Modular Titratable Polypills for Personalized Medicine and Simplification of Complex Medication Regimens by Karavasili, Christina, Babaee, Sahab, Kutty, Shruti, Chu, Jacqueline N., Min, Seokkee, Fitzgerald, Nina, Morimoto, Joshua, Inverardi, Nicoletta, Traverso, Giovanni

“…Simplification of complex medication regimens in polypharmacy positively contributes to treatment adherence and cost‐effective improved health outcomes. …”
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De l'arme de guerre à l'objet de collection. Une histoire matérielle des canons français d’Ancien Régime au Musée royal de Mariemont (XVIIIe-XXIe siècles) by Depreter, M

The IDentif.AI-x pandemic readiness platform: rapid prioritization of optimized COVID-19 combination therapy regimens by Blasiak, Agata, Truong, Anh T. L., Remus, Alexandria, Hooi, Lissa, Seah, Shirley Gek Kheng, Wang, Peter, Chye, De Hoe, Lim, Angeline Pei Chiew, Ng, Kim Tien, Teo, Swee Teng, Tan, Yee-Joo, Allen, David Michael, Chai, Louis Yi Ann, Chng, Wee Joo, Lin, Raymond T. P., Lye, David C., Wong, John Eu-Li, Tan, Gladys Gek-Yen, Chan, Conrad En Zuo, Chow, Edward Kai-Hua, Ho, Dean

“…A starting pool of 12 candidate drugs developed in collaboration with a community of infectious disease clinicians was first narrowed down to a six-drug pool and then interrogated in 50 combination regimens at three dosing levels per drug, representing 729 possible combinations. …”
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Telacebec (Q203)-containing intermittent oral regimens sterilized mice infected with Mycobacterium ulcerans after only 16 doses by Chauffour, Aurélie, Robert, Jérôme, Veziris, Nicolas, Aubry, Alexandra, Pethe, Kevin, Jarlier, Vincent

“…These results are very promising for future intermittent oral regimens which would greatly simplify BU treatment in the field.…”
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A mixed methods study investigating factors affecting adherence to Plasmodium vivax malaria primaquine radical cure regimens among migrants along the Myanmar-Thailand border by Ansari, AT, Aung, KK, Win, HH, Beau, C, Nu, B, Soe, NL, Htoo, K, San, T, Wah, TG, Keereevijit, A, Phyo, AP, Chotivanich, K, White, NJ, Nosten, F, Hashmi, AH, Chu, CS

“…Understanding and facilitating adherence to primaquine radical cure regimens is necessary for malaria elimination. Methods: A convergent parallel mixed methods study was conducted to investigate the barriers to and facilitators for completing primaquine treatment of P. vivax infection among mobile migrant communities on the Myanmar-Thailand border. …”

Overall survival by IDH2 mutant allele (R140 or R172) in patients with late-stage mutant- IDH2 relapsed or refractory acute myeloid leukemia treated with enasidenib or conventional care regimens in the phase 3 IDHENTIFY trial by De Botton, S, Risueño, A, Schuh, AC, Lowenberg, B, Kim, H-J, Vyas, P, Wei, AH, Stein, EM, Dohner, H, Fathi, AT, Dinardo, CD, Martin Regueira, P, Taningco, L, Bluemmert, I, Yu, X, See, WL, Hasan, M

Deliberation in the Russian state Duma: from a seat of discussion to a tool of autocracy, 1996-2021 by James, N

“…Why do legislators continue to engage in parliamentary floor activities under authoritarian regimes when policy decisions and voting outcomes are often predetermined before reaching the debate stage? …”

Droplet impact on superheated surfaces by Khavari, Mohammad

“…The former case is commonly referred to as the contact boiling regime, while the latter one is known as the Leidenfrost regime. …”
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Asymptotic analysis of deep residual networks by Cont, R, Rossier, A, Xu, R

“…We first show the existence of scaling regimes for trained weights markedly different from those implicitly assumed in the neural ODE literature. …”

Varieties of indoctrination: the politicization of education and the media around the world by Neundorf, A, Nazrullaeva, E, Northmore-Ball, K, Tertytchnaya, KT, Kim, W

“…For many decades, scholars assumed voluntary compliance and citizens’ commitment to a regime’s principles and values to be critical for regime stability. …”

Forces on oscillating uniform and tapered cylinders in a crossflow by Hover, F. S., Techet, A. H., Triantafyllou, M.S.

