liu, Bin, Kuang, Yun, Sun, Xiaoming, Duan, Xue

“…Breaking the symmetry in catalysts through interface engineering has emerged as a new dimension in enhancing the catalytic performances, while the long-range asymmetry (i.e. in nanometer scale) in catalysts can hardly be achieved by alloying or doping. …”
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Integrated in-memory sensor and computing of artificial vision system based on reversible bonding transition-induced nitrogen-doped carbon quantum dots (N-CQDs) by Yu, Tianqi, Li, Jie, Lei, Wei, Shafe, Suhaidi, Mohtar, Mohd Nazim, Jindapetch, Nattha, van Dommelen, Paphavee, Zhao, Zhiwei

Protein interaction studies of crosslinked endolevanase aggregates from Bacillus lehensis G1 by Makki, Hotaf Hassan, Jaafar, Nardiah Rizwana, A. Rahman, Roshanida, Rahmat, Zaidah, Ni Nyoman Tri Puspaningsih, Ni Nyoman Tri Puspaningsih, Md. Illias, Rosli

“…The efficiency of cross-linked enzyme aggregates (CLEAs) is mainly affected by the strength and binding site of the formed linkages between the enzyme and cross-linker. …”
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Histone lysine and DNA methylation: dynamic marks in the chromatin by Belle, R

“…A common post translational modification is Nε-lysine methylation which is linked to transcriptional silencing or activation depending on the location within the nucleosome. …”

Label-free microfluidic cell sorting and detection for rapid blood analysis by Lu, Nan, Tay, Hui Min, Petchakup, Chayakorn, He, Linwei, Gong, Lingyan, Maw, Kay Khine, Leong, Sheng Yuan, Lok, Wan Wei, Ong, Hong Boon, Guo, Ruya, Li, Holden King Ho, Hou, Han Wei

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High-resolution HDX-MS reveals distinct mechanisms of RNA recognition and activation by RIG-I and MDA5 by Liu, Chuan-Fa, Zheng, Jie, Yong, Hui Yee, Panutdaporn, Nantika, Tang, Kai, Luo, Dahai

“…Our work demonstrates that RIG-I binds and responds differently to short triphosphorylated RNA and long duplex RNA and that sequential addition of RNA and ATP triggers specific allosteric effects leading to RIG-I CARDs activation. …”
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ANRIL promoter DNA methylation : a perinatal marker for later adiposity by Lillycrop, Karen, Murray, Robert, Cheong, Clara, Teh, Ai Ling, Clarke-Harris, Rebecca, Barton, Sheila, Costello, Paula, Garratt, Emma, Cook, Eloise, Titcombe, Philip, Shunmuganathan, Bhuvaneshwari, Liew, Samantha J., Chua, Yong-Cai, Lin, Xinyi, Wu, Yonghui, Burdge, Graham C., Cooper, Cyrus, Inskip, Hazel M., Karnani, Neerja, Hopkins, James C., Childs, Caroline E., Chavez, Carolina Paras, Calder, Philip C., Yap, Fabian, Lee, Yung Seng, Chong, Yap Seng, Melton, Philip E., Beilin, Lawrie, Huang, Rae-Chi, Gluckman, Peter D., Harvey, Nick, Hanson, Mark A., Holbrook, Joanna D., Godfrey, Keith M.

“…We identified a novel association between the level of CpG methylation at birth within the promoter of the long non-coding RNA ANRIL (encoded at CDKN2A) and childhood adiposity at age 6-years. …”
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Selective lighting up of epiberberine alkaloid fluorescence by fluorophore-switching aptamer and stoichiometric targeting of human telomeric DNA G-quadruplex multimer by Zhang, Lihua, Liu, Hua, Shao, Yong, Lin, Clement, Jia, Huan, Chen, Gang, Yang, Danzhou, Wang, Ying

“…More importantly, EPI, as the brightest FSA emitter among the alkaloids, can also serve as an efficient conformation probe for HTG DNA and discriminate the DNA G-quadruplex from the RNA counterpart. Furthermore, EPI can bind stoichiometrically to each G-quadruplex unit of long HTG DNA multimer with the most significant fluorescence enhancement, which has not been achieved by the previously reported probes. …”
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‘On-demand’ soft tissue adhesives by Mogal, Vishal Tukaram

“…Thus, indicating the tuning of adhesion depending on time of UV irradiation and type of diazirines functionalized on polyester films. The covalent crosslinking of hydroxyethyl methacrylate polymer brushes grafted on quartz surface to wetted tissues were studied following long-range UV light activation. …”
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Membrane-induced tau amyloid fibrils by El Mammeri, Nadia, Gampp, Olivia, Duan, Pu, Hong, Mei

“…Importantly, SUV-bound tau developed long fibrils that exhibit the characteristic β-sheet chemical shifts of Tyr310 in heparin-fibrillized tau. …”
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Elucidating the mechanism of mRNA transport using novel imaging technologies by Stoychev, D

“…One of defining features of the cells of the nervous system is their strong polarity. They have long projections that extend to distances that could be thousands of times the length of the cell body. …”

Purification of miraculin from miracle fruit [Synsepalum dulcifium (Schumach. & Thonn.) Daniell] by He, Zuxing

“…Synsepalum dulcificum, is a kind of berries, when eaten causes sour foods subsequently consumed to taste sweet. …”
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