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101
ETS2 regulation of tissue size in early mouse embryogenesis
Published 2019“…Pharmacological activation of the WNT/β-CATENIN pathway in WT recapitulated the mutant AVE phenotype, supporting scRNA-seq results. 2C-HR-CRIPSR mediated misexpression of candidate WNT agonists in the VE of WT embryos was attempted to verify whether the novel ETS2-WNT axis of AVE tissue size regulation is relevant <em>in vivo</em>. Overall, I have demonstrated the opposing effects of ETS2 on tissue size in early mouse embryogenesis: ETS2 protects the peri-implantation ExE from apoptosis, while dampens WNT/β-CATENIN signalling in the AVE to prevent overproliferation and maintain simple epithelial integrity.…”
Thesis -
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105
Regulation of the hif-1-dependent hypoxic stress response by C. elegans
Published 2024“…In almost all metazoans, oxygen is both sensed and regulated by the HIF-1 (hypoxia inducible factor) transcription factor that is activated in periods of hypoxia and goes on to regulate hundreds of genes allowing for appropriate adaptations to hypoxia. …”
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Thesis -
106
The effects of regulation on the level of voluntary corporate governance disclosure and its determinants.
Published 2008“…The effect of the regulation on the determinants of corporate governance disclosure is also examined.…”
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Final Year Project (FYP) -
107
In vitro reconstitution of liquid-liquid phase separation in regulating gene transcription
Published 2020Get full text
Final Year Project (FYP) -
108
An ultra-low supply low dropout regulator for internet-of-things applications
Published 2021“…Besides, the simulated line regulation is 1.63μV/mV and load regulation is 0.073mV/mA. …”
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Thesis-Master by Coursework -
109
Optimal distributed control for secondary frequency and voltage regulation in an islanded microgrid
Published 2021Subjects: Get full text
Journal Article -
110
Thermochromic smart windows with highly regulated radiative cooling and solar transmission
Published 2022“…Compared with current smart window technology solely regulating solar transmission and other RC materials with fixed emissivity, the TET smart window panel gives a wide tunability in the selective solar spectrum for dynamic climate conditions in energy-saving buildings, achieving largely enhanced energy saving performance globally.…”
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Journal Article -
111
ZAP isoforms regulate unfolded protein response and epithelial- mesenchymal transition
Published 2023“…We showed that the ZAP isoforms regulated different UPR branches under resting and stress conditions and affected cell viability during ER stress. …”
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Journal Article -
112
Comparing EU and UK approaches towards AI regulation: lessons for Singapore
Published 2024Subjects: Get full text
Final Year Project (FYP) -
113
The model of norm-regulated responsibility for proenvironmental behavior in the context of littering prevention
Published 2024“…These findings were consistent with several hypotheses constituting the model of norm-regulated responsibility, a novel explanatory framework offering new insights and a more nuanced and comprehensive understanding of social norms' influence on proenvironmental behavior.…”
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Journal Article -
114
Epigenetic regulation of gene expression in human malaria parasite Plasmodium falciparum.
Published 2011“…Plasmodium falciparum is the most lethal species of the Plasmodium genus. Epigenetic regulation is one of the key regulations that enable parasites to perform rapid transitions throughout their lifecycle and antigenic variations to sustain chronic infections. …”
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Final Year Project (FYP) -
115
Structural features that affect β2 integrin expression and regulation of adhesion
Published 2013“…It is established that integrin activation is regulated by the divalent cations. However, Mg2+/EGTA (5 mM Mg2+ and 1.5 mM EGTA) had been shown to promote αLβ2 adhesion to ICAM-1 but not αMβ2 adhesion to denatured BSA. …”
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Thesis -
116
Supported lipid bilayer platforms for investigating complement activation, termination and regulation
Published 2017“…In this thesis, the objective is to explore how lipid membranes influence the initiation, amplification, termination and regulation of complement activation, utilizing supported lipid bilayer platforms as a model experimental system. …”
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Thesis -
117
Anionic regulated cobalt phosphosulfide with enhanced activity for hydrogen evolution reaction
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Final Year Project (FYP) -
118
p27 is regulated independently of Skp2 in the absence of Cdk2
Published 2016“…Our findings point towards novel and alternate pathways for p27 regulation.…”
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Journal Article -
119
The Long Noncoding RNA RMST Interacts with SOX2 to Regulate Neurogenesis
Published 2016“…These results establish the role of RMST as a transcriptional coregulator of SOX2 and a key player in the regulation of neural stem cell fate.…”
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Journal Article -
120
Exploring the regulation of myofilament function in the heart using experimental and computational approaches
Published 2024“…PDE4 was found to regulate cAMP at TNI but not the MYBPC site. PKA RIα and RIIβ were found to undergo condensation in cardiomyocytes. …”
Thesis