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12061
Spontaneous ventricular tachyarrhythmias in β2-adrenoceptor transgenic mice in relation to cardiac interstitial fibrosis
Published 2015“…Myocardial fibrosis is regarded as a pivotal proarrhythmic substrate, but there have been no comprehensive studies showing a correlation between the severity of fibrosis and ventricular tachyarrhythmias (VTAs). …”
Journal article -
12062
A protocol for mobilising novel finance models for collaborative health promotion and disease prevention initiatives: taking a smart capacitating investment approach in the Invest4...
Published 2025“…The term “smart capacitating investment” (SCI) has previously been used to understand how to best boost social infrastructure investment in education, health, transport and housing across the EU. …”
Journal article -
12063
Genomic diversity and antimicrobial susceptibility of invasive Neisseria meningitidis in South Africa, 2016–2021
Published 2024“…<p><strong>Background:</strong> Invasive meningococcal isolates in South Africa have in previous years (<2008) been characterized by serogroup B, C, W, and Y lineages over time, with penicillin intermediate resistance (pen<sup>i</sup>) at 6%. …”
Journal article -
12064
BRCA1 regulation of breast cancer cell motility
Published 2023“…Mutations in BRCA1 have been implicated in the increased risk of developing several cancers. …”
Thesis -
12065
Evolution of an extracellular pathogen recognition mechanism in Solanaceae
Published 2018“…Although many <em>R</em> genes have been identified, the molecular mechanism by which they function is only understood for a few.…”
Thesis -
12066
Unfinished business: legalisation and implementation in business and human rights
Published 2016“…At the transnational level, the thesis discusses the Kimberley Process Certification Scheme (KPCS), the Extractive Industries Transparency Initiative (EITI), and the Voluntary Principles on Security and Human Rights (VPs), which have been selected as representative of the range of hybrid schemes increasingly developed by government and industry representatives to ameliorate the impact of TNCs on human rights.…”
Thesis -
12067
Association of Indoleamine 2,3-dioxygenase (ido) activity with outcome after cardiac surgery in adult patients
Published 2024“…Increased IDO activity has been observed in various diseases and is associated with worse clinical outcomes. …”
Journal article -
12068
Mechanistic and inhibition studies on gamma-butyrobetaine hydroxylase
Published 2014“…</p> <p>In addition to the mechanistic and functional studies, the potential of BBOX as a biocatalytic tool was examined. BBOX has been shown to catalyse a hydroxylation of the symmetrical dialkyl piperidine carboxylic acids, leading to formation of up to three stereocentres in one reaction.…”
Thesis -
12069
A Dirichlet-multinomial mixed model for determining differential abundance of mutational signatures
Published 2025“…These imprints are called mutational signatures and they have been characterised for point mutations, structural variants and copy number changes. …”
Journal article -
12070
Elucidating the mechanism of mRNA transport using novel imaging technologies
Published 2023“…This is partly due to the technically challenging aspect of capturing live mRNA dynamics and partly because only a few examples have been studied in detail. I begin to fill this technological gap by assessing and applying state-of-the-art methods from the fields of microscopy and image processing. …”
Thesis -
12071
Characterization of ubiquitin-activated DNA-protein crosslink repair in vitro
Published 2024“…SPRTN, a DNA-dependent metalloprotease, has been identified as the major protease in repairing DPCs. …”
Thesis -
12072
Building fabric improvement and heat pump deployment: a set of policy conundrums
Published 2024“…<p>Minimum building energy efficiency standards and retrofit targets for fabric improvement have long been a cornerstone of effective policy for energy demand. …”
Conference item -
12073
Immunological screening of Lassa virus among health workers and contacts of patients of Lassa fever in Ondo State
Published 2021“…It could also be suggestive that a good personal protective procedure is been practiced by the health workers, hence the low exposure. …”
Journal article -
12074
Practitioner, patient and public views on the acceptability of mobile stroke units in England and Wales: A mixed methods study
Published 2025“…Despite growing use of MSUs internationally, to date there have been no studies in NHS England and NHS Wales exploring the acceptability of MSUs to clinicians, patient and public representatives and other key stakeholders, which are important when considering potential feasibility and implementation. …”
Journal article -
12075
Curing through questioning? A cross-cultural analysis of Pyrrhonism, Madhyamaka, and their potential as philosophical therapy
Published 2021“…</p> <p>Despite their striking similarities, very few attempts have been made to learn about Pyrrhonism and Madhyamaka by studying them in conjunction. …”
Thesis -
12076
Zinc absorption from maize-based meals enriched with edible house crickets: a randomized crossover stable-isotope study in Kenyan pre-school children
Published 2025“…Edible insects have been proposed as a novel and sustainable source of protein and other essential nutrients for human consumption but nutrient absorption efficiency is still uncertain. …”
Journal article -
12077
Three essays on frictions of trade
Published 2018“…Neighbours of both countries would have been impacted due to the spillover effects.</p>…”
Thesis -
12078
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12079
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12080