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21W.730-2 Expository Writing - Food for Thought: Writing and Reading about Food and Culture, Fall 2005
Published 2005“…Food is at once the stuff of life and a potent symbol; it binds us to the earth, to our families, and to our cultures. …”
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Learning Object -
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Structural study of plant cellulose synthase and atypical profilin3
Published 2020“…A low-resolution model of oligomeric full-length cellulose synthase was also obtained by Cryo-EM. …”
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Thesis-Doctor of Philosophy -
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Part I Targeting RNA duplexes with modified triplex-forming oligonucleotides Part II Allostery within a Watson-Crick RNA duplex and its application in studying RNA recognition by R...
Published 2014“…Binding of full-length RIG-I and a triplex-forming oligonucleotide (TFO) also induces 2AP fluorescence enhancement. …”
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Thesis -
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Surface plasmon resonance (SPR) enhanced biosensors
Published 2016“…The point-of care device based on grating Au film for the detection of endotoxin (lipopolysaccharide, LPS) was demonstrated, which displayed excellent portability and good sensitivity. …”
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Thesis -
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Identification of novel functional compounds from forest onion and its biological activities against breast cancer
Published 2024“…A natural resource with potential activity against breast cancer is forest onion, Eleutherine bulbosa (Mill.) Urb., but the identity of its active constituents and their mechanisms of action remain unexplored. …”
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Article -
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Identification of RNA-Tis11b complexes in activated B cells.
Published 2010“…RNA-binding proteins (RBPs) play important roles in regulating gene expression at post-transcriptional level. …”
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Final Year Project (FYP) -
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Spontaneous emission of a quantum emitter near a Chern insulator : interplay of time-reversal symmetry breaking and Van Hove singularity
Published 2021“…To this end, we obtain the full real-frequency behavior of the conductivity tensor by performing a tight-binding calculation based on the Qi-Wu-Zhang model and using a Kubo formula, and derive the full electromagnetic Green tensor of the system, which breaks Onsager reciprocity. …”
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Journal Article -
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The LBP gene and its association with resistance to Aeromonas hydrophila in Tilapia
Published 2014“…In immune-related genes, the lipopolysaccharide-binding protein (LBP) gene is an important mediator of the inflammatory reaction. …”
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Journal Article -
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Digital keywords for China: perceptions and portrayals in English-language novels
Published 2023“…To date, we have collected 12,186 passages that include the words china or chinese with full metadata (author, title, country of origin, year of publication) for the years 1900–2017. …”
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Journal Article -
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Structural and biochemical mechanisms of NLRP1 inhibition by DPP9
Published 2022“…Nucleotide-binding domain, leucine-rich repeat receptors (NLRs) mediate innate immunity by forming inflammasomes. …”
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Journal Article -
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Investigation of Synthetic Proteins Produced via Automated Fast-Flow Peptide Synthesis
Published 2024“…I will discuss the iterative steps my team took to vary both chemical and mechanical and control variables to improve per-coupling yield enough to enable access to full-length single-domain proteins. On this journey, we utilized test peptides to validate synthesis quality and later synthesized a suite of full-length single-domain biologically active proteins. …”
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Thesis -
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High-resolution HDX-MS reveals distinct mechanisms of RNA recognition and activation by RIG-I and MDA5
Published 2015“…RIG-I and MDA5 are the major intracellular immune receptors that recognize viral RNA species and undergo a series of conformational transitions leading to the activation of the interferon-mediated antiviral response. However, to date, full-length RLRs have resisted crystallographic efforts and a molecular description of their activation pathways remains hypothetical. …”
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Journal Article -
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Amplifying signals in the tumor microenvironment for drug development and diagnostics
Published 2024“…At the same time, improving the sensitivity of ctDNA-based tests, that remains limited by the scarcity of ctDNA in blood, holds the key to unlock the full potential of liquid biopsy across many important clinical applications. …”
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Thesis -
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Synthesis of Au@Pd core/shell nanomaterials for high-performance ethanol oxidation reactions
Published 2019“…During CV scans, the onset potential and peak current density of backward peak reveals the binding affinity of –OH group and the catalytic activity, respectively. …”
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Thesis -
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PESI: paratope-epitope set interaction for SARS-CoV-2 neutralization prediction
Published 2024“…Traditional methods rely on features based on first principles derived from the binding interface. However, they are burdened by arduous data preprocessing from a limited quantity of protein structures. …”
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Conference Paper -
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Targeted hematopoietic stem cell depletion through SCF-blockade
Published 2024“…Results We confirm that only ACK2 inhibits SCF binding fully and prevents HSC proliferation in vitro. …”
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Article -
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Purification of miraculin from miracle fruit [Synsepalum dulcifium (Schumach. & Thonn.) Daniell]
Published 2015“…The effect of optimizing crude extract was more important than optimizing the binding buffer. In elution stage, the effect of imidazole was more important than acetic acid. …”
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Thesis -
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Layer-by-Layer Nanoparticles for Cytokine Delivery
Published 2024“…We also find that the LbL film conformation is key to maintaining therapeutic efficacy as thicker films hinder IL-12 delivery. …”
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Thesis