Biomimetic nanocomposites to control osteogenic differentiation of human mesenchymal stem cells by Liao, Susan, Nguyen, Luong T. H., Ngiam, Michelle, Wang, Charlene, Cheng, Ziyuan, Chan, Casey K., Ramakrishna, Seeram

“…Here, the production of materials based on nano-hydroxyapatite composites in scaffolds with nanofibrous and nanoporous topographies, designed to mimic the native bone matrix for applications in bone tissue engineering, is reported. …”
Get full text
Get full text

Synergistic effect of ultrasound and reinforced electrical environment by bioinspired periosteum for enhanced osteogenesis via immunomodulation of macrophage polarization through P... by Jiang, Ting, Yu, Fei, Zhou, Yuqi, Li, Ruomei, Zheng, Mengting, Jiang, Yangyang, Li, Zhenxia, Pan, Jun, Ouyang, Ningjuan

“…The periosteum plays a vital role in repairing bone defects. Researchers have demonstrated the existence of electrical potential in the periosteum and native bone, indicating that electrical signals are essential for functional bone regeneration. …”
Get full text

Deep learning approach to cervical segmentation from routine CT images by Duan, Yiming

“…This method can accu rately extract the information of bone joint location of slices and incorporate it into image features in the form of channels, which can improve the accuracy of multiple bone joint segmentation and classification. …”
Get full text

Impact of alginate encapsulation on myeloid leukemia cells. by Kyaw Htay.

“…Leukemia is a type of blood cancer characterized by a neoplastic proliferative expansion of hematopoietic stem cells, which grow in the bone marrow. Current leukemia studies using 2D culture flasks and in vivo animal models have not explained clearly yet how the interactions of cellular components in the bone marrow and their niches promote the growth of leukemic stem cells and thwart the chemotherapy. …”
Get full text

Dense/porous bioceramic composites by Hu, Yifei

“…These new types of porous materials were prepared for bone replacement and reconstruction. The pores were designed for bone ingrowth, whereas the graded pores and the dense cores were introduced for load bearing capability. …”
Get full text

Inhibition of endoplasmic reticulum stress using 4-phenyl butyrate mitigates osteoporosis in a mouse model of hindlimb suspension by Al-Daghestani, Hiba Saad Subhi

“…Osteoporosis (OP) characterized by micro-architectural deterioration of bone tissue is a common skeletal disease in the elderly and may lead to fragility fractures. …”
Get full text

3D patient specific instrumentation for high tibial osteotomy by Wong, Gina Khay Fong

“…The most time-intensive part of this project is creating the bone models as there are many alternatives to build it, with many unknown variables, like how the detection algorithm for the Hounsfield Units (HU) works, which helps to build the bone model. …”
Get full text

A Novel Approach to Open Reduction and Internal Fixation of Distal Radius Fractures Utilizing a Multi-Degree-of-Freedom Traction and Stabilization Device by Oeding, Jacob F., Bockman, Sam, Chiu, Harriet, Hua, Cheyenne, Connor, James, Slocum, Alexander

“…Open reduction and internal fixation (ORIF) is a surgical procedure performed with the objectives of restoring normal alignment and providing stability to broken bone fragments after a fracture. This procedure is increasingly used to treat fractures of the distal end of the radius. …”
Get full text

Characterisation of collagen type I/ type II composite scaffolds for osteochondral tissue engineering by Tamaddon, M

“…The goal of this thesis was to develop and characterise the layers of an osteochondral scaffold following the composition and structure of cartilage, the cartilage-bone interface and underlying bone to treat osteoarthritis or defects in bone and cartilage. …”

Cellular reporter for inflammation. by Yuhanis Abdullah Sunny.

“…We had found that our reporter could clearly show GFP expression well when the transduced bone marrow cells were induced to undergo inflammation. …”
Get full text

Living with fibrodysplasia ossificans progressiva: radiological images of a patient with extensive heterotopic ossification by Mohammed Mostafa Kotb, Omar, Usama Farghaly, Kaliya-Perumal, Arun-Kumar

“…Fibrodysplasia ossificans progressiva (FOP) is an exceptionally rare genetic disorder characterized by the progressive formation of heterotopic bone in soft tissues. Here, we present the radiological findings of an 18-year-old female diagnosed with FOP who had severe spinal and right-upper-limb abnormalities. …”
Get full text
Get full text

Knee joint measurement using CT scans for knee joint implant selection by Jing, Mei

“…With the help of the cutting guide, the surgeon cuts several pieces of bone from the end of the femur in order to match the implant shape, that’s called shaping the distal femoral bone. …”
Get full text

Translational GTPase BipA is involved in the maturation of a large subunit of bacterial ribosome at suboptimal temperature by Goh, Kwok Jian, Ero, Rya, Yan, Xin-Fu, Park, Jung Eun, Kundukad, Binu, Zheng, Jun, Sze, Siu Kwan, Gao, Yong-Gui

“…Based on the growth curve, soft agar swimming assay, and sucrose gradient sedimentation analysis, mutation of the catalytic residue His78 rendered plasmid-borne bipA unable to complement its deletion phenotypes. …”
Get full text

Neutrophil‐mediated enhancement of angiogenesis and osteogenesis in a novel triple cell co‐culture model with endothelial cells and osteoblasts by Herath, Thanuja D. K., Larbi, Anis, Teoh, Swee Hin, Kirkpatrick, C. James, Goh, Bee Tin

“…Repair and regeneration of critical‐sized bone defects remain a major challenge in orthopaedic and craniomaxillofacial surgery. …”
Get full text

New method for automatic generation of patient specific finite element models of the distal femur by Lek, Cheah Wen.

“…For model validation, the cortical bone was model with four-node shell elements while eight-node hexahedral elements and six-node wedge elements were used to model the cancellous bone. …”
Get full text

A medical image-based computer-aided diagnosis system for musculoskeletal disease and disorder. by Chuah, Tong Kuan

“…As part of the advancement to classifying subjects with BML, the thesis investigated textural parameters as potential biomarker in separating between bone marrow with and without bone marrow lesion. …”
Get full text

The hollow fiber bioreactor as a stroma-supported, serum-free ex vivo expansion platform for human umbilical cord blood cells by Xue, Cao, Kwek, Kenneth Y. C., Chan, Jerry Kok Yen, Chen, Qingfeng, Lim, Mayasari

“…The bone marrow microenvironment plays an integral role in the regulation of hematopoiesis. …”
Get full text
Get full text
Get full text

From the Andes to the coast: human mobility and diet in the Atacama desert during the late intermediate period (ad 900-1450) by Santana Sagredo, F

“…Human remains were analysed for tooth enamel, bone collagen, bone apatite, and hair-keratin. A second aim of the thesis was to provide new analysis of archaeological plants and animals of the area. …”

GHZ-like states in the Qubit-Qudit Rabi model by Shen, Yuan, Marchegiani, Giampiero, Catelani, Gianluigi, Amico, Luigi, Liu, Ai Qun, Fan, Weijun, Kwek, Leong Chuan

“…The ground state of the strongly coupled system is found to be of Greenberger-Horne-Zeilinger (GHZ) type. Therefore, despite the qubit-qudit strong coupling, the nature of the specific tripartite entanglement of the GHZ state suppresses the bipartite entanglement. …”
Get full text

Entanglement witness via symmetric two-body correlations by Tan, Ernest Y.-Z., Kaszlikowski, Dagomir, Kwek, Leong Chuan

“…We show that while the witness is unable to detect Greenberger-Horne-Zeilinger (GHZ) states, it is instead able to detect superpositions of Dicke states with GHZ states.…”
Get full text
Get full text