Cohort differences in physical health and disability in the United States and Europe by Gimeno, L, Goisis, A, Dowd, JB, Ploubidis, GB

“…While more chronic disease in younger cohorts need not necessarily translate to worse quality of life or higher rates of functional limitation, there is some suggestion that worsening chronic disease morbidity may be spilling over into worsening disability.…”

External validation of the QCovid 2 and 3 risk prediction algorithms for risk of COVID-19 hospitalisation and mortality in adults: a national cohort study in Scotland by Kerr, S, Millington, T, Rudan, I, McCowan, C, Tibble, H, Jeffrey, K, Fagbamigbe, AF, Simpson, CR, Robertson, C, Hippisley-Cox, J, Sheikh, A

“…</p> <p><strong>Conclusions:</strong> We found good discrimination of the QCovid 2 and 3 algorithms in Scotland, although performance was worse in higher age groups. Both the number of hospitalisations and the number of deaths were overestimated.…”

Serotonin transporter function and emotional behaviour by Lima, J

“…Subsequently, this increased sensitivity could lead to facilitated emotional learning in a 'for-better-or-for-worse' manner depending on their experiences in a given environment.…”

Prediction analysis of COVID-19 in Selangor by using backpropagation algorithm with conjugate gradient method by Ajmal Khan, Noor Amirah, Marjugi, Siti Mahani

“…Predictive analysis is utilized to take some earlier action to produce more effective outcomes, which is minimizing the number of COVID-19 patients, to avoid the COVID-19 disease spreading drastically and becoming worse. However, total performance is determined by the optimization approach discovered throughout the training phase. …”
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Robust fuzzy model predictive control of discrete-time Takagi–Sugeno systems with nonlinear local models by Teng, Long, Wang, Youyi, Cai, Wenjian, Li, Hua

“…For model predictive control of T-S fuzzy systems, the online computational burden is even worse. Especially for complex systems with severe nonlinearities, parametric uncertainties, and disturbances, existing model predictive control of T-S fuzzy systems usually leads to a very conservative solution or even no solution in some occasions. …”
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Process optimization for selective laser sintering of polypropylene by Wu, Kunlin

“…The result of flexural tests shows that specimens printed in Z orientation had worse performance in flexural properties, compared to specimens built in X, Y orientation. …”
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Comparison between CaO- and MgO-activated ground granulated blast-furnace slag (GGBS) for stabilization/solidification of Zn-contaminated clay slurry by Zhang, Yunhui, Ong, Yi Jie, Yi, Yaolin

“…The results showed that the application of the MgO-GGBS (GGBS dosage of 10 % and MgO of 0 %-3 % (of dry clay by mass)) had positive effects on the mechanical strength and Zn immobilization of the contaminated clay slurry while the CaO-GGBS affected negatively and the situation became even worse at a higher CaO dosage (0 %-1.5 % of dry clay by mass). …”
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Spatiotemporal assessment of water security in China: an integrated supply-demand coupling model by Liu, Bin, Zhang, Feilian, Qin, Xiaosheng, Wu, Zhe, Wang, Xiaolan, He, Yuanyuan

“…However, the ecological protection capacity was still highly insufficient, staying at an unsafe level for a long time; the security level of water resources and water ecology was still not optimistic and that of hydrological cycle was getting worse under the influence of human activities. From spatial distribution, the water security situation in the south part of China was generally better than that in the north. …”
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Modeling of outdoor natural ventilation and energy performance for multiple buildings in an industrial park of Singapore by Tang, Soon Tuck

“…The issue is further made worse by the growing need for air conditioning, which increases warmth and releases carbon dioxide. …”
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Encoding and decoding of serially concatenated codes for data storage systems by Yin, Ke.

“…A low-rate code is shown to have better performance in the waterfall region; while a high-rate code shows much lower error floor but it is at the expense of a slightly worse-off waterfall performance. Finally, we consider the application of eIRA codes to magnetic recording channels and simulate the performance of a turbo equalizer consisting of a BCJR channel detector and the eIRA decoder with various detection/decoding schedules. …”
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Yard crane dispatching based on real time data driven simulation for container terminals by Guo, Xi, Huang, Shell Ying, Hsu, Wen Jing, Low, Malcolm Yoke Hean

“…Our simulation results show that dispatching yard crane based on real time data driven simulation is of great value in improving yard crane performance in 3 scenarios with different vehicle arriving patterns and our results are 10% worse off a loosely estimated overall optimal performance result.…”
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Postural stability in cyclists by Preece, Mia, Grainger, Karl, Starrs, Paul

“…Conclusion: MTB balance was worse than RC balance, but both cycling groups were found to have better balance scores than the control. …”
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Culinary civilization: the representation of food culture in Ford Madox Ford, Gertrude Stein and Virginia Woolf by O'Brien, N

