Biotin-streptavidin binding interactions of dielectric filled silicon bulk acoustic resonators for smart label-free biochemical sensor applications by Heidari, Amir, Yoon, Yong-Jin, Park, Woo-Tae, Su, Pei-Chen, Miao, Jianmin, Park, Mi Kyoung, Lin, Julius Tsai Ming

“…Sensor performance of a dielectric filled silicon bulk acoustic resonator type label-free biosensor is verified with biotin-streptavidin binding interactions as a model system. …”
Get full text
Get full text

Biocementation of sand filled geotextile tubes by Yong, Hoi Zett

“…Nonetheless, the strength and durability of geotextile tubes that filled with sand or clay slurry still need to be improved. …”
Get full text

Mapping the structural and dynamical features of multiple p53 DNA binding domains : insights into loop 1 intrinsic dynamics by Lukman, Suryani., Lane, David P., Verma, Chandra S.

“…The transcription factor p53 regulates cellular integrity in response to stress. p53 is mutated in more than half of cancerous cells, with a majority of the mutations localized to the DNA binding domain (DBD). …”
Get full text
Get full text

The novel quinoline derivative SKA-346 as a KCa3.1 channel selective activator by Wong, Brandon Han Siang, Shim, Heesung, Goay, Stephanie Shee Min, Ong, Seow Theng, Nur Ayuni Binte Muhammad Taib, Chai, Kelila Xin Ye, Lim, Kerry, Huang, Dachuan, Ong, Choon Kiat, Vaiyapuri, Thamil Selvan, Cheah, Yeong Cheng, Wang, Yulan, Wulff, Heike, Webster, Richard David, Shelat, Vishalkumar G., Verma, Navin Kumar

“…In silico analysis using RosettaLigand and GLIDE demonstrated a well-converged pose of SKA-346 in a binding pocket at the interface between the calmodulin N-lobe and the S45A helix in the S4-S5 linker of the KCa3.1 channel. …”
Get full text

Employment value proposition in the social sector, Singapore by Ho, Rachel Hunling, Liang, Yun Tzu, Gan, Gek Sing

“…The widespread challenge of limited financial and human resources as well as ill-informed public are tremendous hindrances of social sector’s ability to do more.…”
Get full text

Bond order resolved 3d 5/2 and valence band chemical shifts of Ag surfaces and nanoclusters by Sun, Changqing, Qin, Wei, Wang, Yan, Huang, Yongli, Zhou, Zhaofeng, Yang, Chao

“…Incorporating the tight-binding theory and the bond order–length–strength (BOLS) correlation into the X-ray photoelectron spectra of Ag(111) and (100) surfaces and the Auger electron spectra of Ag nanoparticles deposited on Al2O3 and CeO2 substrates has led to quantitative information of the 3d5/2 and the valence binding energies of an isolated Ag atom and their shifts upon bulk, defect, surface, and nanocrystal formation. …”
Get full text
Get full text

Structural features that affect β2 integrin expression and regulation of adhesion by Guan, Siyu

“…In contrast, integrins with the β2-G150D mutation have no binding activities. LFA-1 with the β2-G716A mutation is constitutively active to bind ICAM-1 and requires only one activating agents to bind to ICAM-3. …”
Get full text

Different modes of regulation govern miRNA expression levels in Drosophila melanogaster by Lim, Mandy Yu Theng

“…Loquacious (Loqs) is a dsRNA-binding protein that binds Dicer-1 to cleave pre-miRNAs into short duplexes. …”
Get full text
Get full text

Protective Capacity of the Human Anamnestic Antibody Response during Acute Dengue Virus Infection by Xu, Meihui, Züst, Roland, Toh, Ying Xiu, Pfaff, Jennifer M., Kahle, Kristen M., Davidson, Edgar, Doranz, Benjamin J., Velumani, Sumathy, Tukijan, Farhana, Wang, Cheng-I, Fink, Katja

“…Half of the world's population is exposed to the risk of dengue virus infection. …”
Get full text
Get full text

Elucidating the mechanism of mRNA transport using novel imaging technologies by Stoychev, D

