Topology surveillance of the lanosterol demethylase CYP51A1 by signal peptide peptidase by Sergejevs, N, Avci, D, van de Weijer, ML, Corey, RA, Lemberg, MK, Carvalho, P

“…Cleavage of transmembrane segments on target proteins by the aspartyl intramembrane protease signal peptide peptidase (SPP, encoded by HM13) has been linked to immunity, viral infection and protein quality control. …”

In Vivo RNA Delivery to Hematopoietic Stem and Progenitor Cells via Targeted Lipid Nanoparticles by Shi, Dennis, Toyonaga, Sho, Anderson, Daniel G

“…However, these therapies have several limitations owing to the manufacturing complexities and toxicity resulting from required conditioning regimens. Here, we developed a c-kit (CD117) antibody-targeted lipid nanoparticle (LNP) that, following a single intravenous injection, can deliver RNA (both siRNA and mRNA) to HSCs in vivo in rodents. …”
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Knowledge and practice regarding medication use among elderly with chronic diseases in Felda Tembangau 2, Kemayan, Pahang by Farid, Aina Natasha Mohd

“…The elderly population, defined as those aged 60 and above, faces unique challenges in managing chronic diseases due to physiological changes, limited access to healthcare information, and barriers in understanding and adhering to medication regimens. The aim of this study was to determine the levels of knowledge and practice regarding medication use among elderly with chronic diseases in FELDA Tembangau 2, Kemayan, Pahang and to explore the correlation between these two variables. …”
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The truth about cats and dogs by Parkhi, O, Vedaldi, A, Jawahar, C, Zisserman, A

“…In these cases we propose to use the template-based model to detect a distinctive part for the class, followed by detecting the rest of the object via segmentation on image specific information learnt from that part. …”

Between these bones by Park, Caitlin Elizebeth, Ng, Joyce Hui Jie, Li, Jiaqi, Shridhar, Pranamika Subhalaxmi

“…Divided into three chapters, each segment explores the effects of space on different individuals. …”
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Crack densification in drying colloidal suspensions by Lilin, Paul, Ibrahim, Mario, Bischofberger, Irmgard

“…We show that the final spacing between radial cracks is proportional to the local thickness of the deposit, while the aspect ratio of the crack segments depends on the shape of the deposit.…”
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A study on the motivating factors and marketing strategies that affect donations to Singapore-based charities. by Lee, Jenevie Yu Ling., Ong, Yi Ning., Su, Han-Inn.

“…We hope fundraisers can use this knowledge to target the appropriate segment of the population. A descriptive study was conducted using research instruments such as secondary data collection, interviews and surveys. …”
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Spin carbon nanotubes into CNT fibers by Lim, Johnathan See Kwan.

“…After densifying, each strand of fiber were tested for their mechanical properties before they were divided into smaller segments and twisted together to form multi-ply fibers, ranging from a 2 ply CNT yarn to a 10 ply CNT yarn. …”
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Multi-linear regression models for traffic prediction in large-scale networks by Zhao, XinYue

“…Various methods have been practice in the traffic forecasting study and some algorithms that used in other fields like In this paper we apply 3 multi-linear regression models on the speed data collected from 266 road segments in Singapore, which are Partial Least Square, High-Order Partial Least Square and N-way Partial Least Square model. …”
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National Day parades : we the citizens of Singapore by Low, Annabel Hui Xin

“…This will be done through the examination of how three segments of the National Day parade – the military showcase, performances and National Day songs – have been used and adapted over the years to further the government’s nation building efforts in Singapore.…”
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Fine-scale population structure and widespread conservation of genetic effect sizes between human groups across traits by Hu, S, Ferreira, LAF, Shi, S, Hellenthal, G, Marchini, J, Lawson, DJ, Myers, SR

“…To estimate the similarity of genetic effect sizes between groups, we developed ANCHOR, which estimates changes in the predictive power of an existing PGS in distinct local ancestry segments. ANCHOR infers highly similar (estimated correlation 0.98 ± 0.07) effect sizes between UK Biobank participants of African and European ancestry for 47 of 53 quantitative phenotypes, suggesting that gene–environment and gene–gene interactions do not play major roles in poor cross-ancestry PGS transferability for these traits in the United Kingdom, and providing optimism that shared causal mutations operate similarly in different populations.…”

Instabilities in tidal turbine wakes by Smyth, ASM, Nishino, T, Young, AM

“…Unsteady inflow causes the turbine blades to shed vorticity of time-varying strength into the wake, which in turn leads to a spatial variation in wake vortex strength, such that the vorticity of adjacent returning wake segments can differ. This spatial variation triggers the instability of tip vortices, the characteristics of which are shown to be governed by the ’frequency ratio’ ω/ΩNB (where ω is harmonic inflow frequency, Ω is turbine rotational frequency and NB is the number of blades). …”

A new method of N to C sequential ligation using thioacid capture ligation and native chemical ligation by Hou, Wen, Liu, Lei, Zhang, Xiaohong, Liu, Chuanfa

“…Herein, we developed an alternative method which could perform the sequential peptide ligation of several segments from N to C direction based on the combined use of thioacid capture ligation and native chemical ligation. …”
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Quantitative analysis of coronary artery from computed tomography angiography images by Cui, Hengfei

“…An automatic coronary artery segmentation approach based on Hessian filter and connected components is proposed. …”
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The prevention and management of chronic kidney disease among patients with metabolic syndrome by Zhu, D, Judge, PK, Wanner, C, Haynes, R, Herrington, WG

“…In addition, statin-based regimens lower low-density lipoprotein cholesterol and reduce the risk of atherosclerotic disease (with no clinically meaningful effect on kidney outcomes). …”

Somatic gene mutation patterns and burden influence outcomes with enasidenib in relapsed/refractory IDH2-mutated AML by Risueño, A, See, WL, Bluemmert, I, de Botton, S, DiNardo, CD, Fathi, AT, Schuh, AC, Montesinos, P, Vyas, P, Prebet, T, Gandhi, A, Hasan, M

“…We recently reported results from the phase 3 IDHENTIFY trial (NCT02577406) showing improved response rates and event-free survival with enasidenib monotherapy compared with conventional care regimens (CCR) in heavily pretreated, older patients with late-stage R/R AML bearing IDH2 mutations. …”

State and faith: the supply-side theory of religion and the case of Turkey by Gurses, Mehmet, Fox, Jonathan, Öztürk, Ahmet Erdi

“…Results from a series of public opinion surveys conducted between 2010 and 2020 show that the AKP rule has caused the religious segment of Turkish society to consolidate around AKP and secular sections to consolidate around the opposition, leading to a significant polarization within the country. …”

Foreign exchange prediction and trading using low-shot machine learning by Faris Ahmad Ishak

“…This technique has been applied to image databases to further segment and create forecasting figures. In this paper, a financial dataset is converted and built into an image database of 5 feature classes. …”
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Is this a good time to invest in Panamax tankers? by Lim, Daryl Sze Hng.

“…The paper carried out historical trend analyses and evaluated the current supply and demand of Panamax tankers in the market. Also, a segment on trend indicators was analysed using the correlation coefficient method together with scatter diagrams to derive patterns between the decision to invest into a Panamax tanker and the chosen variables. …”
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Battery plug - in electric car : Vehicle chassis components design and modification by Tow, Edward

“…The future of the BEV project is discussed in the last segment.…”
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