Time-restricted feeding modulates the DNA methylation landscape, attenuates hallmark neuropathology and cognitive impairment in a mouse model of vascular dementia by Selvaraji, Sharmelee, Efthymios, Motakis, Foo, Roger Sik Yin, Fann, David Y., Lai, Mitchell Kim Peng, Chen, Christopher Li Hsian, Lim, Kah-Leong, Arumugam, Thiruma V.

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Advanced attack and defense techniques in machine learning systems by Zhao, Mengchen

“…For single-credential scenarios, we demonstrate that the optimal defense strategy can be found by solving a binary combinatorial optimization problem called PEDS. For multiple-credential scenarios, we formulate it as a bilevel optimization problem for finding the optimal defense strategy and then reduce it to a single level optimization problem called PEMS using complementary slackness conditions. …”
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Beyond Color: Lattice Gauge Theory for Strongly-Coupled Physics by Oare, Patrick R.

“…Despite the focus on QCD, lattice methods find significant utility in studying other strongly-coupled gauge theories related to and unrelated to QCD. …”
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Granulocyte-macrophage colony-stimulating factor neutralisation in patients with axial spondyloarthritis in the UK (NAMASTE): a randomised, double-blind, placebo-controlled, phase... by Worth, C, Al-Mossawi, MH, MacDonald, J, Fisher, BA, Chan, A, Sengupta, R, Packham, J, Gaffney, K, Gullick, N, Cook, JA, Corn, TH, Teh, J, Machado, PM, Taylor, PC, Bowness, P

“…The primary endpoint was the proportion of participants who had an ASAS ≥20% improvement (ASAS20) clinical response at week 12 in the full analysis set (all randomly assigned participants). …”

The role of p53 and ASPP2 in neurodegenerative disease by Turnquist, C

“…Δ133p53 functions as a dominant-negative regulator of full-length (FL)Lp53 and represses senescence, while p53β as a co-activator of FLLp53, promotes senescence. …”

Remote digital cognitive assessment reveals cognitive deficits related to hippocampal atrophy in autoimmune limbic encephalitis: a cross-sectional validation study by Shibata, K, Attaallah, B, Tai, X-Y, Trender, W, Hellyer, PJ, Hampshire, A, Irani, SR, Manohar, SG, Husain, M

“…</p> <br> <p><strong>Interpretation:</strong> These findings demonstrate that subtle cognitive deficits in patients with chronic ALE, who often show full recovery in measures of disability and dependence on daily activities, are detectable using a remote online platform, which also relates to hippocampal atrophy. …”

Understanding lived experiences of bereaved parents of children with chronic life-threatening Illness : towards a culture-specific and meaning-oriented narrative E-writing interven... by Dutta, Oindrila

“…Qualitative framework analysis of post-intervention feedback highlighted participants’ satisfaction with the opportunity to reflect on their caregiving experiences, acceptance of an internet-and-narrative-based platform for self-expression and structured counseling support, and compatibility of the NeW-I therapeutic-protocol with participants’ needs. Taken together, findings from this pilot investigation indicate that NeW-I could enhance holistic pediatric palliative services in Singapore and a full-scale community trial with a larger and more diverse sample is warranted. …”
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Cytomegalovirus infection is associated with an increase in aortic stiffness in older men which may be mediated in part by CD4 memory T-cells by Kirkham, Frances, Pera, Alejandra, Simanek, Amanda M., Bano, Aalia, Morrow, George, Reus, Bernhard, Caserta, Stefano, Smith, Helen Elizabeth, Davies, Kevin A., Rajkumar, Chakravarthi, Kern, Florian

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Understanding lay conceptions of workplace criers: a prototype analysis by Tan, Terri Su-May

“…To investigate this possibility, four studies utilising the prototype approach were conducted with full-time employees in Singapore. In Study 1 (n = 163), participants freely listed their conceptions of workplace criers, which were coded into 51 features of differing frequency. …”
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Application and control for virtual synchronous generators by Guo, Yian

