Regulation and function of innate-like T cells by Hagel, JP

“…It is expressed by NK- and T-cell subsets, particularly by innate-like T cells such as MAIT and γδT cells. CD161-expressing T-cell subsets share a transcriptional and functional phenotype, including the ability to be activated by cytokines in a T-cell receptor-independent manner, similar to NK cells. …”

PRMT5 controls the innate immune response by Zhang, C

“…This study explores a novel pathway involving an innate immune response triggered by PRMT5 and E2F1-mediated RNA splicing. …”

Inosine-containing mRNA induces an innate immune response and is translated with lower efficiency by Bao, Caroline

“…While A-to-I editing activity is required for endogenous RNA to evade the innate immune response, our results show that inosine-containing IVT RNA induces an elevated immune response and is translated at a lower efficiency. …”
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Natural IgG antibodies provide innate protection against ficolin-opsonized bacteria by Panda, Saswati, Zhang, Jing, Tan, Nguan Soon, Ho, Bow, Ding, Jeak Ling

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The stress granule protein G3BP1 binds viral dsRNA and RIG-I to enhance interferon-β response by Kim, Susana Soo-Yeon, Sze, Lynette, Lam, Kong-Peng

Subjects: “…Innate Immunity…”
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Development of ISB 1442, a CD38 and CD47 bispecific biparatopic antibody innate cell modulator for the treatment of multiple myeloma by Grandclément, C, Estoppey, C, Dheilly, E, Panagopoulou, M, Monney, T, Dreyfus, C, Loyau, J, Labanca, V, Drake, A, De Angelis, S, Rubod, A, Frei, J, Caro, LN, Blein, S, Martini, E, Chimen, M, Matthes, T, Kaya, Z, Edwards, CM, Edwards, JR, Menoret, E, Kervoelen, C, Pellat-Deceunynck, C, Moreau, P, Mbow, ML, Srivastava, A, Dyson, MR, Zhukovsky, EA, Perro, M, Sammicheli, S

Immune correlates of early clearance of Mycobacterium tuberculosis among tuberculosis household contacts in Indonesia by Setiabudiawan, TP, Apriani, L, Verrall, AJ, Utami, F, Schneider, M, Indrati, AR, Halim, PP, Kaplonek, P, Malca, H, Lee, JS, Moorlag, SJCFM, de Bree, LCJ, Mourits, VP, Joosten, LAB, Netea, MG, Alisjahbana, B, McNamara, RP, Alter, G, van Laarhoven, A, Ussher, JE, Sharples, K, Koeken, VACM, Hill, PC, van Crevel, R

“…This could be explained by an IFN-γ-independent adaptive immune response, or an effective innate host response clearing Mycobacterium tuberculosis (Mtb) without adaptive immunity. …”

Using an aerosol human BCG infection model to define the early immune response in the lung and systemic circulation by Marshall, JL

“…Initial immune events driven by the innate system play an important role in the development of adaptive immunity and protection. …”

Interleukin-26 (IL-26) is a novel anti-microbial peptide produced by T cells in response to staphylococcal enterotoxin by Woetmann, Anders, Alhede, Morten, Dabelsteen, Sally, Bjarnsholt, Thomas, Rybtke, Morten, Nastasi, Claudia, Krejsgaard, Thorbjørn, Andersen, Mads Hald, Bonefeld, Charlotte M., Geisler, Carsten, Givskov, Michael, Odum, Niels

“…Anti-microbial peptides are produced at outer and inner surfaces by epithelia and innate immune cells in response to bacterial infection. …”
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Identification of novel interactions between MicroRNAs and pattern-recognition receptor signalling in dentritic cells by Pichulik, T

“…Notably, miR-650 displays reciprocal target regulation with miR-155, a well-studied miRNA with established functions in the innate immune system, thus suggesting cooperativity between the two miRNAs.…”

Naturalistic multimodal emotion data with deep learning can advance the theoretical understanding of emotion by Angkasirisan, T

