A critique of the use of species and below-species taxonomic terms for viruses—time for change? by Simmonds, P

“…The International Committee for the Taxonomy of Viruses (ICTV) regulates assignment and names of virus species and higher taxa through its taxonomy proposal and ratification process. …”

Multidimensional profiling of the Toxoplasma gondii proteome by Herneisen, Alice Lydia

“…The apicomplexan-specific kinase SPARK regulates the AGC kinases PKG, PKA C1, and PKA C3, which together control transitions within the asexual cycle of this important family of parasites.…”
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Mapping the structural and dynamical features of multiple p53 DNA binding domains : insights into loop 1 intrinsic dynamics by Lukman, Suryani., Lane, David P., Verma, Chandra S.

“…The transcription factor p53 regulates cellular integrity in response to stress. p53 is mutated in more than half of cancerous cells, with a majority of the mutations localized to the DNA binding domain (DBD). …”
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Biomineralization in barnacle base plate in association with adhesive cement protein by Hur, Sunyoung, Méthivier, Christophe, Wilson, Axel, Salmain, Michèle, Boujday, Souhir, Miserez, Ali

“…The protein MrCP20 present within the calcareous base plate of the acorn barnacle Megabalanus rosa (M. rosa) was investigated for its role in regulating biomineralization and growth of the barnacle base plate, as well as the influence of the mineral on the protein structure and corresponding functional role. …”
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An Efficient EAP-Based Pre-Authentication for Inter-WRAN Handover in TV White Space by Wang, Cong, Ma, Maode, Zhang, Lei

“…The IEEE 802.22 standard regulates wireless regional area network (WRAN) operating at the very high frequency and ultrahigh frequency television white space (TVWS) bands. …”
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Understanding the role of transporters and ion channels in lysosomal homeostasis by Salphati, S

“…Cellular activity is regulated based on a range of cues to maintain homeostasis. …”

Optimizing crystal size distribution based on different cooling strategies in batch crystallization process by Siti Zubaidah, Adnan, Noor Asma Fazli, Abdul Samad

“…Producing specified CSD in the crystallization process represents a main challenge as it depends on temperature control, which indirectly regulates the solution’s concentration and affects the crystal’s evolution. …”
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Sustained exposure to Helicobacter pylori induces immune tolerance by desensitizing TLR6 by Zhang, Xiulin, He, Yang, Zhang, Xiaolu, Fu, Bo, Song, Zidai, Wang, Liang, Fu, Rui, Lu, Xuancheng, Xing, Jin, Lv, Jianyi, Guo, Meng, Huo, Xueyun, Liu, Xin, Lu, Jing, Du, Xiaoyan

“…Mechanistically, we found that persistent infection with H. pylori reduces the sensitivity of TLR6 to bacterial components and regulates the expression of inflammatory cytokines in GES-1 cells through TLR6/JNK signaling. …”
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Development of quorum-sensing circuits for metabolic flux control in Escherichia coli by Dinh, Christina V.

“…Application of these regulation schemes resulted in significant production improvements in both pathways. …”
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An isolated bipolar DC-DC converter for energy storage integration in marine vessels by Nag, Soumya Shubhra, Satpathi, Kuntal, Ukil, Abhisek, Pou, Josep, Zagrodnik, Michael Adam

“…A closed loop control system is developed in the MATLAB®/Simulink simulation platform which regulates the output of the isolated bipolar converter to its reference value. …”
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Metacognitive learning in a fully complex-valued radial basis function neural network by Suresh, Sundaram, Sundararajan, Narasimhan, Savitha, R.

“…Recent studies on human learning reveal that self-regulated learning in a metacognitive framework is the best strategy for efficient learning. …”
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Elucidation of the ion transport mechanisms in CorA, a divalent cation transporter. by Nurhuda Nordin.

