Structure and function of the smoothened extracellular domain in vertebrate hedgehog signaling by Rohatgi, Rajat, Nachtergaele, Sigrid, Whalen, Daniel M, Mydock, Laurel K, Zhao, Zhonghua, Malinauskas, Tomas, Krishnan, Kathiresan, Covey, Douglas F, Siebold, Christian, Ingham, Philip William

Get full text
Get full text

Re-understanding the mechanisms of action of the anti-mycobacterial drug bedaquiline by Sarathy, Jickky Palmae, Gruber, Gerhard, Dick, Thomas

Get full text

Mechanically-sensitive fluorochromism by molecular domino transformation in a Schiff base crystal by Sasaki, Toshiyuki, Nakane, Takanori, Kawamoto, Akihiro, Zhao, Yakai, Fujimoto, Yushi, Nishizawa, Tomohiro, Kalita, Nabadeep, Tsuzuki, Seiji, Ito, Fuyuki, Ramamurty, Upadrasta, Thakuria, Ranjit, Kurisu, Genji

Get full text

High-resolution HDX-MS reveals distinct mechanisms of RNA recognition and activation by RIG-I and MDA5 by Liu, Chuan-Fa, Zheng, Jie, Yong, Hui Yee, Panutdaporn, Nantika, Tang, Kai, Luo, Dahai

Get full text
Get full text

Oct4 switches partnering from Sox2 to Sox17 to reinterpret the enhancer code and specify endoderm by Ng, Calista Keow Leng, Herath, Wishva, Lili, Sun, Hutchins, Andrew P, Robson, Paul, Kolatkar, Prasanna R, Stanton, Lawrence W, Aksoy, Irene, Jauch, Ralf, Chen, Jiaxuan, Dyla, Mateusz, Divakar, Ushashree, Bogu, Gireesh K, Teo, Roy

Get full text
Get full text

Conformational landscape of the epidermal growth factor receptor kinase reveals a mutant specific allosteric pocket by Kannan, Srinivasaraghavan, Venkatachalam, Gireedhar, Lim, Hong Hwa, Surana, Uttam, Verma, Chandra

Get full text
Get full text

Bifunctional diazirine reagent for covalent dyeing of Kevlar and inert polymer materials by Liu, Richard Y., Luo, Shao-Xiong Lennon, Hirst, Elizabeth S., Doona, Christopher J., Swager, Timothy M.

Get full text

Targeting the GPI transamidase subunit GPAA1 abrogates the CD24 immune checkpoint in ovarian cancer by Mishra, Alok K., Ye, Tianyi, Banday, Shahid, Thakare, Ritesh P., Su, Chinh Tran-To, Pham, Ngoc N. H., Ali, Amjad, Kulshreshtha, Ankur, Chowdhury, Shreya Roy, Simone, Tessa M., Hu, Kai, Zhu, Lihua Julie, Eisenhaber, Birgit, Deibler, Sara K., Simin, Karl, Thompson, Paul R., Kelliher, Michelle A., Eisenhaber, Frank, Malonia, Sunil K., Green, Michael R.

Get full text

Functional comparison of human Adenomatous Polyposis Coli (APC) and APC-like in targeting beta-catenin for degradation by Schneikert, Jean, Chandra, Shree Harsha Vijaya, Ruppert, Jan Gustav, Ray, Suparna, Wenzel, Eva Maria, Behrens, Jürgen

Get full text
Get full text

Outer-membrane permeabilization, LPS transport inhibition: activity, interactions, and structures of thanatin derived antimicrobial peptides by Swaleeha Jaan Abdullah, Yan, Bernice Tan Siu, Palanivelu, Nithya, Dhanabal, Vidhya Bharathi, Bifani, Juan Pablo, Bhattacharjya, Surajit

Get full text

Alleviation of off-target effects from vector-encoded shRNAs via codelivered RNA decoys by Mockenhaupt, Stefan, Grosse, Stefanie, Rupp, Daniel, Bartenschlager, Ralf, Grimm, Dirk

Get full text
Get full text

Identification of bacterial biofilm and the Staphylococcus aureus derived protease, staphopain, on the skin surface of patients with atopic dermatitis by Sonesson, Andreas, Przybyszewska, Kornelia, Eriksson, Sigrid, Mörgelin, Matthias, Kjellström, Sven, Davies, Julia, Potempa, Jan, Schmidtchen, Artur

