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    Characterizing the function of the Arl15 gene and its role in the development of metabolic traits by Bai, Y

    Published 2019
    “…The in vitro studies show a role for Arl15 in adipose tissue development.</p>…”
    Thesis
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    Role of Interferon-stimulated gene 15 (ISG15) in replication fork progression and PARP inhibitor resistance in cancer by Seung, Y

    Published 2024
    “…Understanding PARP (Poly-ADP ribose polymerase) inhibitor resistance is crucial in cancer therapy, particularly in treating cancers associated with BRCA mutations. The role of ISG15 (Interferon-Stimulated Gene 15) in PARP inhibitor resistance adds a layer of complexity to this phenomenon. …”
    Thesis
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    Roles of POPX2 phosphatase in the regulation of apoptosis by Weng, Ting

    Published 2015
    “…The rigidity of matrix plays crucial roles in tumorigenesis. Physical signals provided by the substrates are sensed and conveyed by focal adhesions and actin cytoskeletons to the interior of the cell to elicit responses. …”
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    Thesis
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    Role of substrate rigidity on cell migration by Poh, Si En

    Published 2017
    “…Further examination of focal adhesion protein levels, paxillin and vinculin, by Western Blot revealed inconclusive results. Hence, further studies are required to characterize the role of matrix rigidity in regulating formation of focal adhesions and cellular migration.…”
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    Final Year Project (FYP)
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    Emerging roles of downstream of kinase 3 in cell signaling by Loh, Jia Tong, Teo, Joey Kay Hui, Lim, Hong-Hwa, Lam, Kong-Peng

    Published 2020
    “…Since its discovery, considerable progress has been made toward defining the role of Dok-3 in limiting B cell-receptor signaling. …”
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    Journal Article
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    The role of POPX2 in the regulation of hippo pathway by Muhammad Bakhait Rahmat

    Published 2018
    “…The Hippo pathway has gained immense attention due to its key role in regulating organ size as well as its relevance to tissue regeneration and cancer. …”
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    Thesis
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    The role of SPRTN protease in colorectal cancer chemotherapy by Peron, C

    Published 2023
    “…In order to address this need, the role of SPRTN in colorectal cancer chemotherapy is investigated for the first time in this thesis.…”
    Thesis
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    The role played by Singlish in the lives of migrants in Singapore by You, Jing

    Published 2015
    “…To ease such tensions, integration is essential and this thesis investigates the role of Singlish, its usage and function in particular, in the lives of migrants in Singapore. …”
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    Final Year Project (FYP)
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    The role of EZH2-VAV interaction in tumorigenesis by Wong, Jong Fu

    Published 2015
    “…We have previously identified a novel cytosolic role for EZH2 in the regulation of cell signaling via interaction with VAV family proteins; whether EZH2 interactions with the VAV are critical for tumorigenesis has not been explored. …”
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    Thesis
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    Role of different dendritic cell subsets in vivo by Abdul Rashid Mohammad Muzaki

    Published 2015
    “…In a dextran sodium sulphate (DSS) model of colonic inflammation, ablation of CD103+ CD11b- colonic DCs resulted in exacerbated colitis, while ablation of colonic CD103+ CD11b+ DCs resulted in resistance to colitis when subjected to the same DSS regiment. Hence our results highlight the opposing roles of these two distinct colonic DC subsets in controlling DSS-induced colonic inflammation. …”
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    Thesis
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    Understanding the role of Enterococcus faecalis in polymicrobial wounds by Davient, Bala

    Published 2023
    “…While Enterococcus faecalis is a lactic acid bacteria frequently detected in polymicrobial chronic wounds, its role in these wounds is unclear. I was therefore motivated to understand the role of E. faecalis in polymicrobial wounds, as the knowledge will guide evidence-based personalized wound therapies, enhancing treatment effectiveness, while reducing treatment costs. …”
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    Thesis-Doctor of Philosophy
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    Investigating the role of factor inhibiting HIF (FIH) in tumourigenesis by Ma, J

    Published 2017
    “…HIF has been shown to exert broad, and sometimes controversial, effects on tumour progression through the induction of over 70 effector genes. Factor Inhibiting HIF (FIH), an oxygen-dependent hydroxylase of HIF, inhibits the transcription of selective HIF target genes, and is hence a potential therapeutic target to fine-tune HIF activity. …”
    Thesis
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    Role of Tau and NRF2 in oxidative stress responses by Ameyaw, B

    Published 2024
    “…</p> <p>b) <strong>I identified a novel role for the Microtubulin Associated Protein Tau <em>(MAPT)</em> gene in protection against oxidative stress.…”
    Thesis