15.021J / 11.433J Real Estate Economics, Spring 2004 by Wheaton, William C., 1944-

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Poggers in the chat : an analysis of in-group communication on Twitch by Tay, Debbie Si Ting

“…In addition to being a popular video streaming site, users of Twitch have formed their own in-group communication model exclusive to those who are regulars of the site. An integral aspect of this model is Twitch emotes, expressions of various reactions that have been so effective and popular that usage of this niche lexicon has gone past chatspeak and found its way into verbal speech. …”
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The zinc-finger transcription factor Blimp1/Prdm1 is required for uterine remodelling and repair in the mouse by Xypolita, M, Goolam, M, Bikoff, EK, Robertson, EJ, Mould, AW

“…The zinc finger transcription factor Blimp1/PRDM1 regulates gene expression in diverse cell types. Its activity controls the maternal decidual response at early post-implantation stages of development. …”

Mitogenic activity of mesenchymal stem cells on hematopoietic stem cells via cellular analysis and gene expression by Mohadeseh, Hashem Boroojerdi

“…Important genes that involve in controlling the number of HSC such as self-renewal related signaling pathway regulator genes cell cycle and apoptosis regulator genes were categorized by online DAVID software. …”
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Antifungal drug itraconazole targets VDAC1 to modulate the AMPK/mTOR signaling axis in endothelial cells by Head, Sarah A., Shi, Wei, Zhao, Liang, Gorshkov, Kirill, Pasunooti, Kalyan, Chen, Yue, Deng, Zhiyou, Li, Ruo-jing, Shim, Joong Sup, Tan, Wenzhi, Hartung, Thomas, Zhang, Jin, Zhao, Yingming, Colombini, Marco, Liu, Jun O.

“…Previous mechanistic studies have shown that itraconazole inhibits the mechanistic target of rapamycin (mTOR) signaling pathway, which is known to be a critical regulator of endothelial cell function and angiogenesis. …”
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Chromosome integrity : a major determinant of mitotic cell death in cancer treatment by Lai, Soak Kuan

“…Here, a novel molecular event that regulates mitotic cell death is reported. During prolonged mitotic arrest, caspase-3 is activated and it cleaves condensin I subunit, Cap-H. …”
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Understanding the role of transporters and ion channels in lysosomal homeostasis by Salphati, S

“…Cellular activity is regulated based on a range of cues to maintain homeostasis. …”

Rapid modulation of striatal cholinergic interneurons and dopamine release by satellite astrocytes by Stedehouder, J, Roberts, B, Raina, S, Bossi, S, Liu, AKA, Doig, N, McGerty, K, Magill, P, Parkkinen, L, Cragg, S

“…Astrocytes in striatum can regulate dopamine transmission by governing the extracellular tone of axonal neuromodulators, including GABA and adenosine. …”

Opportunity for genome engineering to enhance phosphate homeostasis in crops by Abdullah, Siti Nor Akmar, Ariffin, Norazrin, Md Hatta, Muhammad Asyraf, Kemat, Nurashikin

“…Plants maintain cellular homeostasis of phosphate (Pi) through an integrated response pathway regulated by diferent families of transcription factors including MYB, WRKY, BHLH, and ZFP. …”

Critical role for cold shock protein YB-1 in cytokinesis by Mehta, Sunali, Algie, Michael, Al-Jabry, Tariq, McKinney, Cushla, Kannan, Srinivasaraghavan, Verma, Chandra Shekhar, Ma, Weini, Zhang, Jessie, Bartolec, Tara K., Masamsetti, V. Pragathi, Parker, Kim, Henderson, Luke, Gould, Maree L., Bhatia, Puja, Harfoot, Rhodri, Chircop, Megan, Kleffmann, Torsten, Cohen, Scott B., Woolley, Adele G., Cesare, Anthony J., Braithwaite, Antony

“…Our results establish phosphorylated YB-1 as a critical regulator of cytokinesis, defining precisely how YB-1 regulates cell division.…”
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A critique of the use of species and below-species taxonomic terms for viruses—time for change? by Simmonds, P