Get full text
Get full text

Carnobacterium maltaromaticum boosts intestinal vitamin D production to suppress colorectal cancer in female mice by Li, Qing, Chan, Hung, Liu, Wei-Xin, Liu, Chang-An, Zhou, Yunfei, Huang, Dan, Wang, Xueliang, Li, Xiaoxing, Xie, Chuan, Liu, Wing Ying-Zhi, Wang, Xian-Song, Ng, Siu Kin, Gou, Hongyan, Zhao, Liu-Yang, Fong, Winnie, Jiang, Lanping, Lin, Yufeng, Zhao, Guijun, Bai, Feihu, Liu, Xiaodong, Chen, Huarong, Zhang, Lin, Wong, Sunny Hei, Chan, Matthew Tak Vai, Wu, William Ka Kei, Yu, Jun

Get full text

Three-component Friedel-Crafts-type difunctionalization of ynamides with (hetero)arenes and iodine(iii) electrophile by Kikuchi, Jun, Nagata, Toya, Ito, Shingo, Yoshikai, Naohiko

Get full text

NMR structure, dynamics and interactions of the integrin β2 cytoplasmic tail with filamin domain IgFLNa21 by Chatterjee, Deepak, Tan, Suet-Mien, Bhattacharjya, Surajit, Lu, Lewis Zhiping

Get full text
Get full text

High-density lipoprotein function is modulated by the SARS-CoV-2 spike protein in a lipid-type dependent manner by Correa, Yubexi, Del Giudice, Rita, Waldie, Sarah, Thépaut, Michel, Micciula, Samantha, Gerelli, Yuri, Moulin, Martine, Delaunay, Clara, Fieschi, Franck, Pichler, Harald, Haertlein, Michael, Forsyth, V. Trevor, Le Brun, Anton, Moir, Michael, Russell, Robert A., Darwish, Tamim, Brinck, Jonas, Wodaje, Tigist, Jansen, Martin, Martín, César, Roosen-Runge, Felix, Cárdenas, Marité

Get full text

The dual GGDEF/EAL domain enzyme PA0285 is a Pseudomonas species housekeeping phosphodiesterase regulating early attachment and biofilm architecture by Eilers, Kira, Yam, Joey Kuok Hoong, Liu, Xianghui, Goh, Yu Fen, To, Ka-Ning, Paracuellos, Patricia, Morton, Richard, Brizuela, Jaime, Yong, Adeline Mei Hui, Givskov, Michael, Freibert, Sven-Andreas, Bange, Gert, Rice, Scott A., Steinchen, Wieland, Filloux, Alain

Get full text

Phosphatidylinositol 4,5-Bisphosphate Is an HCV NS5A Ligand and Mediates Replication of the Viral Genome by Cho, Nam-Joon, Lee, Choongho, Pang, Phillip S., Pham, Edward A., Fram, Benjamin, Nguyen, Khanh, Xiong, Anming, Sklan, Ella H., Elazar, Menashe, Koytak, Elif S., Kersten, Caroline, Kanazawa, Kay K., Frank, Curtis W., Glenn, Jeffrey S.

Get full text
Get full text

Designer broad-spectrum polyimidazolium antibiotics by Zhong, Wenbin, Shi, Zhenyu, Mahadevegowda, Surendra H., Liu, Bo, Zhang, Kaixi, Koh, Chong Hui, Ruan, Lin, Chen, Yahua, Zeden, Merve S., Pee, Carmen J. E., Marimuthu, Kalisvar, De, Partha Pratim, Ng, Oon Tek, Zhu, Yabin, Chi, Robin Yonggui, Hammond, Paula T., Yang, Liang, Gan, Yunn-Hwen, Pethe, Kevin, Greenberg, E. Peter, Gründling, Angelika, Chan-Park, Mary B.

Get full text

Translational GTPase BipA is involved in the maturation of a large subunit of bacterial ribosome at suboptimal temperature by Goh, Kwok Jian, Ero, Rya, Yan, Xin-Fu, Park, Jung Eun, Kundukad, Binu, Zheng, Jun, Sze, Siu Kwan, Gao, Yong-Gui

Get full text