Deep graph contrastive learning model for drug-drug interaction prediction by Jiang, Zhenyu, Gong, Zhi, Dai, Xiaopeng, Zhang, Hongyan, Ding, Pingjian, Shen, Cong

“…The existing methods often do not fully explore the relationship between the structural information and the functional information of drug molecules, resulting in low prediction accuracy for drug interactions, poor generalization, and other issues. …”
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Capping layer enabled controlled fragmentation of two-dimensional materials by cold drawing by Chen, Ming, Li, Dong, Hou, Yuxin, Gu, Mengxi, Zeng, Qingsheng, Ning, De, Li, Weimin, Zheng, Xue, Shao, Yan, Wang, Zhixun, Xia, Juan, Yang, Chunlei, Wei, Lei, Gao, Huajian

“…Compared to the abundant phenomenological results from experiments, however, the underlying mechanisms of this technique are not fully explored. Here, supported by experimental investigation, finite element calculations, and theoretical modeling, we systematically study the effect of a capping layer on the controlled fragmentation of 2D materials deposited on polymer substrates during the cold drawing. …”
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Liposomal encapsulation of pro-NO donor drug by Koh, Cheryl Jie Yan

“…In-vitro release study conducted using Phosphate buffered saline solution found that the drug was not fully encapsulated in the core of the liposomes, resulting in complete release of nitric oxide within a day. …”
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Development of biomimetic 3D cancer platform for drug testing by Ker, Sia Fong

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Dynamic drug combination methods for suppressing bacterial antibiotics resistance adaptation by Bhone, Myint Kyaw

“…It is resistant to many drugs and the glycopeptide vancomycin is the only available antibiotic that is active against MRSA infections. …”
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Second life as a platform for virtual design and manufacturing by Wong, Raymond Tuck Wai.

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One day at a time. by Ho, Qi Yi.

“…Amongst the many misconceptions present is that those suffering from mental disorders will never fully recover from the illness, creating a highly problematic and prejudiced standpoint on the matter. …”
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AI is a viable alternative to high throughput screening: a 318-target study by Wallach, Izhar, Bernard, Denzil, Nguyen, Kong, Ho, Gregory, Morrison, Adrian, Stecula, Adrian, Rosnik, Andreana, O’Sullivan, Ann Marie, Davtyan, Aram, Samudio, Ben, Thomas, Bill, Worley, Brad, Butler, Brittany, Laggner, Christian, Thayer, Desiree, Moharreri, Ehsan, Friedland, Greg, Truong, Ha, van den Bedem, Henry, Ng, Ho Leung, Stafford, Kate, Sarangapani, Krishna, Giesler, Kyle, Ngo, Lien, Mysinger, Michael, Ahmed, Mostafa, Anthis, Nicholas J., Henriksen, Niel, Gniewek, Pawel, Eckert, Sam, de Oliveira, Saulo, Suterwala, Shabbir, PrasadPrasad, Srimukh Veccham Krishna, Shek, Stefani, Contreras, Stephanie, Hare, Stephanie, Palazzo, Teresa, O’Brien, Terrence E., Van Grack, Tessa, Williams, Tiffany, Chern, Ting-Rong, Kenyon, Victor, Lee, Andreia H., Cann, Andrew B., Bergman, Bastiaan, Anderson, Brandon M., Cox, Bryan D., Warrington, Jeffrey M., Sorenson, Jon M., Goldenberg, Joshua M., Young, Matthew A., DeHaan, Nicholas, Pemberton, Ryan P., Schroedl, Stefan, Abramyan, Tigran M., Gupta, Tushita, Mysore, Venkatesh, Presser, Adam G., Ferrando, Adolfo A., Andricopulo, Adriano D., Ghosh, Agnidipta, Ayachi, Aicha Gharbi, Mushtaq, Aisha, Shaqra, Ala M., Toh, Alan Kie Leong, Smrcka, Alan V., Ciccia, Alberto, de Oliveira, Aldo Sena, Sverzhinsky, Aleksandr, de Sousa, Alessandra Mara, Agoulnik, Alexander I., Kushnir, Alexander, Freiberg, Alexander N., Statsyuk, Alexander V., Gingras, Alexandre R., Degterev, Alexei, Tomilov, Alexey, Vrielink, Alice, Garaeva, Alisa A., Bryant-Friedrich, Amanda, Caflisch, Amedeo, Patel, Amit K., Rangarajan, Amith Vikram, Matheeussen, An, Battistoni, Andrea, Caporali, Andrea, Chini, Andrea, Ilari, Andrea, Mattevi, Andrea, Foote, Andrea Talbot, Trabocchi, Andrea, Stahl, Andreas, Herr, Andrew B., Berti, Andrew, Freywald, Andrew, Reidenbach, Andrew G., Lam, Andrew, Cuddihy, Andrew R., White, Andrew, Taglialatela, Angelo