“…Emotions are diversely conceptualised as innate responses (evolutionary view), mental constructs (constructivist view), cognitive evaluations (appraisal view), or self-organising states (dynamical systems view). …”

论致良知的公共伦理意涵 = Analysis of the value of Zhi Liang Zhi as public ethics by 吴建璋 Oh, Jian Zhang

“…Prior to this, from the previous Song Dynasty to the early stages of Ming Dynasty, the society was heavily influenced by the Chengzhu school of thought (程朱理学) which proposes that tianli （天理）is something that is out there in the world for people to know, to acquire and that one must strive to understand tianli and eliminate the renyu （人欲）which is innate in one’s consciousness. However, when Wang proposed Zhi Liang Zhi in the mid-Ming era, it was a revolutionary thought which suggests that tianli is innate in one’s consciousness just as renyu and that one can eventually extend this innate tianli to the rest of the world, or in a modern sense formulating public ethics. …”
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A feasibility study on computational prediction on the death domain superfamily protein oligomers by Zhang, Jiawen

“…Death Domain (DD) is one of the largest domain super-families, which comprises of the death domain(DD) subfamily, the death effector domain (DED) subfamily, the pyrin domain (PYD) subfamily, and the caspase recruitment domain (CARD) subfamily, that can lead to inflammatory response and cell death in innate immunity system. CARD-containing proteins are involved in processes relating to inflammation and apoptosis. …”
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Gender dimorphism in parasitic behavioural manipulation hypothesis by Abdulai-Saiku, Samira

“…Rather I propose manipulation affects the negotiation of the approach-avoidance conflict which is an important part of all aspects of social behaviour. Innate social behavioural responses are mainly mediated by mechanisms that are gender dimorphic in the substrates they employ. …”
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Magical portal : connecting with imaginary worlds by See, Yu Xuan

“…What happens to our innate creativity when we age? How can we, as creative as possible, help young adults tap into their more imaginative selves? …”
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Harnessing novel strategies and cell types to overcome immune tolerance during adoptive cell therapy in cancer by Neo, Shi Yong, Xu, Shengli, Chong, Joni, Lam, Kong-Peng, Wu, Jing

“…Finally, we discuss the potential of other innate or innate-like immune cell types currently being explored as promising CAR-cell alternatives that seek to address the limitations of conventional adoptive cell therapies.…”
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Development of immune-modulatory RNAS to regulate RIG-I-like receptors mediated antiviral immune response for therapy and vaccination by Yong, Hui Yee

“…In this thesis, the development of potent innate immune modulatory RNA (ImmRNA), capable of triggering a robust type I interferon signalling in human cells is reported. …”
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An immune-competent human gut microphysiological system enables inflammation-modulation by Faecalibacterium prausnitzii by Zhang, Jianbo, Huang, Yu-Ja, Trapecar, Martin, Wright, Charles, Schneider, Kirsten, Kemmitt, John, Hernandez-Gordillo, Victor, Yoon, Jun Young, Poyet, Mathilde, Alm, Eric J., Breault, David T., Trumper, David L., Griffith, Linda G.

“…However, there is no existing system for a long-term co-culture of human innate immune cells with epithelium and oxygen-intolerant commensal microbes, hindering the understanding of microbe-immune interactions in a controlled manner. …”
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The influence of nostalgia on serious leisure participation to achieve personal growth and happiness by Low, Shirmin Li Min

“…This study looks outside the scope of its innate characteristics and looks at how nostalgia could affect serious leisure participation, and in turn result in personal growth and happiness. 305 responses were collected from serious leisure participants through the completion of a questionnaire. …”
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Understanding liver transplantation outcomes through the lens of its tissue-resident immunobiome by Prosser, AC, Klenerman, P, Lucas, M

“…The heterogeneous TRL population spans the innate to adaptive immune continuum, with roles during normal physiology in homeostatic maintenance, tissue repair, pathogen detection, and rapid mounting of immune responses. …”