In Vivo RNA Delivery to Hematopoietic Stem and Progenitor Cells via Targeted Lipid Nanoparticles by Shi, Dennis, Toyonaga, Sho, Anderson, Daniel G

“…However, these therapies have several limitations owing to the manufacturing complexities and toxicity resulting from required conditioning regimens. Here, we developed a c-kit (CD117) antibody-targeted lipid nanoparticle (LNP) that, following a single intravenous injection, can deliver RNA (both siRNA and mRNA) to HSCs in vivo in rodents. …”
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Posture control and balance for quality of walking in rehabilitation by Li, Lei

“…A torque-driven, five segments (two thigh segments, two shank segments and one trunk segments) forward dynamics simulation model is first used to study the human posture and passive stabilizing device control. …”
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Knowledge and practice regarding medication use among elderly with chronic diseases in Felda Tembangau 2, Kemayan, Pahang by Farid, Aina Natasha Mohd

“…The elderly population, defined as those aged 60 and above, faces unique challenges in managing chronic diseases due to physiological changes, limited access to healthcare information, and barriers in understanding and adhering to medication regimens. The aim of this study was to determine the levels of knowledge and practice regarding medication use among elderly with chronic diseases in FELDA Tembangau 2, Kemayan, Pahang and to explore the correlation between these two variables. …”
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Promoting Singapore as a premier tourist destination by Koh, Hui Ling, Lim, Karen Wee Peng, Tan, Fiona Lay Choo

“…In addition , greater marketing efforts are aimed at emerging niche segments such as students, cruise and business visitors. …”
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An anatomical study to control the movement of a beetle's hind leg through electrical stimulation of muscles by Yeong, Jun Hao

“…The experimental results shows that, the muscles that control a particular segment of the leg have to reside in the previous segment and the musculature structure in the femur allows greater translating of power during walking as compared to other segments of the hind leg. …”
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Is social media really that effective for communicating budget policies to citizens? – a case study of the Singapore budget 2018 by Chin, Zhao Wei

“…Citizen feedback is collected using an online public survey, of which demographical factors such as age, educational qualifications and employment status were cross-tabulated and suggest that social media avenues such as Facebook may not be the best way to communicate budget policy to certain segments of the population. Moreover, there is a risk of investing too much focus on social media, such that other segments of the population may be neglected. …”
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Characterisation of progenitor cells in human atherosclerotic vessels by Torsney, E, Mandal, K, Halliday, A, Jahangiri, M, Xu, Q

“…In the present study, a range of normal and atherosclerotic human arteries were collected from patients undergoing coronary artery bypass surgery. Segments of internal mammary artery (normal controls), and segments of proximal ascending aorta with visible fatty streak were analysed. …”

Image analysis of swimming microorganisms by Loh, Shaun Pei Hao

“…The project consists of two major segments, mainly, flagellum profile recognition and particle tracking. …”
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Elucidating the role of metabolic changes in modulating cell fate following treatment with anti-mitotic drugs by Wong, Alex Xing Fah

“…Better understanding of the cellular pathways underlying this escape from antimitotic drug-induced cell death, known as mitotic slippage, is crucial for development of combinatorial therapies that can enhance existing treatment regimen in patients. Mitotic slippage describes a phenomenon where cells escape mitotic arrest and cell death following treatment with anti-mitotic drugs, and "slip" into interphase without proper chromosome segregation and cytokinesis. …”
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Evaluating new malaria vaccine candidates by Noé, A

“…Liver-resident memory CD8+ T cells (TRM) are necessary for protection against rodent malaria by this vaccine regimen. Ultimately, to most faithfully assess immunological responses by these local, specialised, hepatic T cells, periodic liver sampling is necessary. …”

Attractiveness of Singapore's tertiary business education to foreign students by Pang, Kah Kin, Tee, Chun Siang, Teo, Reddy Hong Joo

“…This research aims to group factors important to international students studying management education in Singapore and also investigates for significant differences between different segments of the same population.…”
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Data Analytics for Cybersecurity / by Janeja, Vandana P., 1976-, author 655477, Cambridge University Press (Online service) 655240

“…Analyzing data across different segments of cybersecurity domains, particularly data generated during cyber-attacks, can help us understand threats better, prevent future cyber-attacks, and provide insights into the evolving cyber threat landscape. …”
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Dynamic scan chains : a novel architecture to lower the cost of VLSI test by Sitchinava, Nodari S. (Nodari Shalva), 1981-

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Pathways to virality : psychophysiological responses preceding likes, shares, comments, and status updates on Facebook by Alhabash, Saleem, Almutairi Nasser, Lou, Chen, Kim, Wonkyung

“…We contrasted Facebook organic use segments that ended with pressing on the like button to those that did not end with liking the Facebook post. …”
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Synthesis of biodegradable thermoplastic elastomers based on polyurethane by Liow, Sing Shy.

“…Biodegradable thermoplastic elastomer based on polyurethanes (BTPU) were synthesized from random or triblock copolymers, with polycaprolactone (PCL) as one of the component in the soft segments (SS). 1,6-hexamethylene diisocyanate (HMDI) and 1,4-butanediol (BDO) served as hard segments (HS). …”
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Validating and valuing business models for the wireless entertainment industry. by Chee, Sow Har., Han, Hilda Mei Ian., Ho, Sarah Wei Jan.

“…The objective of this research is to examine the potential for wireless entertainment in Singapore and how it can be adapted to suit the needs of the different market segments. To find out whether there is market potential for such wireless applications, pursuance of consumer-focused research is a pre-requisite.…”
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The prevention and management of chronic kidney disease among patients with metabolic syndrome by Zhu, D, Judge, PK, Wanner, C, Haynes, R, Herrington, WG

“…In addition, statin-based regimens lower low-density lipoprotein cholesterol and reduce the risk of atherosclerotic disease (with no clinically meaningful effect on kidney outcomes). …”

Somatic gene mutation patterns and burden influence outcomes with enasidenib in relapsed/refractory IDH2-mutated AML by Risueño, A, See, WL, Bluemmert, I, de Botton, S, DiNardo, CD, Fathi, AT, Schuh, AC, Montesinos, P, Vyas, P, Prebet, T, Gandhi, A, Hasan, M

“…We recently reported results from the phase 3 IDHENTIFY trial (NCT02577406) showing improved response rates and event-free survival with enasidenib monotherapy compared with conventional care regimens (CCR) in heavily pretreated, older patients with late-stage R/R AML bearing IDH2 mutations. …”

On-line optimization of biomimetic undulatory swimming by an experiment-based approach by Zhou, Chunlin, Low, Kin Huat

“…It is also found that the propulsor with six fin segments, is preferable because of higher speed and lower energy efficiency.…”
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Genomic profiling of mycobacterium tuberculosis strains, Myanmar by Aung, Htin Lin, Nyunt, Wint Wint, Fong, Yang, Biggs, Patrick J., Winkworth, Richard C., Lockhart, Peter J., Yeo, Tsin Wen, Hill, Philip C., Cook, Gregory M., Aung, Si Thu

“…Introducing new oral drugs to replace those currently used in treatment regimens for multidrug-resistant TB will also be useful for treating TB in Myanmar.…”
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