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Graphene oxide nanoplatelets potentiate anticancer effect of cisplatin in human lung cancer cells by Nur Farhanah Rosli, Fojtů, Michaela, Fisher, Adrian C., Pumera, Martin

“…However, despite vast research on GO, anticancer properties and drug carrier capabilities of graphene oxide nanoplatelets have yet to be fully explored. …”
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Modern Techniques in Biosensors : Detection Methods and Commercial Aspects / by Dutta, Gorachand, editor 643095, Biswas, Arindam, editor 643096, Chakrabarti, Amlan, editor 643097

Paint-your-mind : image creation for non-artists by Fang, Ran

“…Drawing or painting traditionally requires artistic skills and expertise – be it digital art or art forms of other mediums. …”
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A P450BM3 toolkit For C-H activation synthesis by Ren, X

“…Successful applications include drug metabolism, drug fragment diversification, synthesis of flavour and fragrance compounds, steroid oxidation, late-stage functionalisation in total synthesis, and C–H amination. …”

Fragmenstein: predicting protein–ligand structures of compounds derived from known crystallographic fragment hits using a strict conserved-binding–based methodology by Ferla, MP, Sánchez-García, R, Skyner, RE, Gahbauer, S, Taylor, JC, von Delft, F, Marsden, BD, Deane, CM

“…Current strategies centred on either merging or linking initial hits from fragment-based drug design (FBDD) crystallographic screens generally do not fully leaverage 3D structural information. …”

Publication of share recommendations in Lianhe Zaobao : testing for market response by Foo, Bin Gee, Tan, Tuan Kiong, Tan, Yin Hoon

“…Abnormal returns are also detected prior to the publication day, suggesting evidence that the market does not adjust instantaneously and fully upon the publication of the recommendations on the paper. …”
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Interfacial phenomena and biological recognition of mammalian cells on biomimetic materials by Chan, Vincent.

“…Our work has been mainly focused on the elucidation of bio-interfacial phenomena that are involved in cell therapeutics device and drug delivery systems. However, it is currently impossible to fully engineer cellular processes from the first principle based on molecular interactions due to gap between biology and nanotechology. …”
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Formal contracts mitigate social dilemmas in multi-agent reinforcement learning by Haupt, Andreas, Christoffersen, Phillip, Damani, Mehul, Hadfield-Menell, Dylan

“…It is an open problem in MARL to replicate such cooperative behaviors in selfish agents. In this work, we draw upon the idea of formal contracting from economics to overcome diverging incentives between agents in MARL. …”
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Effects of woven fabric embedment on thin film composite membranes for osmotically driven membrane processes (ODMPs) by Teo, Shino Yu Qin

“…While the technology itself shows potential, further advancement in ODMP membrane development is necessary to fully harness its power production capabilities. …”
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Effects of hemodynamic shear stress on circulating tumor cells by How, Yunhan

“…They also exhibit elongated cell morphology, greater drug resistance and higher expression of MnSOD, as compared to normal 231-C3.…”
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Utilizing food waste and thermoplastic starch (TPS) in 3D printed PLA formulations for sustainable and customizable controlled delivery systems by Wang, Liwen

“…With the addition of TPS, the drug release profile can be adjusted from 8 – 120 hours using different TPS ratios and different printed wall thicknesses. …”
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Synergistic, multi-level understanding of psychedelics: three systematic reviews and meta-analyses of their pharmacology, neuroimaging and phenomenology by Shinozuka, K, Jerotic, K, Mediano, P, Zhao, AT, Preller, KH, Carhart-Harris, R, Kringelbach, ML

“…Pharmacologically, LSD induces significantly more inositol phosphate formation at the 5-HT2A receptor than DMT and psilocin, yet there are no significant between-drug differences in the selectivity of psychedelics for the 5-HT2A, 5-HT2C, or D2 receptors, relative to the 5-HT1A receptor. …”