The LBP gene and its association with resistance to Aeromonas hydrophila in Tilapia by Xia, Jun Hong, Fu, Gui Hong, Liu, Feng, Yue, Gen Hua

“…In immune-related genes, the lipopolysaccharide-binding protein (LBP) gene is an important mediator of the inflammatory reaction. …”
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Digital keywords for China: perceptions and portrayals in English-language novels by Matthews, Graham, Cheung, Cally Hiu Tung

“…To date, we have collected 12,186 passages that include the words china or chinese with full metadata (author, title, country of origin, year of publication) for the years 1900–2017. …”
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Structural and biochemical mechanisms of NLRP1 inhibition by DPP9 by Huang, Menghang, Zhang, Xiaoxiao, Toh, Gee Ann, Gong, Qin, Wang, Jia, Han, Zhifu, Wu, Bin, Zhong, Franklin, Chai, Jijie

“…Nucleotide-binding domain, leucine-rich repeat receptors (NLRs) mediate innate immunity by forming inflammasomes. …”
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Investigation of Synthetic Proteins Produced via Automated Fast-Flow Peptide Synthesis by Cowfer, Amanda Elizabeth

“…I will discuss the iterative steps my team took to vary both chemical and mechanical and control variables to improve per-coupling yield enough to enable access to full-length single-domain proteins. On this journey, we utilized test peptides to validate synthesis quality and later synthesized a suite of full-length single-domain biologically active proteins. …”
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High-resolution HDX-MS reveals distinct mechanisms of RNA recognition and activation by RIG-I and MDA5 by Liu, Chuan-Fa, Zheng, Jie, Yong, Hui Yee, Panutdaporn, Nantika, Tang, Kai, Luo, Dahai

“…RIG-I and MDA5 are the major intracellular immune receptors that recognize viral RNA species and undergo a series of conformational transitions leading to the activation of the interferon-mediated antiviral response. However, to date, full-length RLRs have resisted crystallographic efforts and a molecular description of their activation pathways remains hypothetical. …”
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Amplifying signals in the tumor microenvironment for drug development and diagnostics by Martin Alonso, Maria Carmen

“…At the same time, improving the sensitivity of ctDNA-based tests, that remains limited by the scarcity of ctDNA in blood, holds the key to unlock the full potential of liquid biopsy across many important clinical applications. …”
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Synthesis of Au@Pd core/shell nanomaterials for high-performance ethanol oxidation reactions by Xu, Weichang

“…During CV scans, the onset potential and peak current density of backward peak reveals the binding affinity of –OH group and the catalytic activity, respectively. …”
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PESI: paratope-epitope set interaction for SARS-CoV-2 neutralization prediction by Wan, Zhang, Lin, Zhuoyi, Rashid, Shamima, Ng, Shaun Yue Hao, Yin, Rui, Senthilnath, J., Kwoh, Chee Keong

“…Traditional methods rely on features based on first principles derived from the binding interface. However, they are burdened by arduous data preprocessing from a limited quantity of protein structures. …”
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Targeted hematopoietic stem cell depletion through SCF-blockade by Chan, Yan Y., Ho, Pui Y., Dib, Carla, Swartzrock, Leah, Rayburn, Maire, Willner, Hana, Ko, Ethan, Ho, Katie, Down, Julian D., Wilkinson, Adam C., Nakauchi, Hiro, Denis, Morgane, Cool, Taylor, Czechowicz, Agnieszka

“…Results We confirm that only ACK2 inhibits SCF binding fully and prevents HSC proliferation in vitro. …”
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Purification of miraculin from miracle fruit [Synsepalum dulcifium (Schumach. & Thonn.) Daniell] by He, Zuxing

“…The effect of optimizing crude extract was more important than optimizing the binding buffer. In elution stage, the effect of imidazole was more important than acetic acid. …”
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Three-component Friedel-Crafts-type difunctionalization of ynamides with (hetero)arenes and iodine(iii) electrophile by Kikuchi, Jun, Nagata, Toya, Ito, Shingo, Yoshikai, Naohiko

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Integration of an Aptamer-Based Signal-On Probe and a Paper-Based Origami Preconcentrator for Small Molecule Biomarkers Detection by Lee, Na E., Hong, Ji H., Lee, Seungmin, Yoo, Yong K., Kim, Kang H., Park, Jeong S., Kim, Cheonjung, Yoon, Junghyo, Yoon, Dae S., Lee, Jeong H.

“…However, detecting small molecules such as cortisol using LFAs is challenging due to limited binding sites and weak signal generation. Here, we report the development of cortisol-specific aptamer-based probes and a paper-based origami preconcentrator (POP) to amplify the probe signal. …”
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Beyond Color: Lattice Gauge Theory for Strongly-Coupled Physics by Oare, Patrick R.

“…It is the interaction that yields the strong nuclear force that binds protons and neutrons together. The underlying mathematical picture of QCD is known exactly: it is an 𝑆𝑈(3) gauge theory coupled to six flavors of fermions (the quarks). …”
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The dual GGDEF/EAL domain enzyme PA0285 is a Pseudomonas species housekeeping phosphodiesterase regulating early attachment and biofilm architecture by Eilers, Kira, Yam, Joey Kuok Hoong, Liu, Xianghui, Goh, Yu Fen, To, Ka-Ning, Paracuellos, Patricia, Morton, Richard, Brizuela, Jaime, Yong, Adeline Mei Hui, Givskov, Michael, Freibert, Sven-Andreas, Bange, Gert, Rice, Scott A., Steinchen, Wieland, Filloux, Alain

“…We demonstrate that the C-terminal portion of PA0285 encompassing the GGDEF and EAL domains binds GTP and c-di-GMP, respectively, but only exhibits PDE activity in vitro. …”
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