REST targets JAK–STAT and HIF-1 signaling pathways in human Down syndrome brain and neural cells by Huang, Tan, Fakurazi, Sharida, Cheah, Pike-See, Ling, King-Hwa

“…We found that REST-targeted DEGs in DS were enriched for the JAK–STAT and HIF-1 signaling pathways across multiple distinct brain regions, ages, and neural cell types. We also identified REST-targeted DEGs involved in nervous system development, cell differentiation, fatty acid metabolism and inflammation in the DS brain. …”
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Meta-analysis and moderator analysis of the seroprevalence of hepatitis E in South Eastern Asia by Raji, Yakubu Egigogo, Toung, Ooi Peck, Mohd Taib, Niazlin, Sekawi, Zamberi

“…The high HEV prevalence found in this study necessitates coordinated national and regional efforts to combat this emerging disease.…”
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Analysis of the effects of density profile on the bending properties of particleboard using finite element method (FEM) by Wong, E.-D., Yang, P., Zhang, M., Wang, Q., Nakao, T., Li, K.-F., Kawai, S.

“…Increment in peak density (PD) results in a proportional increase in MOE, while core density (CD) determines the optimum slope gradient between the peak and core regions. 3. The counteractive effect arising from increment in PD and simultaneous reduction in peak width resulted in merely 9% improvement in MOE, when PD was increased from 1.0 to 1.5 g/cm3. 4. …”

Unveiling the impacts of climate change and human activities on land-use evolution in ecologically fragile urbanizing areas: a case study of China's Central Plains Urban Agglomerat... by Jiang, Zhimeng, Li, Yan, Wu, Hao, Mohamed Shariff, Abdul Rashid, Zhou, Han, Fan, Kaixuan

“…Our results reveal that environmental changes significantly influence the spatiotemporal evolution of land use, accelerating rural-to-urban conversions in ecologically vulnerable regions, as validated by a CA-Markov model Kappa coefficient of 0.8378. …”
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An immunoinformatic approach for identifying and designing conserved multi-epitope vaccines for coronaviruses by Ong, Yu Chuan, Tejo, Bimo Ario, Yap, Wei Boon

“…Their peptide sequences were then aligned and assembled to identify the overlapping regions. Eventually, two major peptide assemblies were derived based on their promising immune-stimulating properties. …”
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Airborne microplastic/nanoplastic research: a comprehensive Web of Science (WoS) data-driven bibliometric analysis by Tan, Huiyi, Mong, Guo Ren, Wong, Syie Luing, Wong, Keng Yinn, Sheng, Desmond Daniel Chin Vui, Nyakuma, Bemgba Bevan, Othman, Mohd Hafiz Dzarfan, Kek, Hong Yee, Abdull Razis, Ahmad Faizal, Abdul Wahab, Nur Haliza, Abdul Wahab, Roswanira, Lee, Kee Quen, Chiong, Meng Choung, Lee, Chia Hau

“…China, England, the USA, and European Countries have produced a significant output of airborne MP/NP research works, which is associated with the availability of funding agencies regionally or nationally. The research hotspot on the topic ranges from the transport of airborne MPs/NPs to their deposition in the terrestrial or aquatic environments, along with the contamination of samples by indoor MPs/NPs. …”

Breast cancer diagnosis through an optimization-driven multispectral gamma correction (ODMGC) by Raj A, Arul Edwin, Ahmad, Nabihah, Durai S, Ananiah

“…Then, based on the grey levels of the pixels, we grouped each categorisation into sub-regions. Followed by each group has undergone individually optimised base enhancement. …”
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Mapping of sentiment analysis on food security among Malaysians using social media analytics by Rusli, Noradila, Lee, Yoke Lai, Rosley, Muhamad Solehin Fitry, Lee, Cher Enn, Hamzah, Maheran, Alias, Nurul Ezaila, Bahari, Noraini, Mamat, Mohd. Razif

“…Pre-processing and content analysis techniques identified the main themes in the tweets, while sentiment analysis categorised them using VADER: ArcGIS and hotspot analysis visualised and analysed tweet density. Regional trends were observed, with the East Coast states and certain West Coast states having the highest number of tweets. …”
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Comparison of Credit Risk Management Practices among Islamic and Public Commercial Bank’s in Pakistan by Iqbal, Muhammad Saeed, Sofi, Mohd Fikri