“…In the quest to harness the full potential of VSG technology, this paper delves deep into the foundational principles that govern its operation. …”
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Qualitative and quantitative accuracy evaluation of 18f-fdg PET/CT with TOF and NON-TOF system on beta value in BPL reconstruction by Hui, Ng Suk

“…Ordered Subset Expectation Maximisation (OSEM) is unable to achieve full convergence as image noise grows with each iteration, potentially compromising quantitative accuracy. …”
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An exploratory study for a new method to search for heavy neutrinos with data at the Large Hadron Collider (LHC) by Tan, Cherlene Shu Ning

“…We introduce a mechanism called the seesaw mechanism where we introduce right handed neutrinos to fill these gaps so that the picture is more complete. …”
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Structural and biochemical mechanisms of NLRP1 inhibition by DPP9 by Huang, Menghang, Zhang, Xiaoxiao, Toh, Gee Ann, Gong, Qin, Wang, Jia, Han, Zhifu, Wu, Bin, Zhong, Franklin, Chai, Jijie

“…Here we present structural and biochemical evidence that full-length rat NLRP1 (rNLRP1) and rat DPP9 (rDPP9) form a 2:1 complex that contains an autoinhibited rNLRP1 molecule and an active UPA-CARD fragment of rNLRP1. …”
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Space weather radiation effects on geostationary satellite solid-state power amplifiers by Lohmeyer, W. Q., Cahoy, K. L.

“…By contrast, a Monte Carlo simulation finds that on average, only 2.8 out of 21 (13%) of randomly assigned anomalies occur between 7 and 14days after an electron flux greater than 1.5 standard deviations above the mean. …”
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Targeted hematopoietic stem cell depletion through SCF-blockade by Chan, Yan Y., Ho, Pui Y., Dib, Carla, Swartzrock, Leah, Rayburn, Maire, Willner, Hana, Ko, Ethan, Ho, Katie, Down, Julian D., Wilkinson, Adam C., Nakauchi, Hiro, Denis, Morgane, Cool, Taylor, Czechowicz, Agnieszka

“…This combination was the only non-genotoxic conditioning approach that enabled robust donor engraftment post HSCT in WT mice. Conclusion These findings shed new insights into the mechanism of αCD117 mAb-mediated HSC depletion. …”
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Boon or bane? : The role of filial piety, relationship quality, caregiver gender on work-family interface among working caregivers of the elderly by Leong, Anthony Xueheng

“…Finally, gender was considered in a three-way interaction between PO and work-family interface in predicting caregiver wellbeing (vitality). Full-time workers who take care of an older relative were recruited; 195 participants (143 women, 52 men) were recruited. …”
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GeSn alloys fabricated by modified sputtering deposition by Qian, Li

“…The GexSn1-x thin films were fabricated on Si, Ge and GaAs substrates. …”
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Constrained neuro fuzzy inference methodology for explainable personalised modelling with applications on gene expression data by Singh, Balkaran, Doborjeh, Maryam, Doborjeh, Zohreh, Budhraja, Sugam, Tan, Samuel, Sumich, Alexander, Goh, Wilson, Lee, Jimmy, Lai, Edmund, Kasabov, Nikola

“…Interpretable models can potentially support early diagnosis before full disease manifestation. This is particularly important yet, challenging for mental health. …”
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Layer-by-Layer Nanoparticles for Cytokine Delivery by Pires, Ivan S.

“…We also find that the LbL film conformation is key to maintaining therapeutic efficacy as thicker films hinder IL-12 delivery. …”
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发达地区失地老人养老支持体系内卷化及其突破 — 基于苏州市的个案研究 = The involution of the eldercare system for the landless elderly in China’s developed regions : a case study based on Suzhou municipality... by 叶继红 Ye Jihong, 占少华 Zhan Shaohua

“…This article, based on an analysis of a “rural to residential”community in Suzhou Municipality, Jiangsu Province, finds that land acquisition has generated a strong impact on the life and pension style of the landless elderly. …”
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