The 2-dimensional to 3-dimensional growth transition in Physcomitrium patens by Weeks, Z

“…Therefore, 3D growth is a pivotal and unifying feature of all land plants, but we know little about how it is regulated. The model moss <em>Physcomitrium patens</em> has been developed as a model system in which to dissect the genetic basis of 3D growth, which also involves complex auxin-cytokinin crosstalk. …”

Molecular pathways leading to sleep and wakefulness in Drosophila by Christodoulou, K

“…As cv-c encodes for a Rho GTPase-activating protein (Rho-GAP) and small GTPases are often regulated by neurotrophin-related pathways, sleep induction involving the Cv-c-Sandman pathway may further couple to the upstream action of neurotrophic molecules.…”

Unveiling potential therapeutic targets for breast cancer recurrence: differentially expressed genes and pathways in post-surgery patients by Hamad, Hamad Ali, Saeed, Hammad Khalaf, Hussein, Talib Hammad, Hussain, Abdalwahab Bdewi, Md Hashim, Nur Fariesha

“…Moreover, the identified key hub genes (COL1A1, IGF1, COL1A2, DCN, LUM, MMP2, JUN, CXCL12, THBS2, and LOX) majorly found to play a role in gene expression regulation, dysregulated immune system, epithelial-to-mesenchymal transition, and extracellular matrix remodeling thus promoting the development of cancer and increasing the chances of recurrence after surgery and chemotherapy. …”
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Insights on the characteristics and therapeutic potential of mesenchymal stem cell-derived exosomes for mitigation of Alzheimer’s disease’s pathogenicity: a systematic review by Mohammed Yousuf Abdi, Sarah, Mustaffa Al-Bakri, Siti Sarah, Nordin, Norshariza

“…Our review discovered that most MSC exosomes could degrade Aβ plaques, enhance neurogenesis, extenuate neuroinflammatory response through microglial activation, regulate apoptosis and reduce oxidative stress. Delivery of exosomal micro-RNAs was also found to reduce neuroinflammation. …”

Expression of recombinant geobacillus SP a-amylase in pichia pastoris GS 115 by Gandhi, Sivasangkary

“…Previously, production of α-amylase SR74 in Escherichia coli expression system under regulation of T7 lac promoter in pET-32b significantly enhanced the amylase activity to 15.3 U/ml as compared to the native strain. …”
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Anti-ageing properties of edible bird's nest ascertained by in vitro and in vivo studies in animal model by Hou, Zhiping

“…Additionally, EBN produced better transcriptional regulation of hippocampal anti-oxidant genes and an Alzheimer disease isrelated genes, and hepatic insulin signaling genes. …”
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Adversarial robustness of deep reinforcement learning by Qu, Xinghua

“…Motivated by this finding, we propose a new policy distillation loss with two terms: 1) a prescription gap maximization loss aiming at simultaneously maximizing the likelihood of the action selected by the teacher policy and the entropy over the remaining actions; 2) a corresponding Jacobian regularization loss that minimizes the magnitude of gradient with respect to the input state. …”
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Time frequency analysis of functional MR images by Arun Kumar

“…Additionally, we apply the random field principle to efficiently regularize the AR(1) parameters in model-based prewhitening methods. …”
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Surface peptide functionalization of zeolitic imidazolate framework-8 for autonomous homing and enhanced delivery of chemotherapeutic agent to lung tumor cells by Nurul Akmarina, Mohd Abdul Kamal, Emilia, Abdulmalek, Sharida, Fakurazi, Cordova, Kyle E., Mohd Basyaruddin, Abdul Rahman

“…To mitigate the toxicity effect resulting from this, there is an urgent need to develop active nano delivery systems capable of regulating optimal doses specifically to cancer cells without harming adjacent normal cells. …”
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The opioid receptor influences circadian rhythms in human keratinocytes through the β-arrestin pathway by Bigliardi, Paul, Junnarkar, Seetanshu, Markale, Chinmay, Lo, Sydney, Bigliardi, Elena, Kalyuzhny, Alex, Ong, Sheena, Dunn, Ray, Wahli, Walter, Bigliardi-Qi, Mei

