Identification of a novel mitochondria-localized LKB1 variant required for the regulation of the oxidative stress response by Tan, Ivan, Xu, Shengli, Huo, Jianxin, Huang, Yuhan, Lim, Hong-Hwa, Lam, Kong-Peng

“…The tumor suppressor Liver Kinase B1 (LKB1) is a multifunctional serine/threonine protein kinase that regulates cell metabolism, polarity, and growth and is associated with Peutz-Jeghers Syndrome and cancer predisposition. …”
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Design of a thyristor-switched capacitor type voltage regulator of a self-exited induction generation by Oun, Chuan Teck.

“…Voltage regulators are widely used in the transmission network because it is a reliable and feasible solution for maintaining the voltage within a required voltage range. …”
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Supported Lipid Bilayer Platform To Test Inhibitors of the Membrane Attack Complex: Insights into Biomacromolecular Assembly and Regulation by Yorulmaz, Saziye, Jackman, Joshua Alexander, Hunziker, Walter, Cho, Nam-Joon

“…Taken together, the findings in this study outline a biomimetic approach based on supported lipid bilayers to explore the interactions between complement proteins and inhibitors, thereby offering insight into MAC assembly and regulation.…”
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Regulation of Burkholderia cenocepacia biofilm formation by RpoN and the c-di-GMP effector BerB by Fazli, Mustafa, Rybtke, Morten, Steiner, Elisabeth, Weidel, Elisabeth, Berthelsen, Jens, Groizeleau, Julie, Bin, Wu, Zhi, Boo Zhao, Yaming, Zhang, Kaever, Volkhard, Givskov, Michael, Hartmann, Rolf W., Eberl, Leo, Tolker-Nielsen, Tim

“…Knowledge about the molecular mechanisms that are involved in the regulation of biofilm formation is essential for the development of biofilm‐control measures. …”
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Transphobia as a weapon of war: reporting on Russia’s trans community amidst heightened regulation, censorship and propaganda by Sloane, Wendy

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Proteomic and metabolomic analyses of the human adult myocardium reveal ventricle-specific regulation in end-stage cardiomyopathies by Hunter, B, Li, M, Parker, BL, Koay, YC, Harney, DJ, Pearson, E, Cao, J, Chen, GT, Guneratne, O, Smyth, GK, Larance, M, O’Sullivan, JF, Lal, S

“…Constituents of gluconeogenesis, glycolysis, lipogenesis, lipolysis, fatty acid catabolism, the citrate cycle and oxidative phosphorylation were down-regulated in the left ventricle, while glycogenesis, pyruvate and ketone metabolism were up-regulated. …”

Nuclei sorting-based genome-wide CRISPR screens to identify novel regulators of hepatic insulin signalling by Martin Perez, E

“…Hence, hepatic insulin action provides an important layer of regulation in the maintenance of whole-body metabolic homeostasis, and its dysregulation is closely associated with metabolic disease progression. …”

The need for regulation: permissive governance and disproportionate use of live facial recognition technology by the Metropolitan Police Service by Croker, JT

“…The conclusions reached in this thesis call for appropriate and effective regulation and oversight of police use of LFR to ensure rights are protected from unlawful and disproportionate harm.…”

Effects of hormonal regulation on cell number and cell size in determining fruit size: a mini-review by Siti Khadijah A. Karim, Zamri Zainal, Nik Marzuki Sidik

“…By providing a fundamental understanding of how fruit size is regulated in plants, the process of cell number production followed by the increase of cell size has been widely studied. …”
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A comparison of preterm and full-term infant emotional regulation development through infant-mother affect synchrony by Low, Heather Yee Theng

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Energy level alignment regulation and carrier management in perovskite solar cells with various bandgaps using tailored metal-organic frameworks by Xiao, Bo, Zhang, Wenguang, Xiong, Yuchen, Huang, Yihuai, Huang, Changkai, Qian, Yongxin, Shen, Guibin, Basit, Abdul, Luo, Yubo, Li, Xin, Yang, Junyou

