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2721
Molecular recognition in protein-DNA assemblies
Published 2009“…Extensive adduct formation observed at the centre of the NCP suggests that this region of the nucleosome, known to be least accessible to protein factors, may provide a favorable target for the design of improved platinum anticancer drugs.In addition to platinum drug site selectivity studies, we engaged in biophysical and biochemical studies revealing functional aspects of chromatin-drug interactions that are shedding light on new possibilities for anticancer agent development. …”
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Research Report -
2722
Jurisdictional approaches to high conservation value area designation using regulatory instruments: an Indonesian pilot project
Published 2024“…In response, certification at a regional, ‘jurisdictional’ scale concordant with local environmental regulation has been proposed as an alternative to conventional, piecemeal certification. …”
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Journal Article -
2723
Carnobacterium maltaromaticum boosts intestinal vitamin D production to suppress colorectal cancer in female mice
Published 2024Get full text
Journal Article -
2724
Promoting mental health and educational success among young people in the Global South
Published 2024“…This article studies EMI transition policies using a longitudinal dataset from Ethiopia, leveraging regional variation in education language policy reforms for causal identification. …”
Thesis -
2725
Formulation, optimization and characterization of palm kernel oil esters nanoemulsion system containing sodium diclofenac
Published 2014“…The increase of hydrophilic lipophilic balance (HLB) value and synergism effect between the surfactants in the binary surfactants systems gave larger homogenous and isotropic phases. The isotropic region in the PKOEs/Lecithin:Cremophore EL (60:40)/water system was selected as nano-size emulsions composition range to be optimized and evaluated for their independent variables on responses of particle size and viscosity using Response Surface Methodology. …”
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Thesis -
2726
Using brain structural neuroimaging measures to predict psychosis onset for individuals at clinical high-risk
Published 2024“…The accuracy of the classifier on the training and independent confirmatory datasets was 85% and 73% respectively. Regional cortical surface area measures-including those from the right superior frontal, right superior temporal, and bilateral insular cortices strongly contributed to classifying CHR-PS+ from HC. …”
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Journal Article -
2727
考虑抗弯刚度不确定性的简支梁桥损伤定位方法 = Damage localization method for simply supported bridge with flexural stiffness uncertainty considered
Published 2015“…If the slopes of two attachment lines between one point (x2=x'+m) and its two adjacent points change, it can be known that damage occurs within the region [x',x'+m] or [l- x'- m,l- x']. In addition, the effect of damage localization can be adjusted by changing the value of load.…”
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Journal Article -
2728
Adiposity and metabolic health in Asian populations: an epidemiological study using dual-energy x-ray absorptiometry in Singapore
Published 2024“…Type 2 diabetes, cardiovascular disease, and related cardiometabolic disturbances are increasing rapidly in the Asia-Pacific region. We investigated the contribution of excess adiposity, a key determinant of type 2 diabetes and cardiovascular risk, to unfavourable cardiometabolic profiles among Asian ethnic subgroups. …”
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Journal Article -
2729
Relationship between synoptic scale meteorology, aircraft parameters, and observable contrails
Published 2024“…To perform this analysis, a dataset of 180 manually-attributed, unique contrails was created that captures regional (across the continental United States) and diurnal variation. …”
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Thesis -
2730
Pollen geochronology from the Atlantic coast of the united states during the last 500 years
Published 2021Get full text
Journal Article -
2731
A dynamic knowledge graph approach to distributed self-driving laboratories
Published 2024Get full text
Journal Article -
2732
Structural study of ribosome : 1) structural basis of EF-G in translocation. 2) molecular mechanism of ribosome-dependent toxin YoeB in mRNA cleavage
Published 2015“…Binding with the ribosome and the GTP analogue facilitate the stabilization of EF-G switch I region, resulting in an ordered model of the active site. …”
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Thesis -
2733
Surface plasmon resonance (SPR) enhanced biosensors
Published 2016“…Surface plasmons are commonly excited by external electromagnetic radiation and a common feature of plasmons are that they concentrate the field to the near surface region, and can thus be used to enhance extinction, fluorescent, Raman and other signals. …”
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Thesis -
2734
Non-invasive nanosensor monitoring of mRNA expression for regenerative medicine application
Published 2017“…Crucially, sustained release of MBs into the cytoplasmic region prolongs intracellular monitoring window of MBs, which are rapidly digested and cleared from cells otherwise. …”
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Thesis -
2735
Parallel and distributed algorithms for computational fluid flow simulations
Published 2018“…The utilization of this type of model requires the handling of an enormous amount of information, which normally involves the hydrological (spatial-temporal) characteristics, regional geographical information as well as the characteristics of the drainage system. …”
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Thesis -
2736
Sexual violence at higher education institutions: prevalence, nature, and opportunities for prevention
Published 2023“…</p> <p><strong>Method:</strong> First, I conducted a systematic review of SV prevalence studies at HEIs and meta-analysed the prevalence of SV disaggregated by gender, type of SV, and world region. Second, in collaboration with stakeholders across the University of Oxford, I developed a cross-sectional survey (the OUR SPACE survey) to measure the prevalence, nature, and context of SV at the University of Oxford. …”
Thesis -
2737
Congenital myasthenic syndromes: characterisation of a new animal model, exploring potential novel therapies and assessing the outcome of COVID-19 infection
Published 2024“…By molecular cloning and residue swapping, a region involved in the allosteric binding and its mechanism of action was narrowed down to the M2-M3 loop of the epsilon subunit.…”
Thesis -
2738
Quantifying the energy consumption of the water use cycle
Published 2017“…</p> <p>In this particular case study, the results show that there are important differences in energy consumption by region, and significant differences in the seasonal and energy patterns of water infrastructure systems. …”
Thesis -
2739
Non-contact laser-ultrasonic subsurface thermography using waveform inversion
Published 2022“…A strategy of using multiple central frequencies for joint inversion is proved to be useful due to its larger reconstruction depth and higher accuracy in the near-surface region.…”
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Thesis-Doctor of Philosophy -
2740
Malaria parasite stress tolerance is regulated by DNMT2-mediated tRNA cytosine methylation
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Journal Article