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21
A facile alternative strategy of upcycling mixed plastic waste into vitrimers
Published 2023“…In this work, we have demonstrated upcycling of mixed plastic waste comprising a mixture of polyester, polyamide, and polyurethane through a reprocessable vitrimer of the depolymerized oligomers. Using poly(ethylene terephthalate) (PET) as a model polymer, we first demonstrated partial controlled depolymerization, using glycerol as a cleaving agent, to obtain branched PET oligomers. …”
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Journal Article -
22
Binding of TCR multimers and a TCR-like antibody with distinct fine-specificities is dependent on the surface density of HLA complexes
Published 2013“…Collectively, the results highlight the promiscuity of our soluble TCR, which could be an advantageous feature when targeting cells infected with a mutation-prone virus, but that binding of the soluble oligomeric TCR relies considerably on the surface density of the presented antigen.…”
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Journal Article -
23
Structural and mechanistic insights into the Rel protein of Mycobacterium tuberculosis
Published 2020“…The MtRel ACT structure was determined as a dimer and the oligomeric state was further confirmed using SAXS. The crucial dimeric interface residues were identified, and the mutants were studied to understand the role of these residues in dimerization. …”
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Thesis-Doctor of Philosophy -
24
NMR structure and activity relationship of defensin-analogous peptides
Published 2014“…For peptoids targeting Gram-positive bacteria, large oligomers formed by strong hydrophobic interactions between xanthone groups were observed in aqueous solution, lipid micelles and liposomes. …”
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Thesis -
25
Synthesis of heavy cyanide analogs for the design of novel Prussian blue analogs
Published 2023“…The factors that favor oligomerization are elucidated, providing a framework for understanding the stabilization of metal cyaphide complexes.…”
Thesis -
26
Viroporin activity of the foot-and-mouth disease virus non-structural 2B protein
Published 2015“…Viroporins form transmembrane pores in host cells via oligomerization, thereby destroying cellular homeostasis and inducing cytopathy for virus replication and virion release. …”
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Journal Article -
27
Synthesis and properties of amino- and guanidino-peptoid peptide nucleic acids
Published 2010“…The AP-PNA oligomers were synthesized on Rink amide PEGA resin using standard solid-phase Fmoc peptide synthesis protocols. …”
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Thesis -
28
1,2-dihydrophosphete: A platform for the molecular engineering of electroluminescent phosphorus materials for light-emitting devices
Published 2014“…In this work, the development of new π-conjugated oligomers incorporating a dihydrophosphete skeleton is reported. …”
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Journal Article -
29
Dissipative Particle Dynamics Study of Ultraviolet Ink Agglomeration in 3D Inkjet Printing
Published 2016“…Commercial UV inks used in AM applications today are usually composed of oligomers, monomers, photo-initiators, pigments, and other additives such as stabilizers and surfactants. …”
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Conference Paper -
30
A Self-Polymerizing Mesh of Nano-Tethers for the Mechanical Constraint of Degraded Intervertebral Discs—A Review of 25 Years of Pre-Clinical and Early Clinical Research
Published 2024“…Genipin polymers are self-forming tensile-load-carrying oligomers, derived from the gardenia fruit, that covalently bond to amines on collagen. …”
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Article -
31
A network aggregation model for amyloid-β dynamics and treatment of Alzheimer’s diseases at the brain scale
Published 2025“…Neurodegenerative diseases are associated with the assembly of specific proteins into oligomers and fibrillar aggregates. At the brain scale, these protein assemblies can diffuse through the brain and seed other regions, creating an autocatalytic protein progression. …”
Journal article -
32
SARS-CoV-2 accessory protein 7b forms homotetramers in detergent
Published 2023“…Inclusion of pentamers or higher oligomers in the SARS-2 7b model were detrimental to fit quality. …”
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Journal Article -
33
Synthesis and characterization of a novel biodegradable polylactide.
Published 2009“…Three-arm and four-arm star-shaped poly(DL-Lactide) (PLA) oligomers were successfully synthesized using glycerol and pentaerythritol initiator with 4-dimethylaminopyridine (DMAP) organocatalysts by ring-opening polymerization (ROP) in bulk. …”
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Final Year Project (FYP) -
34
Combatting pathogenic bacteria with synthetic immunotherapeutics from chitosan: antibody recruiting at engineered bacterial surface with peptidoglycan analogs
Published 2024“…In this work, we drew inspiration from synthetic peptidoglycan oligomers and successfully constructed antibody-recruiting peptidoglycan analogs, 2a-d, with excellent safety profiles and high efficiencies in recruiting antibodies across different conditions. …”
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Journal Article -
35
Modelling cerebrovascular pathology and the spread of amyloid beta in Alzheimer’s disease
Published 2025“…Experiments have revealed that amyloid beta oligomers induce microvascular mural cells to contract, thereby constricting capillaries and increasing resistance to blood flow. …”
Journal article -
36
Biophysical properties and supramolecular structure of self-assembled liposome/ε-peptide/DNA nanoparticles : correlation with gene delivery
Published 2013“…Using solid-phase synthesis, lysine can be oligomerized by a reaction of the peptide carboxylate with the ε-amino group to produce nontoxic, biodegradable cationic peptides, ε-oligo(l-lysines). …”
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Journal Article -
37
Arabidopsis RCD1 coordinates chloroplast and mitochondrial functions through interaction with ANAC transcription factors
Published 2019“…ROS alter the abundance, thiol redox state and oligomerization of the RCD1 protein in vivo, providing feedback control on its function. …”
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Journal Article -
38
Electronic structure and optical properties of conjugated molecules : SAC-CI study
Published 2013“…Electronic structure and optical properties of some organic conjugated molecules, that is the oligomers for organic-light emitting diodes (OLED), chelating hetero-atomic conjugated ligands, and UVB blocking molecules, have been investigated by the SAC-CI method. …”
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Conference Paper -
39
Interaction-mediating sequences within class I viral fusion glycoproteins : their roles in viral infection and in applications
Published 2015“…Using chemical crosslinking and immunofluorescence staining, in Paper II we could show that the S protein MPER could oligomerize and further heteromerize with the N-terminal internal fusion peptide (IFP). …”
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Thesis -
40
Unravelling 2-oxoglutarate turnover and substrate oxidation dynamics in 5-methylcytosine-oxidising TET enzymes
Published 2024“…Here, we profile 5-methylcytosine (5mC)-oxidising Ten-Eleven Translocation (TET) enzymes using MS and 1H NMR spectroscopy methods and reveal a high degree of substrate oxidation-independent 2OG turnover under a range of conditions. 2OG decarboxylase activity is substantial (>20% 2OG turned over after 1 h) in the absence of substrate, while, under substrate-saturating conditions, half of total 2OG consumption is uncoupled from substrate oxidation. 2OG kinetics are affected by substrate and non-substrate DNA oligomers, and the sequence-agnostic effects are observed in amoeboflagellate Naegleria gruberi NgTet1 and human TET2. …”
Journal article