“…The MS2-MCP system is used to insert into mRNAs of interest special structures to which RNA-binding proteins, fused to a fluorescent protein such as GFP, can then bind. …”

Effects of condensed tannin fractions from Leucaena leucocephala (LAM.) De wit hybrid on methane mitigation, rumen fermentation and diversity of methanogens, protozoa and bacteria... by Mookiah, Saminathan

“…The b values representing the CT quantities needed to bind half of the maximum precipitable bovine serum albumin increased with decreasing MWs from fraction F1 to fraction F5, with values of 0.216, 0.295, 0.359, 0.425, and 0.460, respectively. …”
Get full text

Methyl and dimethyl o-xylenyl-substituted fullerene acceptors for polymer solar cells by Kim, Hee Un, Park, Jong Baek, Grimsdale, Andrew Clive, Hwang, Do-Hoon

“…These values correlate with the binding affinities of the fluorophore and quencher. …”
Get full text
Get full text

Use of peptide asparginyl ligases (PALs) in generating alternative non-Ig protein-drug conjugates for cancer therapy by See, Julia Jing Yi

“…Due to challenges regarding limited time constraints and unforeseen power outage, future investigation to assess Affibody & DARPin binding affinity (Kd) and half-maximal inhibitory concentration (IC50) to unravel further insights into non-Ig proteins with enzymatic ligation for therapeutic applications.…”
Get full text

Effects of beer advertisings on youth's intention towards alcohol consumption. by Yu, Angela Yah Kie.

Get full text

Structure of the C-terminal domain of the multifunctional ICP27 protein from herpes simplex virus 1 by Nordlund, Par, Patel, Vidhi, Dahlroth, Sue-Li, Rajakannan, Venkatachalam, Ho, Hai Ting, Cornvik, Tobias

“…The structure reveals the C-terminal half of ICP27 to have a novel fold consisting of -helices and long loops, along with a unique CHCC-type of zinc-binding motif. …”
Get full text
Get full text

A study of human monoclonal antibodies to influenza and ebola viruses by Rijal, P

“…Despite these features, half of the antibodies neutralised an Ebola surrogate virus <em>in vitro</em>, and many were therapeutic in a murine infection model. …”

Using an ER-specific optogenetic mechanostimulator to understand the mechanosensitivity of the endoplasmic reticulum by Song, Yutong, Zhao, Zhihao, Xu, Linyu, Huang, Peiyuan, Gao, Jiayang, Li, Jingxuan, Wang, Xuejie, Zhou, Yiren, Wang, Jinhui, Zhao, Wenting, Wang, Likun, Zheng, Chaogu, Gao, Bo, Jiang, Liwen, Liu, Kai, Guo, Yusong, Yao, Xiaoqiang, Duan, Liting

“…Sustained mechanostimuli increase the levels of binding-immunoglobulin protein (BiP) expression and phosphorylated eIF2α, two markers for ER stress. …”
Get full text

π-fused diazocines with controllable photoswitching properties as molecular tweezers by Yuan, Wei, Wu, Mengjiao, Qian, Cheng, Guo, Jingjing, Wu, Yinglong, He, Ting, Wei, Haipeng, Chen, Xiaokai, Wang, Dongdong, Liu, Jiawei, Zhao, Yue, Wang, Shihuai, Yang, Jie, Zhang, Zhongzheng, Chen, Yulan, Zhao, Yanli

“…This work may pave the way for designing novel photoswitches with long half-lives and lightcontrolled properties.…”
Get full text

Crack healing in reactive MgO-slag system via bacteria induced carbonate precipitation by Zheng, Yanying

“…In the Concrete industry, the most widely used binding ingredient for concrete, portland cement (PC), is accountable for around 8% of global anthropogenic carbon dioxide (CO2) emissions. …”
Get full text

Design of Cleavable Monomers and Cross-Linkers for the Synthesis of Degradable Polymer Architectures by Cardoso da Costa, Leticia

“…Here, we report the design of cleavable monomers and cross-linkers for the synthesis of degradable materials with different polymer architectures. The first half of this thesis focuses on the design of new degradable bottlebrush and brush-arm star polymers (BASPs) via ring-opening metathesis polymerization (ROMP). …”
Get full text