“…My original archival research shows that in <em>A Room of One’s Own</em> Woolf’s representation of the financial and culinary difference between men’s and women's dining in colleges at the University of Cambridge is justified and the material inequality was in fact worse than previously understood. I argue that the disparity in institutional food intensifies Woolf’s later reimagining of the term ‘civilization’ in <em>Three Guineas</em>. …”

When a test is more than just a test: findings from patient interviews and survey in the trial of a technology to measure antidepressant medication response (the PReDicT Trial) by Brown, S, Ploeger, C, Guo, B, Petersen, JJ, Beckenstrom, AC, Browning, M, Dawson, GR, Deckert, J, Dias, R, Dourish, CT, Gorwood, P, Kingslake, J, Menke, A, Sola, VP, Reif, A, Ruhe, H, Simon, J, Stäblein, M, van Schaik, A, Veltman, DJ, Morriss, R, PReDicT Group

“…</p> <br> <p><strong>Outcomes:</strong> Survey results showed the intervention was well received, with a majority of participants indicating they would use it again, and it gave them helpful extra information; a small minority indicated the Test made them feel worse. Qualitative data showed the Test had unexpected properties, including: instigating a process of reflection, giving participants feedback on progress and new understanding about their illness, and making participants feel supported and more engaged in treatment.…”

Clinical sub-phenotypes of Staphylococcus aureus bacteraemia by Swets, MC, Bakk, Z, Westgeest, AC, Berry, K, Cooper, G, Sim, W, Lee, RS, Gan, TY, Donlon, W, Besu, A, Heppenstall, E, Tysall, L, Dewar, S, de Boer, M, Fowler, VG, Dockrell, DH, Thwaites, GE, Pujol, M, Pallarès, N, Tebé, C, Carratalà, J, Szubert, A, Groeneveld, GH, Russell, CD

“…Microbiologic outcomes were worse in sub-phenotype C. In a secondary analysis of the ARREST trial, adjunctive rifampicin was associated with increased 84-day mortality in sub-phenotype B and improved microbiologic outcomes in sub-phenotype C.…”

Differences between neonatal units with high and low rates of breast milk feeding for very preterm babies at discharge: a qualitative study of staff experiences by McLeish, J, Aloysius, A, Gale, C, Quigley, M, Kurinczuk, JJ, Alderdice, F

“…The feeding challenges faced by mothers of very preterm babies could be made worse where there was no joined-up working between neonatal and postnatal staff; inadequate facilities for mothers to stay with their babies; and when opportunities were missed to give information about the importance of early initiation of expressing and to support mothers’ confidence during the transition to direct breastfeeding. …”

Association of Indoleamine 2,3-dioxygenase (ido) activity with outcome after cardiac surgery in adult patients by Stieger, A, Huber, M, Yu, Z, Kessler, BM, Fischer, R, Andereggen, L, Kobel, B, Stueber, F, Luedi, MM, Filipovic, MG

“…Increased IDO activity has been observed in various diseases and is associated with worse clinical outcomes. However, comprehensive research regarding its role in cardiac surgery remains limited. …”

Performance and validation of a digital memory test across the Alzheimer’s disease continuum by Toniolo, S, Attaallah, B, Maio, MR, Tabi, YA, Slavkova, E, Klar, VS, Saleh, Y, Idris, MI, Turner, V, Preul, C, Srowig, A, Butler, C, Thompson, S, Manohar, SG, Finke, K, Husain, M

“…A linear support vector model combining digital metrics achieved high accuracy and performed at par with standard testing in discriminating between elderly healthy controls and subjective cognitive decline (area under the curve 0.82) and between subjective cognitive decline and mild cognitive impairment (area under the curve 0.92), while performing worse in classifying between mild cognitive impairment and Alzheimer’s disease patients (area under the curve 0.75). …”

Immune checkpoint blockade sensitivity and progression-free survival associates with baseline CD8+ T cell clone size and cytotoxicity by Watson, RA, Tong, O, Cooper, R, Taylor, CA, Sharma, PK, de Los Aires, AV, Mahé, EA, Ruffieux, H, Nassiri, I, Middleton, MR, Fairfax, BP

“…Last, we demonstrated that individuals whose CD8⁺&nbsp;T cell pretreatment showed low cytotoxicity and had fewer expanded clones typically had worse outcomes after ICB treatment. This work further advances understanding of the molecular determinants of ICB response, assisting in the search for peripheral prognostic biomarkers and highlighting the importance of the baseline CD8⁺&nbsp;immune landscape in determining ICB response in metastatic melanoma.…”

Pre-shift anxiety and its factors influencing among nursing students during clinical placement in Universiti Sains Malaysia Health Campus by Ting, Veronica Lim Mei

“…Pre-shift anxiety can cause the healthcare students or healthcare professionals to feel anxious and panic right before starting their work and eventually negatively affect their performance. In a worse-case scenario, this can in turn negatively affect the patient care and patient outcomes. …”
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