DOK3 promotes atopic dermatitis by enabling the phosphatase PP4C to inhibit the T cell signaling mediator CARD11 by Loh Jia Tong, Teo, Joey Kay Hui, Kannan, Srinivasaraghavan, Verma, Chandra Shekhar, Andiappan, Anand Kumar, Lim, Hong-Hwa, Lam, Kong-Peng

“…A subset of hypomorphic CARD11 variants found in patients with atopic dermatitis bound more strongly than wild-type CARD11 to DOK3. Our findings suggest that the strength of the interaction of DOK3 with CARD11 may predispose individuals to developing atopic dermatitis.…”
Get full text

A multi-view context-aware approach to Android malware detection and malicious code localization by Narayanan, Annamalai, Chandramohan, Mahinthan, Chen, Lihui, Liu, Yang

“…Subsequently, it employs Multiple Kernel Learning (MKL) to find a weighted combination of the views which yields the best detection accuracy. …”
Get full text

PPARβ/δ prevents endoplasmic reticulum stress-associated inflammation and insulin resistance in skeletal muscle cells through an AMPK-dependent mechanism by Salvadó, Laia, Barroso, Emma, Gómez-Foix, Anna Maria, Palomer, Xavier, Michalik, Liliane, Wahli, Walter, Vázquez-Carrera, Manuel

“…Methods Studies were conducted in mouse C2C12 myotubes, in the human myogenic cell line LHCN-M2 and in skeletal muscle from wild-type and PPARβ/δ-deficient mice and mice exposed to a high-fat diet. …”
Get full text
Get full text

Application of in vitro erythropoiesis from bone marrow derived progenitors to detect and study genotoxicity by Shuga, Joseph F. (Joseph Francis)

Get full text

Global response of Vibrio cholerae to predation by heterotrophic protists by Hu, Jie

“…Indeed, a pigmented mutant, disrupted in VC1345 (hmgA), survived 100-fold better intracellularly in amoebae than did the wild type. The biomass of V. cholerae biofilms increased when the cell-free supernatant from a T. pyriformis culture was added, indicating that there may be chemical cues involved. …”
Get full text

TEOSINTE BRANCHED1/CYCLOIDEA/PROLIFERATING CELL FACTOR4 Interacts with WRINKLED1 to mediate seed oil biosynthesis by Kong, Que, Singh, Sanjay K., Mantyla, Jenny J., Pattanaik, Sitakanta, Guo, Liang, Yuan, Ling, Benning, Christoph, Ma, Wei

“…Collectively, our findings suggest that TCP4 represses fatty acid biosynthetic gene expression through interaction with AtWRI1, leading to a reduction of AtWRI1-mediated seed oil accumulation.…”
Get full text

Luteolin escape mutants of dengue virus map to prM and NS2B and reveal viral plasticity during maturation by Vasudevan, Subhash G., Peng, Minhua, Swarbrick, Crystall Marie Dawn, Chan, Kitti Wing-Ki, Luo, Dahai, Zhang, Wei, Lai, Xiaoping, Li, Geng

“…Interestingly we found that the replication kinetics of prM T19R-NS2B I114M double-mutant (DM) was similar to wild-type virus (WT). On the other hand the prM T79R single mutant (SM1) was attenuated and the NS2B I114M single mutant (SM2) showed enhanced replication. …”
Get full text
Get full text

The contribution of traumatic brain injury to Alzheimer’s disease progression by Zainal Azman, JAB

“…The J20-TBI model, compared to a wild-type TBI (WT-TBI) group, confirmed the two-hit hypothesis after acute contusion. 6-month-old (prodromal stage) and 12-month-old (AD dementia stage) J20 mice were used to study the impact of varying plaque burdens on APR. …”

Prevalence of West Nile virus in domesticated mammals (cattle, goat, horse and pig) in selected areas of Peninsular Malaysia by Mohammed, Mohammed Nma

“…In nature, the virus is maintained in a cycle between wild birds that served as amplifiers and Culex mosquitos which are the vectors. …”
Get full text

Scaling up parametric human recovery by Cai, Zhongang

“…Collectively, these efforts mark a significant advancement in the field through scaling up toward an unprecedentedly robust, high-performance parametric human recovery in the wild. First, we developed a low-cost data collection facility for massive human data acquisition. …”
Get full text

Falling for Rachel / by Roberts, Nora, 1950- author 465662

Radar-guided robot by Wang, Jiajun

“…Besides, the radar technology is wildly used nowadays. As an efficient method to detect object, the radar system can use radio frequency signals to detect the surrounding targets even in low-visibility environment. …”
Get full text

One-shot yield-cost relations in general quantum resource theories by Takagi, Ryuji, Regula, Bartosz, Wilde, Mark M.

Get full text

To what extent is national service a constraint on the development of football in Singapore by Liang, Brendan Jialiang

“…For a country that once had a 12-year plan to qualify for the 2010 FIFA World Cup to find itself in such dismal state, this paper sought to identify one of the possible causes of such failure. …”
Get full text

Influence Of Different Ratios Of Gdc-Sdc On Ssc/Gdc–Sdc Dual Composite Cathode For Intermediate-Temperature Solid Oxide Fuel Cells by Roslan, Mohammad Fikrey, Abd Rahman, Hamimah, Azmi, Mohd Azham, MohdTukimon, Mohd Faizal, Jaidi, Zolhafizi, Abdul Ghani, Muhammad Zul Idzham

“…SSC/GDC–SDC dual composite cathode powders were developed through high-energy ball milling and mixing at a fixed weight ratio of 50% SSC and 50% GDC–SDC. …”
Get full text

An Integrated Approach for Techno-Economic and Environmental Analysis of Power Generation from Pineapple Waste (S/O: 14486) by Omar, Salmah, Mohd Shafie, Shafini, Hami, Norsiah, Othman, Zakirah, Numan, Hariths, Nurwandi, Luthfi, Bachtiar, Iyan

“…The qualitative method through the interview and reports or content analysis was used in this research. The study's findings found that pineapple waste had a high potential for energy production, with 9857.6 tonnes of pineapple waste generating 9,918,177.4 kWh of electricity. …”
Get full text

Precision holography and supersymmetric theories on curved spaces by Genolini, P

“…<p>The formulation of rigid supersymmetric field theories on curved space leads to a number of results on their strongly-interacting regime, crucial from both the mathematical and physical point of view, starting from Witten’s topological twist of four-dimensional Yang–Mills theory. At the same time, strongly-coupled field theories may also be studied holographically via the AdS/CFT correspondence. …”

Consensus on current management of endometriosis by Johnson, NP, Hummelshoj, L, World Endometriosis Society Montpellier Consortium

Development of advanced Fe-based oxygen carriers for chemical looping applications by Fan, Qianwenhao

“…The main results and findings are summarized as follows. 1. We successfully synthesized oxygen carriers with nominal compositions of MgO•MgFe2O4 (1M1F) and 5MgO•MgFe2O4 (3M1F) using a simple ball-milling assisted solid-state reaction. …”
Get full text

Antidiabetic activity of Curculigo latifolia extracts in vitro and in vivo studies by Ishak, Nur Akmal

“…Curculigo latifolia (C. latifolia) plant grows wildly in tropical Asia especially in Malaysia. C. latifolia fruit has 9000 times the sweetness of sucrose. …”
Get full text