“…The International Committee for the Taxonomy of Viruses (ICTV) regulates assignment and names of virus species and higher taxa through its taxonomy proposal and ratification process. …”

An RRM–ZnF RNA recognition module targets RBM10 to exonic sequences to promote exon exclusion by Collins, Katherine M., Kainov, Yaroslav A., Christodolou, Evangelos, Ray, Debashish, Morris, Quaid, Hughes, Timothy, Taylor, Ian A., Makeyev, Eugene V., Ramos, Andres

“…RBM10 recognizes a diverse set of RNA motifs in introns and exons and regulates alternative splicing. However, the molecular mechanisms underlying this seemingly relaxed sequence specificity are not understood and functional studies have focused on 3΄ intronic sites only. …”
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Development of quorum-sensing circuits for metabolic flux control in Escherichia coli by Dinh, Christina V.

“…This thesis aims to develop autonomous and pathway-independent regulation tools that can be applied to controlling metabolic fluxes in these contexts to improve production. …”
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BswR controls bacterial motility and biofilm formation in Pseudomonas aeruginosa through modulation of the small RNA RsmZ by Wang, Chao, Ye, Fuzhou, Kumar, Veerendra, Gao, Yong-Gui, Zhang, Lian-Hui

“…Pseudomonas aeruginosa relies on cell motility and ability to form biofilms to establish infections; however, the mechanism of regulation remains obscure. Here we report that BswR, a xenobiotic response element-type transcriptional regulator, plays a critical role in regulation of bacterial motility and biofilm formation in P. aeruginosa. …”
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Role of N-WASP in cell proliferation : implication for organ development and cancer by Verma, Apoorva

“…N-WASP regulates actin cytoskeleton and plays key roles in many cellular processes such as cell-proliferation, cell-adhesion, cell-migration and endocytosis which are essential for normal cell physiology. …”
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Targeting TFEB and TFE3 in iPSC-derived dopaminergic neurons to correct autophagic/lysosomal deficits in Parkinson's disease by McGuinness, W

“…</p> <p>Activation of cellular catabolism by targeting master regulators of lysosomal biogenesis, TFEB and TFE3 is an attractive therapeutic strategy in PD. …”

NMR structure, dynamics and interactions of the integrin β2 cytoplasmic tail with filamin domain IgFLNa21 by Chatterjee, Deepak, Tan, Suet-Mien, Bhattacharjya, Surajit, Lu, Lewis Zhiping

“…The actin-binding cytoskeletal protein filamin A is a negative regulator of integrin activation. The IgFLNa21 domain of filamin A binds to the C-terminus of β2 CT that contains a TTT-motif. …”
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Ultra low quiescent current slew rate enhanced OCL-LDO by Chua, Jocelyn Shin Hun

“…A high slew-rate amplifier is proposed in the Ultra-Low Quiescent Current Slew-Rate Enhanced OCL-LDO regulator design with improved transient response, using push-pull output to enhance driving capability that only requires ultra-low quiescent current (IQ ~1μA ). …”
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REST targets JAK–STAT and HIF-1 signaling pathways in human Down syndrome brain and neural cells by Huang, Tan, Fakurazi, Sharida, Cheah, Pike-See, Ling, King-Hwa

“…The transcription repressor, Repressor Element-1 Silencing Transcription factor (REST), which acts as an epigenetic regulator, is a crucial regulator of neuronal and glial gene expression. …”
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[Retracted] Peroxisome proliferator-activated receptor β/δ induces myogenesis by modulating myostatin activity by Bonala, Sabeera, Lokireddy, Sudarsanareddy, Arigela, Harikumar, Teng, Serena, Wahli, Walter, Sharma, Mridula, McFarlane, Craig, Kambadur, Ravi

“…Although PPARβ/δ has been implicated in regulating myogenesis, little is presently known about the role and, for that matter, the mechanism(s) of action of PPARβ/δ in regulating postnatal myogenesis. …”
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