Genotype-phenotype maps for gene networks: from evolution to computation by Camargo, FQ

“…For both modelling frameworks, the GRN GP maps exhibit all the structural properties found in the literature, as well as simplicity bias. We also find that the number of genotypes mapping to the wild-type phenotypes for various GRNs is unusually large, and argue that this is evidence that the structure of the GP map plays an important role in determining evolutionary outcomes.…”

Strategies to mitigate establishment under the Wolbachia incompatible insect technique by Soh, Stacy, Ho, Soon Hoe, Ong, Janet, Seah, Annabel, Dickens, Borame Sue, Tan, Ken Wei, Koo, Joel Ruihan, Cook, Alex R., Sim, Shuzhen, Tan, Cheong Huat, Ng, Lee Ching, Lim, Jue Tao

“…Our simulations indicate that these interventions do not override the intended wild type suppression of the IIT approach. These findings will inform policy makers of possible ways to mitigate the potential establishment of Wolbachia using the IIT population control strategy.…”
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Biochemical characterisation of NS2B-NS3 protease from flaviviruses by Nah, Jojo Qian Hui

“…Here, we compared the enzymatic activities of DENV NS2B47- G4SG4 NS3 Wild Type (WT) pro, DENV NS2B47- G4SG4 NS3WTSSpro with DENV NS2B47- G4SG4 NS3WTSS and Zika virus (ZIKV) NS2B-NS3 WT pro. …”
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Factor Analysis Between Internal and External R&D with Operational Performance Moderated by Intellectual Property Rights by Anuar, Herman Shah, Mohamed Udin, Zulkifli, Mohd Nawi, Mohd Nasrun

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Experimental Characterization of Iron-Sulfur Cluster Excited States and their Relevance to Electron Transfer Reactions by Skeel, Brighton A.

“…We find additionally that the primary coordination sphere has a strong influence on the topography of these excited state landscapes, in particular that the donor properties of the ligands binding an [Fe₄S₄]¹⁺ cluster determine its ground state valence electron distribution. …”
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Inaudible components of the human infant cry influence haemodynamic responses in the breast region of mothers by Doi, Hirokazu, Sulpizio, Simone, Esposito, Gianluca, Katou, Masahiro, Nishina, Emi, Iriguchi, Mayuko, Honda, Manabu, Oohashi, Tsutomu, Bornstein, Marc H, Shinohara, Kazuyuki

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Coggle to boost collaborative learning: A prewriting strategy for writing Malaysia university english test by Mohammad Musab, Azmat Ali, Ahmad Mahfuz, Mohamed Anuar

“…Hence, textbook authors and curriculum developers can assist students by implementing Coggle mind mapping as a prewriting activity that supports creative writing.…”
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Integrating alternative and complementary medicine in the management of epilepsy and its comorbidities in low- and middle-income settings by Kariuki, SM, Newton, CRJC

“…Most of the convincing evidence is from biological-based therapies for example, multivitamin supplementation, ketogenic diet and cannabidiol extracts. Mind-based therapies e.g. Yoga and whole-body systems therapies e.g. …”

Localization using LEO satellites by Xia, Yingyu

“…Indeed, it is important to find an efficient method and this formulates the problem for the project. …”
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DOK3 promotes atopic dermatitis by enabling the phosphatase PP4C to inhibit the T cell signaling mediator CARD11 by Loh Jia Tong, Teo, Joey Kay Hui, Kannan, Srinivasaraghavan, Verma, Chandra Shekhar, Andiappan, Anand Kumar, Lim, Hong-Hwa, Lam, Kong-Peng

“…A subset of hypomorphic CARD11 variants found in patients with atopic dermatitis bound more strongly than wild-type CARD11 to DOK3. Our findings suggest that the strength of the interaction of DOK3 with CARD11 may predispose individuals to developing atopic dermatitis.…”
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A multi-view context-aware approach to Android malware detection and malicious code localization by Narayanan, Annamalai, Chandramohan, Mahinthan, Chen, Lihui, Liu, Yang