Subjects: “…Energy level alignment regulation…”
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Guiding transition metal-doped hollow cerium tandem nanozymes with elaborately regulated multi-enzymatic activities for intensive chemodynamic therapy by Dong, Shuming, Dong, Yushan, Liu, Bin, Liu, Jing, Liu, Shikai, Zhao, Zhiyu, Li, Wenting, Tian, Boshi, Zhao, Ruoxi, He, Fei, Gai, Shili, Xie, Ying, Yang, Piaoping, Zhao, Yanli

“…This work presents a powerful paradigm to achieve intensive NCDT efficacy by simultaneously regulating multi-enzymatic activities of Ce-based nanozymes and perturbing the H2O2 homeostasis in tumor microenvironment.…”
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Regulation of mRNA abundance by polypyrimidine tract-binding protein-controlled alternate 5′ splice site choice by Hamid, Fursham M., Makeyev, Eugene V.

“…How alternate splice sites are selected by the splicing machinery and how AS is integrated into gene regulation networks remain important questions of eukaryotic biology. …”
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A low noise, 1.28µA quiescent regulator with broadband high PSR for micropower sensors by Chan, Pak Kwong, Ong, G. T.

“…An ultra-low power, low-noise, high power supply rejection (PSR) op-ampless regulator is presented in this paper. It uses a native composite power transistor plus a sandwich on-chip native capacitor in the pre-regulator to enhance broadband high PSR performance. …”
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Treatment with siRNAs is commonly associated with GPX4 up-regulation and target knockdown-independent sensitization to ferroptosis by von Mässenhausen, Anne, Schlecht, Marlena Nastassja, Beer, Kristina, Maremonti, Francesca, Tonnus, Wulf, Belavgeni, Alexia, Gavali, Shubhangi, Flade, Karolin, Riley, Joel S., Zamora Gonzalez, Nadia, Brucker, Anne, Becker, Jorunn Naila, Tmava, Mirela, Meyer, Claudia, Peitzsch, Mirko, Hugo, Christian, Gembardt, Florian, Angeli, Jose Pedro Friedmann, Bornstein, Stefan R., Tait, Stephen W. G., Linkermann, Andreas

“…In contrast, MAVS mediated a noncanonical signal resulting in a prominent increase in mitochondrial ROS levels, and increase in the BACH1/pNRF2 transcription factor ratio and GPX4 up-regulation, which was associated with a 50% decrease in intracellular glutathione levels. …”
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Media regulation in Singapore : empirical study of the instruments of media policy and its efficiency with regard to the attainment of political objectives by Carsten, Gäbel

“…Singapore's government justifies the regulation and control of the media by drawing on the “Developmental Concept”, a variation of authoritarian media theory that delineates the role of the media in developing countries. …”
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N6-Methyladenosine: a conformational marker that regulates the substrate specificity of human demethylases FTO and ALKBH5 by Zou, Shui, Toh, Joel D. W., Wong, Kendra H. Q., Gao, Yong-Gui, Hong, Wanjin, Woon, Esther C. Y.

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Importance of miRNA stability and alternative primary miRNA isoforms in gene regulation during Drosophila development by Zhou, Li, Lim, Mandy Yu Theng, Kaur, Prameet, Saj, Abil, Bortolamiol-Becet, Diane, Gopal, Vikneswaran, Tolwinski, Nicholas, Tucker-Kellogg, Greg, Okamura, Katsutomo

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Two models of dark triad traits and self-regulation dilemma predicting IP theft through self-deception by Yeo, Diana Mui Kheng

“…This study aimed to examine how dark triad personality traits and self-regulation dilemma is related to intellectual property (IP) theft. …”
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Epigenetic drug screening identifies enzyme inhibitors A-196 and TMP-269 as novel regulators of sprouting angiogenesis by Beter, M, Pulkkinen, HH, Örd, T, Sormunen, A, Kilpeläinen, L, Dunford, JE, Kaikkonen, MU, Aavik, E, Laham-Karam, N, Oppermann, U, Laakkonen, JP, Ylä-Herttuala, S

“…We identified two epigenetic enzyme inhibitors as novel regulators of sprouting angiogenesis: A196, a selective SUV4-20H1/H2 inhibitor, demonstrated pro-angiogenic effects through increased H4K20me1 levels and upregulation of cell cycle associated genes, including MCM2 and CDK4. …”