DNA-damage orchestrates self-renewal and differentiation via reciprocal p53 family and Hippo/Wnt/TGF-β pathway activation in embryonic stem cells by Ye, Y, Xie, W, Wang, X, Tan, S, Yang, L, Ma, Z, Zhu, Z, Chen, X, Liu, X, O’Neill, E, Chang, L, Zhang, W

“…DNA damage and repair mechanisms have been largely elucidated in mutated cancer cells or simple eukaryotes, making valid interpretations on early development difficult. …”

Impact of precursor dosing on the surface passivation of AZO/AlOx stacks formed using atomic layer deposition by Wang, Y, Hobson, TD, Swallow, JEN, McNab, S, O'Sullivan, J, Soeriyadi, A, Niu, X, Fraser, RC, Dasgupta, A, Maitra, S, Altermatt, P, Weatherup, RS, Wright, M, Bonilla, RS

“…In addition, AZO has also been shown to passivate the c-Si surface. The ability for one material to provide all three properties without requiring any indium is advantageous in single junction and tandem solar devices. …”

Methodology research in clinical studies for Neglected Tropical Diseases (NTDs) of the skin: Addressing design, conduct and relevance for context and target population by Erber, A

“…</p> <p>Patients reported a number of treatment outcomes as important; the majority had only been insufficiently or not included in trials so far. …”

Disruption of seasonal influenza circulation and evolution during the 2009 H1N1 and COVID-19 pandemics in Southeastern Asia by Chen, Z, Tsui, JL, Cai, J, Su, S, Viboud, C, du Plessis, L, Lemey, P, Kraemer, MUG, Yu, H

“…East, South, and Southeast Asia (together referred to as Southeastern Asia hereafter) have been recognized as critical areas fuelling the global circulation of seasonal influenza. …”

How ready is general practice to improve quality in chronic kidney disease? A diagnostic analysis by Crinson, I, Gallagher, H, Thomas, N, de Lusignan, S

“…CKD guidelines may have been introduced without sufficient educational support.…”

Local rainfall is more likely than distant thunderstorms to affect movement behaviour in Northern Kenyan elephants by Mulder, T, Mortimer, B, Ferwerda, J, Vollrath, F

“…Previous research indicates that African savanna elephants change their movements preceding or coincident with local rainfall and it has been suggested that they respond to thunder in remote storms–perhaps reading seismic cues. …”

Stereoselective cyclisation cascades mediated by carbon electrophiles to access novel polycyclic scaffolds by Aynetdinova, DA

“…The cation-initiated polyene cyclisation to form carbocyclic rings, as well as heterocyclisation to form novel lactones, has been explored. High levels of diastereoselectivity in setting up new stereocentres during the cyclisation were achieved. …”

Molecular features associated with response to enasidenib plus azacitidine in newly diagnosed IDH2-mutated acute myeloid leukemia by Risueño, A, See, WL, Prebet, T, DiNardo, C, Döhner, H, Stein, EM, Fathi, AT, Vyas, P, Quek, L, Gandhi, A, Hasan, M

“…Of note, combination therapy improved event-free survival in patients with RAS-pathway mutations, which have been associated with resistance to enasidenib monotherapy. …”

Iranian and Saudi mutual (mis)representations: a study of the relationship between discourses of othering, political confrontation and sectarian strife by Mohammad, T

“…</p> <p>The study findings identify a paradigm shift in analysis of the Saudi-Iranian relationship, moving away from conventional geopolitical and sectarian paradigms, which have been dominant. I conclude that religious and sectarian identities remained a propaganda tool, whereas, the nature of the agenda promoted by both sides was political in nature. …”

A simulation study showed that linear regression and Mann-Whitney test can be used to analyse the Days Alive and at Home by day 30 (DAH30) outcome in a randomized controlled trial by Cook, J

“…</p> <br> <p><strong>Study Design and Setting:</strong> The days alive and at home by day 30 (DAH30) has been proposed a patient-centric outcome, and clinically relevant outcome suitable for clinical trials. …”

Essays on time series econometrics and financial econometrics by Xu, W

“…</p> <p>Time-varying volatility is common in macroeconomic data and has been incorporated into macroeconomic models in recent work. …”

HGVS Nomenclature 2024: improvements to community engagement, usability, and computability by Hart, RK, Fokkema, IFAC, DiStefano, M, Hastings, R, Laros, JFJ, Taylor, R, Wagner, AH, den Dunnen, JT

“…Methods: The HGVS Variant Nomenclature Committee (HVNC) now operates under the Human Genome Organization (HUGO), facilitating broader community feedback and collaboration with related standards organizations. The website has been redesigned using modern documentation tools and practices. …”

Quantitative proteomics reveals CLR interactome in primary human cells by Manolis, D, Hasan, S, Maraveyas, A, O'Brien, DP, Kessler, BM, Kramer, H, Nikitenko, LL

“…All identified interactors have not been previously reported as members of CLR interactome. …”

The amygdala and the pursuit of future rewards by Johnson, ST, Grabenhorst, F

“…Success and failure in these processes have been linked to differential life outcomes and psychiatric conditions. …”

A comparison of lesion mapping analyses based on CT versus MR imaging in stroke by Moore, MJ, Jenkinson, M, Griffanti, L, Huygelier, H, Gillebert, CR, Demeyere, N

“…However, no quantitative analysis has been conducted to support or refute this claim. This study reports an objective comparison of lesion-mapping analyses based on CT- and MRI-derived lesion masks to clarify how input imaging type may ultimately impact analysis results. …”

Is nitrogen present in Li3N·P2S5 solid electrolytes produced by ball milling? by Hartley, G, Jin, L, Bergner, B, Spencer Jolly, D, Rees, G, Zekoll, S, Ning, Z, Pateman, A, Holc, C, Adamson, P, Bruce, P

“…The mechanical milling of lithium nitride (Li₃N) with phosphorus pentasulfide (P₂S₅) has previously been reported to produce amorphous lithium-ion conductors, but the composition of these materials and the reactions occurring during the milling processes were hitherto undetermined. …”

Mucosal signatures of pathogenic T cells in HLA-B*27+ anterior uveitis and axial spondyloarthritis by Paley, MA, Yang, X, Hassman, LM, Penkava, F, Garner, LI, Paley, GL, Linskey, N, Agnew, R, Arantes de Faria, PH, Feng, A, Li, SY, Simone, D, Roberson, EDO, Ruzycki, PA, Esaulova, E, Laurent, J, Feigl-Lenzen, L, Springer, LE, Liu, C, Gillespie, GM, Bowness, P, Garcia, KC, Yokoyama, WM

“…Gastrointestinal inflammation has been suggested as a trigger of axSpA. We recently identified a bacterial peptide (YeiH) that can be presented by HLA-B*27 to expanded public T cell receptors (TCRs) in the joint in axSpA and the eye in B27AAU. …”

The role of ADAM10 and mucin-like molecules in modulating cell-cell interactions by Drexhage, L

“…Several mucins are excluded from the immunological synapse, and some have been reported to undergo removal from the cell surface of activated or apoptotic cells. …”

The KDEL receptor by Bräuer, P

“…Comparison with other membrane proteins suggests how the KDELR likely evolved from an ancestral secondary active transporter, demonstrating that transporter-like architectures may have been adapted to transmit signals across cell membranes.…”

Macroevolutionary history of Neotropical vegetation during the Cenozoic: a palynological perspective from Colombia by De La Parra Bonilla, G

“…This surprising megadiversity has been studied since times of Darwin and Humboldt, with different mechanisms proposed, not only to explain how such great diversity was produced but also how it is maintained. …”