“…Calculation of the cross-correlation coefficient between forces at the two ends of the uniform cylinder reveals five distinct regimes as a function of the nominal reduced velocity Vrn: two regimes, for low and high values of Vrn, and far away from the value of VrS corresponding to the Strouhal frequency, show small correlation; two regimes immediately adjacent to, but excluding, VrS show strong correlation, close to 1; surprisingly, there is a regime containing the Strouhal frequency, within which correlation is low. …”
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Laser-induced reduced-graphene-oxide micro-optics patterned by femtosecond laser direct writing by Low, Mun Ji, Lee, Hyub, Lim, Joel Chin Huat, Suchand Sandeep, Chandramathi Sukumaran, Murukeshan, Vadakke Matham, Kim, Seung-Woo, Kim, Young-Jin

“…By extensive parametric control of average power (10–120 mW), pulse repetition rate (1–500 kHz) and scan speed (1–100 mm/s) in FsLDW, ultra-thin micro-optics were patterned at three patterning regimes: non-thermal photoreduction regime, thermal photoreduction regime, and ablation regime. …”
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Spontaneous Symmetry Breaking in a Polariton and Photon Laser by Ohadi, H., Kammann, E., Liew, Timothy Chi Hin, Lagoudakis, K. G., Kavokin, A. V., Lagoudakis, P. G.

“…We report on the simultaneous observation of spontaneous symmetry breaking and long-range spatial coherence both in the strong- and the weak-coupling regime in a semiconductor microcavity. Under pulsed excitation, the formation of a stochastic order parameter is observed in polariton and photon lasing regimes. …”
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No Shangri-La for North Korea by Samaniego, Catherine

“…Kim Jong-un should expect to see his regime’s political leverage in Northeast Asia gradually reduced, while its biggest ally, China, remains preoccupied with its own domestic concerns.…”
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Criteria for Crack Formation and Air Invasion in Drying Colloidal Suspensions by Lilin, Paul, Bischofberger, Irmgard

“…We show that the pressure inside the deposit controls both the onset of crack formation and the onset of air invasion. Two distinct regimes of air invasion occur, which we can account for using the same model that further provides a quantitative criterion for the crossover between the two regimes.…”
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The effect of salt on oligocation-induced chromatin condensation by Korolev, Nikolay, Zhao, Yongqian, Allahverdi, Abdollah, Eom, Khee Dong, Nordenskiöld, Lars, Tam, James P.

“…In the salt-dependent regime EC50 rises sharply with increase of CKCl. Increase of ligand charge shifts the transition from the salt-independent to salt-dependent regime to higher salt. …”
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Origin of residual strain in heteroepitaxial films by Postelnicu, Eveline, Wen, Rui-Tao, Ma, Danhao, Wang, Baoming, Wada, Kazumi, Michel, Jurgen, Kimerling, Lionel C

“…The model is expressed in terms of three regimes: (1) misfit control for the low temperature growth regime at 400 °C; (2) point defect control via annealing in the point defect recovery regime at 500–650 °C; and (3) thermal expansion control for growth or anneal at T > 650 °C in the dislocation recovery regime. …”
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Dynamics of the sub-Ohmic spin-boson model : a comparison of three numerical approaches by Yao, Yao, Duan, Liwei, Lü, Zhiguo, Wu, Chang-Qin, Zhao, Yang

“…In order to probe the validity regimes of the three approaches, we study the dynamics of a qubit coupled to a bosonic bath with and without a local field. …”
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Prediction and prevention of disproportionally dominant agents in complex networks by Lera, Sandro Claudio, Pentland, Alex, Sornette, Didier

“…We derive an exact four-dimensional phase diagram that separates the growing system into two regimes: one where the “fit get richer” and one where, eventually, the WTA. …”
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Assessment of novel pre-erythrocytic malaria vaccines in humans by Venkatraman, N

“…ChAd63-MVA ME-TRAP is a regime that has been developed in the Jenner Institute and the first of the clinical trials described in Chapter 3 assesses the safety and immunogenicity of adjuvanting this regime with a novel saponin-based adjuvant, Matrix-M^TM. …”