Detection of low frequency artemisinin resistance mutations, C469Y, P553L and A675V, and fixed antifolate resistance mutations in asymptomatic primary school children in Kenya by Osoti, V, Wamae, K, Ndwiga, L, Gichuki, PM, Okoyo, C, Kepha, S, Keitany, K, Kandie, R, Aricha, S, Kiplagat, R, Mwandawiro, C, Bejon, P, Snow, RW, Ochola-Oyier, LI

“…These signals in asymptomatic and mixed infections would have been missed without deep sequencing.…”

Agamben's understanding of time and its implications for Christology by Wright, O

“…Whilst the contemporary reception of Agamben tends to treat these earlier theological discussions as anomalies, it is clear from the relative silence which has greeted the more recent works that a consistent force of theological thinking has not yet been perceived. </p> <p>The facet of “time” that I will investigate is limited to Agamben’s focus, namely time as it is experienced by human life in the present. …”

MAIT cells play a role in liver tissue repair via growth factor secretion by Sayaf, K, Tasin, I, Akther, HD, Garner, LC, Ramamurthy, N, Hackstein, CP, Russo, FP, Klenerman, P

“…These cells express transcriptional signatures associated with tissue repair both in vitro and in vivo, even though the direct mediators of MAIT cell-directed tissue repair in human tissues have not been defined. The aim of our study is to identify such factors and their in vivo relevance, especially in liver injury and regeneration.…”

The role of CD1a in dengue infection by Yang, J

“…However, compared to conventional MHC-activated T cells, the role of CD1a-restricted, lipid-specific T cells in dengue infection has not been studied.</p> <p>The aim of this project was to investigate the role of CD1a in the immunity of dengue virus infection.…”

The cingulum: anatomy, connectivity and what goes beyond by Kollenburg, L, Arnts, H, Green, A, Strauss, I, Vinke, S, Kurt, E

“…For over half a century, the cingulum has been the subject of neuroanatomical and therapeutic investigations owing to its wide range of functions and involvement in various neurological and psychiatric diseases. …”

Factors influencing macrophage phagocytosis and killing of Gram negative bacteria by Kurzyp, K

“…</p> <p>Bacterial factors influencing gonococcal interactions with human macrophages have not been studied extensively. I investigated the impact of gonococcal LOS glycans on uptake of bacteria by macrophages. …”

Legitimate priority-setting: refining accountability for reasonableness and its application within NICE by Rand, L

“…<p>In this dissertation, I examine Daniels and Sabin’s theory for fair and legitimate procedures, accountability for reasonableness (AFR), and its relationship to the National Institute for Health and Care Excellence (NICE). AFR has been widely adopted as an exemplar model of procedural decision-making for healthcare limit-setting. …”

Most of the world's largest flowers (genus Rafflesia) are now on the brink of extinction by Malabrigo Jr, P, Tobias, AB, Witono, J, Mursidawati, S, Susatya, A, Siti-Munirah, MY, Wicaksono, A, Raihandhany, R, Edwards, S, Thorogood, CJ

“…<br><strong> Summary<br></strong> The genus Rafflesia, which includes the world's largest flowers, has aroused curiosity among scientists for centuries and features prominently in local culture across Southeast Asia. The plant has long been used in ethnobotanical medicine and, more recently, as a source of revenue from ecotourism. …”

Essays on the market for corporate bonds by Levonmaa, A

“…Realized measures of volatility have been shown to be important in modelling and forecasting equity, exchange rate, and Treasury bill return volatility. …”

Adaptation of the WHO AWaRe (Access, Watch, Reserve) antibiotic classification to support national antimicrobial stewardship priorities in the UK: findings from a modified Delphi a... by Bou-Antoun, S, Oettle, RC, Leanord, A, Seaton, RA, Cooper, BS, Muller-Pebody, B, Conlon-Bingham, G, Kerr, F, Hand, KS, Sandoe, JAT, Llewelyn, MJ, Fleming, N, Brown, NM, Reid, N, Howard, P, Mckinstry, S, Malcolm, W, Demirjian, A, Ashiru-Oredope, D

“…Conclusions: An adapted UK-AWaRe list has been suggested through a consensus-reaching process. …”

Long COVID and cardiovascular disease: a prospective cohort study by Lawson, CA, Moss, AJ, Arnold, JR, Bagot, C, Banerjee, A, Berry, C, Greenwood, J, Hughes, AD, Khunti, K, Mills, NL, Neubauer, S, Raman, B, Sattar, N, Leavy, OC, Richardson, M, Elneima, O, McAuley, HJ, Shikotra, A, Singapuri, A, Sereno, M, Saunders, R, Harris, V, Houchen-Wolloff, L, Greening, NJ, Harrison, E, Docherty, AB, Lone, NI, Quint, JK, Chalmers, J, Ho, L-P, Horsley, A, Marks, M, Poinasamy, K, Evans, R, Wain, LV, Brightling, C, McCann, GP