“…Furthermore, we observed that β-arrestin-1 regulates the transcription of its target genes, including PER2, by facilitating histone-4 acetylation. …”
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Early and strong leptin reduction is predictive for long-term weight loss during high-protein, low-glycaemic meal replacement: a subanalysis of the randomised-controlled ACOORH tri... by Kempf, Kerstin, Röhling, Martin, Banzer, Winfried, Braumann, Klaus-Michael, Halle, Martin, Schaller, Nina, McCarthy, H. David, Predel, Hans Georg, Schenkenberger, Isabelle, Tan, Susanne, Toplak, Hermann, Martin, Stephan, Berg, Aloys

“…Since leptin is involved in weight regulation, we hypothesised that a meal replacement-based lifestyle intervention would reduce leptin levels more effectively than lifestyle intervention alone. …”
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Impact of polyethylene microplastics exposure on kallikrein-3 levels, steroidal-thyroidal hormones, and antioxidant status in murine model: protective potentials of naringin by Kehinde, Samuel Abiodun, Fatokun, Tolulope Peter, Olajide, Abosede Temitope, Praveena, Sarva Mangala, Sokan-Adeaga, Adewale Allen, Adekunle, Adegbola Philip, Fouad, Dalia, Papadakis, Marios

“…PE-MPs exposure also disrupted significantly (p < 0.005) antioxidant profile by down-regulating the activities of glutathione-S-transferase, catalase (CAT), superoxide dismutase (SOD) and reducing levels of glutathione (GSH) and ascorbic acid (AA) while concentration of malondialdehyde (MDA) levels were increased relative to control. …”
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A Listeria monocytogenes aptasensor on laser inscribed graphene for food safety monitoring in hydroponic water by Cavallaro, Nicholas, Moreira, Geisianny, Vanegas, Diana, Xiang, Dong, Datta, Shoumen P. A., Gomes, Carmen, McLamore, Eric S.

“…Rapid screening of pathogens is a global need to meet food safety and water quality regulations. This study shows the importance of sensors targeting more than one bacterial surface structure in complex samples relevant to the food-water nexus.…”
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Exceptionally active iridium evolved from a pseudo-cubic perovskite for oxygen evolution in acid by Chen, Yubo, Li, Haiyan, Wang, Jingxian, Du, Yonghua, Xi, Shibo, Sun, Yuanmiao, Sherburne, Matthew, Ager, Joel W., Fisher, Adrian C., Xu, Jason Zhichuan

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High velocity domain wall propagation using voltage controlled magnetic anisotropy by Tan, Fu Nan, Gan, Wei Liang, Ang, Calvin Ching Ian, Liu, H. X., Poh, F., Lew, Wen Siang, Wong, G. D. H.

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Multiple hollow-core anti-resonant fiber as a supermodal fiber interferometer by Huang, Xiaosheng, Zang, Jichao, Yoo, Seongwoo

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Eurotium cristatum fermented okara as a potential food ingredient to combat diabetes by Chan, Li Yan, Takahashi, Masaki, Lim, Jean Pei, Aoyama, Shinya, Makino, Saneyuki, Ferdinandus, Ferdinandus, Ng, Clara Shi Ya, Arai, Satoshi, Fujita, Hideaki, Tan, Hong Chang, Shibata, Shigenobu, Lee, Ken Chi-Lik

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High yield synthesis of graphene quantum dots from biomass waste as a highly selective probe for Fe3+ sensing by Abbas, Aumber, Tabish, Tanveer A., Bull, Steve J., Lim, Tuti Mariana, Phan, Anh N.

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Dynamic properties of high-Tc superconducting nano-junctions made with a focused helium ion beam by Couëdo, François, Amari, Paul, Feuillet-Palma, Cheryl, Ulysse, Christian, Srivastava, Yogesh Kumar, Singh, Ranjan, Bergeal, Nicolas, Lesueur, Jérôme

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Graph embeddings on gene ontology annotations for protein-protein interaction prediction by Zhong, Xiaoshi, Rajapakse, Jagath Chandana

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