“…However, the mechanism of its function - how it selects and regulates its substrates, has remained unknown. Earlier, the existence of two subgroups of CorA, subgroups A and B, based on sequence homology was reported. …”
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An RRM–ZnF RNA recognition module targets RBM10 to exonic sequences to promote exon exclusion by Collins, Katherine M., Kainov, Yaroslav A., Christodolou, Evangelos, Ray, Debashish, Morris, Quaid, Hughes, Timothy, Taylor, Ian A., Makeyev, Eugene V., Ramos, Andres

“…Importantly, a second RRM domain (RRM2) of RBM10 recognizes a C-rich sequence, which explains its known interaction with the intronic 3΄ site of NUMB exon 9 contributing to regulation of the Notch pathway in cancer. Together, these findings explain RBM10's broad RNA specificity and suggest that RBM10 functions as a splicing regulator using two RNA-binding units with different specificities to promote exon skipping.…”
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Structure and inhibition of novel cyclin-dependent kinases by Dixon-Clarke, S

“…<p>Protein phosphorylation by members of the cyclin-dependent kinase (CDK) family determines the cell cycle and regulates gene transcription. CDK12 and CDK16 are relatively poorly characterised family members containing atypical domain extensions and represent novel targets for structural studies, as well as cancer drug discovery. …”

Role of posttranslational modifications of histone proteins in epigenetics by Raj, R

“…<p>Nature has evolved an additional level of genetic regulation by-passing direct changes in genetic code through the means of posttranslational modifications (PTMs) of nucleobases and histone proteins. …”

Unsupervised bayesian generative methods by Li, Shaohua

“…The third task is about Word Embedding, a technique that maps words in a natural language to continuous vectors which encode the semantic/syntactic regularities among the words. Most existing word embedding methods can be categorized into Neural Embedding Models and Matrix Factorization (MF)-based methods. …”
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BswR controls bacterial motility and biofilm formation in Pseudomonas aeruginosa through modulation of the small RNA RsmZ by Wang, Chao, Ye, Fuzhou, Kumar, Veerendra, Gao, Yong-Gui, Zhang, Lian-Hui

“…Pseudomonas aeruginosa relies on cell motility and ability to form biofilms to establish infections; however, the mechanism of regulation remains obscure. Here we report that BswR, a xenobiotic response element-type transcriptional regulator, plays a critical role in regulation of bacterial motility and biofilm formation in P. aeruginosa. …”
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Cryo-EM reveals transition states of the Acinetobacter baumannii F1-ATPase rotary subunits γ and ε, unveiling novel compound targets by Le, Khoa Cong Minh, Wong, Chui Fann, Müller, Volker, Grüber, Gerhard

“…While synthesizing ATP, it regulates ATP cleavage by its inhibitory ε subunit to prevent wasteful ATP consumption. …”
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Antifungal drug itraconazole targets VDAC1 to modulate the AMPK/mTOR signaling axis in endothelial cells by Head, Sarah A., Shi, Wei, Zhao, Liang, Gorshkov, Kirill, Pasunooti, Kalyan, Chen, Yue, Deng, Zhiyou, Li, Ruo-jing, Shim, Joong Sup, Tan, Wenzhi, Hartung, Thomas, Zhang, Jin, Zhao, Yingming, Colombini, Marco, Liu, Jun O.

“…Previous mechanistic studies have shown that itraconazole inhibits the mechanistic target of rapamycin (mTOR) signaling pathway, which is known to be a critical regulator of endothelial cell function and angiogenesis. …”
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Potential ago2/miR-3068-5p cascades in the nucleus accumbens contribute to methamphetamine-induced locomotor sensitization of mice by Liu, Dan, Liang, Min, Zhu, Li, Zhou, Ting-Ting, Wang, Yu, Wang, Rui, Wu, Fei-Fei, Goh, Eyleen Lay Keow, Chen, Teng

“…Here, we determined whether Ago2 in the NAc regulates METH sensitization in mice and identified Ago2-dependent miRNAs involved in this process. …”
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