“…<p><strong>Background:</strong> Pre-existing cardiovascular disease (CVD) or cardiovascular risk factors have been associated with an increased risk of complications following hospitalisation with COVID-19, but their impact on the rate of recovery following discharge is not known.…”

Genotype-phenotype maps for gene networks: from evolution to computation by Camargo, FQ

“…However, most of these properties have only been studied for self-assembling systems, such as protein complexes or RNA folding. …”

Understanding the disease mechanisms of cerebellar ataxia through induced pluripotent stem cell models by Wong, M

“…Although numerous causative genes have been identified, the underlying pathogenic mechanisms remain incompletely understood, due to the limited availability of human brain tissue and the lack of reliable disease models. …”

Barriers and opportunities for WHO ‘best buys’ non-communicable disease policy adoption and implementation from a political economy perspective: a complexity systematic review by Loffreda, G, Arakelyan, S, Bou-Orm, I, Holmer, H, Allen, LN, Witter, S, Ager, A, Diaconu, K

“…These policies have traditionally been treated as technical solutions, neglecting the critical influence of political economy dynamics. …”

Dental resin monomer enables unique NbO2/carbon lithium-ion battery negative electrode with exceptional performance by Ji, Q, Gao, X, Zhang, Q, Jin, L, Wang, D, Xia, Y, Yin, S, Xia, S, Hohn, N, Zuo, X, Wang, X, Xie, S, Xu, Z, Ma, L, Chen, L, Chen, G, Zhu, J, Hu, B, Müller-Buschbaum, P, Bruce, PG, Cheng, L

“…However, studies on NbO2 based lithium-ion battery negative electrodes have been rarely reported. In the present work, NbO2 4 nanoparticles homogeneously embedded in carbon matrix are synthesized using a dental resin monomer (bisphenol A glycidyl dimethacrylate, Bis-GMA) as solvent and carbon source and niobium ethoxide (NbETO) as the precursor. …”

‘An unimaginable challenge’: a cross-cultural qualitative study of ethics and decision-making around tracheostomy ventilation in patients with amyotrophic lateral sclerosis by Ozeki-Hayashi, R, Wilkinson, D

“…Previous studies have shown that doctors' values may affect decisionmaking. There have been no previous international qualitative comparisons of medical decision-making process for TIV or why practice varies. …”

Identifying falsified COVID-19 vaccines by analysing vaccine vial label and excipient profiles using MALDI-ToF mass spectrometry by Arman, BY, Clarke, R, Bharucha, T, Fernandez, LG, Walsby-Tickle, J, Deats, M, Mosca, S, Lin, Q, Banerjee, S, Chunekar, SR, Patil, KD, Gairola, S, Dunachie, S, Merchant, HA, Stokes, R, Kuwana, R, Maes, A, Charrier, J, Probert, F, Caillet, C, Matousek, P, McCullagh, J, Newton, PN, Zitzmann, N, Gangadharan, B

“…However, these developments are associated with the risk of a surge of substandard and falsified (SF) vaccines, as illustrated by the 184 incidents with SF and diverted COVID-19 vaccines which have been reported during the pandemic in 48 countries, with a paucity of methods for their detection in supply chains. …”

Associations of maternal night shift work during pregnancy with DNA methylation in offspring: a meta-analysis in the PACE consortium by Marques, IF, Domènech-Panicello, C, Geurtsen, ML, Hoang, TT, Richmond, R, Polinski, K, Sirignano, L, Page, CM, Binter, A, Everson, T, Burt, A, Deuschle, M, Gilles, M, Streit, F, Mumford, SL, Magnus, P, Reiss, IKM, Vermeulen, MJ, Witt, SH, Chaves, I, Yeung, E, London, SJ, Guxens, M, Felix, JF

“…Background: Night shift work during pregnancy has been associated with differential DNA methylation in placental tissue, but no studies have explored this association in cord blood. …”

Molecular mechanisms relevant to the maintenance of locomotor control by Guo, F

“…Preferential degeneration of the <em>Penk</em>+ MSNs has been observed at early stage of Huntington disease (HD). …”

A separation-of-powers model for a trustworthy and open cloud computing ecosystem by Ruan, A

“…Trusted Cloud models have been proposed, which establish a Root-of-Trust inside the cloud and vouch for the trustworthiness of the cloud services. …”