“…Subsequently, it employs Multiple Kernel Learning (MKL) to find a weighted combination of the views which yields the best detection accuracy. …”
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On the robustness of average losses for partial-label learning by Lv, Jiaqi, Liu, Biao, Feng, Lei, Xu, Ning, Xu, Miao, An, Bo, Niu, Gang, Geng, Xin, Sugiyama, Masashi

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Robust engineering in maintainability of building by Ismail, Neza

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A Sustainable Higher Education Ecosystem: A Development of Malaysian Transport Demand Management Framework (S/O 14195) by Abdul Hanan, Suhaila, Zainuddin, Nizamuddin, A. Jalil, Emy Ezura, Ahmad Mahyadin @ Mahidin, Fariza, Zakaria, Izatul Husna

“…Furthermore, while many Malaysian studies focused on the various aspects of sustainable transportation, researchers rarely studied all of these aspects with the TDM in mind. As a result, the current study attempts to fill these gaps. …”
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PPARβ/δ prevents endoplasmic reticulum stress-associated inflammation and insulin resistance in skeletal muscle cells through an AMPK-dependent mechanism by Salvadó, Laia, Barroso, Emma, Gómez-Foix, Anna Maria, Palomer, Xavier, Michalik, Liliane, Wahli, Walter, Vázquez-Carrera, Manuel

“…Methods Studies were conducted in mouse C2C12 myotubes, in the human myogenic cell line LHCN-M2 and in skeletal muscle from wild-type and PPARβ/δ-deficient mice and mice exposed to a high-fat diet. …”
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Global response of Vibrio cholerae to predation by heterotrophic protists by Hu, Jie

“…Indeed, a pigmented mutant, disrupted in VC1345 (hmgA), survived 100-fold better intracellularly in amoebae than did the wild type. The biomass of V. cholerae biofilms increased when the cell-free supernatant from a T. pyriformis culture was added, indicating that there may be chemical cues involved. …”
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Development, validation and the effects of culturally specific guided imagery and progressive muscle relaxation audio for patients with functional abdominal bloating by Shen, Vincent Tee Wei

“…The Rome Working Team had recommended the use of brain-gut behaviour therapies in treating Disorders of Gut-brain Interaction (DGBI). Mind-body techniques, including Guided Imagery (GI) and Progressive Muscle Relaxation (PMR) has been long used as therapeutic modalities for various disorders. …”
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Relevance judgment during health information seeking on a discussion forum by Pian, Wenjing

“…These data were analyzed to find associations between users’ eye movement patterns and the relevance criteria they used. …”
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TEOSINTE BRANCHED1/CYCLOIDEA/PROLIFERATING CELL FACTOR4 Interacts with WRINKLED1 to mediate seed oil biosynthesis by Kong, Que, Singh, Sanjay K., Mantyla, Jenny J., Pattanaik, Sitakanta, Guo, Liang, Yuan, Ling, Benning, Christoph, Ma, Wei

“…Collectively, our findings suggest that TCP4 represses fatty acid biosynthetic gene expression through interaction with AtWRI1, leading to a reduction of AtWRI1-mediated seed oil accumulation.…”
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Luteolin escape mutants of dengue virus map to prM and NS2B and reveal viral plasticity during maturation by Vasudevan, Subhash G., Peng, Minhua, Swarbrick, Crystall Marie Dawn, Chan, Kitti Wing-Ki, Luo, Dahai, Zhang, Wei, Lai, Xiaoping, Li, Geng

“…Interestingly we found that the replication kinetics of prM T19R-NS2B I114M double-mutant (DM) was similar to wild-type virus (WT). On the other hand the prM T79R single mutant (SM1) was attenuated and the NS2B I114M single mutant (SM2) showed enhanced replication. …”
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