“…It is concluded that this study results may help the banks to find the solutions that enable quality loan creation and growth as well as to determine the relationship among the theories, concepts, of credit score and credit policies both at country level and regional level. Hence, this study is assumed to be significant in indicating best practices and concept for practical lending to enhance the performance of credit management to all mangers and policy makers of the banks as well as to all financial institutions and banks…”
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Synthesizing photorealistic images with deep generative learning by Zheng, Chuanxia

“…Part 2 presents approaches that generate semantically reasonable content for masked regions. Instead of purely modifying the local appearance as in Part 1, two approaches are presented to create new content as well as realistic appearance for a given image. …”
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Effect of Madden Julian oscillation on convectively coupled equatorial waves by Dobriyal, Ritvik

“…MJO is also found to affect CCEW over Africa and near South America if wave activity peaks in these regions, however the effect is nearly half as strong or weaker. …”
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Fabrication and characterization of protein-based tissue scaffold by Ko, Kok Wei.

“…And the spectra recorded from the structural analysis indicated the presence of secondary structures (α-helices and β-sheets) in amide I, II, III regions of protein. The SF scaffolds were tested for cytotoxicity towards the growth and morphology of fibroblast cells. …”
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Design and modelling of microgrid by Vadlamudi Sai Datta Venkateshwara Rao

“…Microgrids are low voltage networks, designed to deliver energy to relatively smaller areas rather than massive regions. The coordinated control of generation sources with presumably contradictory requirements, limited communication and significantly high transmission losses enforces the adoption of distributed intelligence techniques. …”
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Comparative evaluation of spatiotemporal methods for effective dengue cluster detection with a case study of national surveillance data in Thailand by Rotejanaprasert, C, Chinpong, K, Lawson, AB, Maude, RJ

“…Dengue fever poses a significant public health burden in tropical regions, including Thailand, where periodic epidemics strain healthcare resources. …”

Shale oil in Russia – commercial catalyst required by Henderson, J

“…To this end, the Russian authorities have been encouraging the country’s major oil companies to explore new greenfield regions – such as East Siberia, the Black and Barents Seas, and the Arctic offshore – in the hope that major new production areas can be developed. …”

Mapping the extent and exploring the drivers of cocoa agroforestry in Nigeria, insights into trends for climate change adaptation by Koralewicz, A, Vlcek, J, Oliveras-Menor, I, Hirons, M, Akinyugha, A, Sikiru Olowoyo, O, Oluyemi, M, Owen, O

“…This research can contribute to improved monitoring of cocoa-driven tree loss and provide important context for policy and program design to enhance climate change adaptation in similar cocoa producing regions.…”

Systematic assessment of COVID-19 host genetics using whole genome sequencing data by Schmidt, A, Casadei, N, Brand, F, Demidov, G, Vojgani, E, Abolhassani, A, Aldisi, R, Butler-Laporte, G, DeCOI host genetics group, Alawathurage, TM, Augustin, M, Bals, R, Bellinghausen, C, Berger, MM, Bitzer, M, Bode, C, Boos, J, Brenner, T, Cornely, OA, Eggermann, T, Erber, J, Feldt, T, Fuchsberger, C, Gagneur, J

“…Burden testing in the largest population subgroup (i.e., Europeans) suggested nominal enrichments of rare variants in coding and non-coding regions of interferon immune response genes in the overall analysis and male subgroup. …”

Investigating factors contributing to enhancer-promoter interaction by Cornell, LJ

“…Enhancer promoter interactions usually occur within topologically associated domains (TADs); large regions (200-2000kb) of interacting chromatin delimited by binding sites for the insulating factor CTCF. …”

Accessing inclusive well-being to leave no one behind by Seth, S, Alkire, S

“…We examine the inclusiveness of multidimensional well-being changes for 75 developing countries across six geographic regions. We observe robust improvements in well-being levels for most countries, but only around three-fifths of these countries overall have positive robust inclusivity premiums, and fewer than one-third in sub-Saharan Africa. …”

Revolutionizing treatment for disorders of consciousness: a multidisciplinary review of advancements in deep brain stimulation by Yang, Y, Cao, T, He, S, Wang, L, He, Q, Fan, L, Huang, Y, Zhang, H, Wang, Y, Dang, Y, Wang, N, Chai, X, Wang, D, Jiang, Q, Li, X, Liu, C, Wang, S

“…The mesocircuit model hypothesis suggests that DOC arises from disruptions in a critical network of brain regions, providing a framework for refining DBS targets. …”