Predicting cognitive scores from wearable-based digital physiological features using machine learning: data from a clinical trial in mild cognitive impairment by Rykov, Yuri G., Patterson, Michael D., Gangwar, Bikram A., Jabar, Syaheed B., Leonardo, Jacklyn, Ng, Kok Pin, Kandiah, Nagaendran

“…Background: Continuous assessment and remote monitoring of cognitive function in individuals with mild cognitive impairment (MCI) enables tracking therapeutic effects and modifying treatment to achieve better clinical outcomes. …”
Get full text

Early, very high-titre convalescent plasma therapy in clinically vulnerable individuals with mild COVID-19 (COVIC-19): protocol for a randomised, open-label trial by Desmarets, M, Hoffmann, S, Vauchy, C, Rijnders, BJA, Toussirot, E, Durrbach, A, Körper, S, Schrezenmeier, E, van der Schoot, CE, Harvala, H, Brunotte, G, Appl, T, Seifried, E, Tiberghien, P, Bradshaw, D, Roberts, DJ, Estcourt, LJ, Schrezenmeier, H

Regulation of mRNA abundance by polypyrimidine tract-binding protein-controlled alternate 5′ splice site choice by Hamid, Fursham M., Makeyev, Eugene V.

“…Here we report that polypyrimidine tract-binding protein 1 (Ptbp1/PTB/hnRNP-I) controls alternate 5′ and 3′ splice site (5′ss and 3′ss) usage in a large set of mammalian transcripts. …”
Get full text
Get full text

Molecular insights into evolution, mutations and receptor-binding specificity of influenza A and B viruses from outpatients and hospitalized patients in Singapore by Ivan, Fransiskus Xaverius, Zhou, Xinrui, Lau, Suk Hiang, Rashid, Shamima, Teo, Jasmine S. M., Lee, Hong Kai, Koay, Evelyn S., Chan, Kwai Peng, Leo, Yee Sin, Chen, Mark I. Cheng, Kwoh, Chee Keong, Chow, Vincent T.

“…Background: This study compared the genomes of influenza viruses that caused mild infections among outpatients and severe infections among hospitalized patients in Singapore, and characterized their molecular evolution and receptor-binding specificity. …”
Get full text

Performance and validation of a digital memory test across the Alzheimer’s disease continuum by Toniolo, S, Attaallah, B, Maio, MR, Tabi, YA, Slavkova, E, Klar, VS, Saleh, Y, Idris, MI, Turner, V, Preul, C, Srowig, A, Butler, C, Thompson, S, Manohar, SG, Finke, K, Husain, M

“…Most digital metrics were able to discriminate between healthy controls and patients with mild cognitive impairment and between mild cognitive impairment and Alzheimer’s disease patients. …”

Conformational changes involved in signal transduction in avian cryptochromes by Gehrckens, AS

“…</p> <p>Finally, by mapping conformational changes found in molecular dynamics simulations onto changes observed in a previous HDX-MS data set on the <em>Drosophila</em> cryptochrome, a few gaps left by the incomplete coverage of the current experimental data were filled by acquiring information on the phosphate-binding loop and the protrusion motif, two regions which have also been found to undergo light-induced structural changes for the avian cryptochromes investigated. …”

Attracting the right people in an IT labor-scarce economy : a study of Singapore and Philippine recruitment advertisements and strategies. by Guevarra, Monalou S.

“…Amidst increasing global IT labor shortage problems, organizations in Southeast Asia and the rest of the world are finding it more difficult to fill job vacancies for information technology (IT) related functions that require a new skills-set necessary for global competitiveness and growth. …”
Get full text

Efficacy of inactivated pasteurella multocida against the bacterial infections in broiler chickens by Koh, Sien Ling

“…Severe pneumonia and severe congestion and necrosis of lung parenchyma were also recorded. In contrast, mild hepatitis with mild necrosis and degeneration of hepatocytes and mild pneumonia with mild congestion, degeneration and necrosis at the lung parenchyma were recorded in all the scarified chickens in all group. …”
Get full text

Seroprevalence of SARS-CoV-2 in children and adolescents by Ratcliffe, H

“…It also allowed exploration of potential risk factors for COVID-19 seropositivity and the utility of symptom-based indicators of infection.</p> <br> <p>The findings of ‘STORY’ confirm that SARS-CoV-2 infections in children are generally asymptomatic or mild and rarely progress to severe disease and hospitalisation. …”

Enzymatic preparation of diacylglycerols: lipase screening, immobilization, characterization and glycerolysis performance by Xie, Rui, Peng, Xianwu, Lee, Yee-Ying, Xie, Pengkai, Tan, Chin-Ping, Wang, Yong, Zhang, Zhen

“…Backgrounds: Glycerolysis, with its advantages of readily available raw materials, simple operation, and mild reaction conditions, is a primary method for producing diacylglycerol (DAG). …”

Methods for the Study of Galactofuranose in Mycobacteria by Taylor, Katherine I.

“…Finally, we characterized the kinetics of a mild electrophile, the squaric ester, and assessed its utility in selectively binding and modifying a key galactofuranosyl transferase involved in mycobacterial cell wall biosynthesis. …”
Get full text

Influence of presumed influence on thinness as a beauty ideal for girls. by Soh, Wai Siong.

“…This is a direct response to Park’s (2005) call for further research on the Influence of Presumed Influence (IOPI) paradigm or indirect “two-step flow of mass media communication” which incorporates a “social context” into media effect studies. …”
Get full text

Study of 3PL selection and development in Singapore by Liu, Zelai

“…We also aim to find out how has the 3PL selection criteria changed over the years as the concept of Supply Chain Management (SCM) develops in recent years. …”
Get full text

Patterns of link reciprocity in directed, signed networks by Gallo, A, Saracco, F, Lambiotte, R, Garlaschelli, D, Squartini, T

“…Although part of the ambiguities can be solved by adopting a coarser definition of balance, our results call for a different theory, accounting for the directionality of edges in a coherent manner. …”

Re-evaluating GPT-4’s bar exam performance by Martínez, Eric

“…This paper begins by investigating the methodological challenges in documenting and verifying the 90th-percentile claim, presenting four sets of findings that indicate that OpenAI’s estimates of GPT-4’s UBE percentile are overinflated. …”
Get full text

Scheduling nonlinear divisible loads in a single level tree network by Suresh, Sundaram, Run, Cui, Kim, H. J., Robertazzi, T. G.

“…The problem of finding optimal load fraction is a computationally intensive task. …”
Get full text
Get full text

Deep brain stimulation of the hypothalamic region: a systematic review by Mofatteh, M, Mohamed, A, Mashayekhi, MS, Skandalakis, GP, Neudorfer, C, Arfaie, S, MohanaSundaram, A, Sabahi, M, Anand, A, Aboulhosn, R, Liao, X, Horn, A, Ashkan, K

“…Future large-scale studies with long-term follow-up are required to validate the safety and efficacy data and extend these findings.…”

Role of play and playfulness in online user experience by Victoria Chattopadhyay

Get full text

The moderation effect of vendor support on cloud computing adoption and firm performance by Teh, Raymond, Subramaniam, Anusuiya

“…This study aims to fill a knowledge gap in prior technology adoption studies by determining the moderating impact of vendor support on cloud computing adoption and firm performance in Malaysian SMEs. …”
Get full text

Student teachers learning to use Assessment for Learning in schools by Tan Chia Chun, D

“…Consequently, the implications for the design of teacher education programmes are a key part of the discussion stimulated by the findings.</p>…”