Understanding the role of transporters and ion channels in lysosomal homeostasis by Salphati, S

“…Moreover, the protocols described here will enable to engineer sybodies against additional lysosomal targets to investigate their role in lysosomal homeostasis.…”

The role of tumour necrosis factor alpha stimulated gene-6 on bone by Afrough, S

Carbon nanotube fence-wall for radio frequency isolation by Tan, Dunlin

“…Variants of the carbon nanotube fence-wall such as channelized fence and cavity were tested, to demonstrate different ways in which it may be implemented into electronic packages for electromagnetic shielding. …”
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Characterizing the function of the Arl15 gene and its role in the development of metabolic traits by Bai, Y

“…The in vitro studies show a role for Arl15 in adipose tissue development.</p>…”

Use of static overpressure to assess the role of acoustic cavitation in ultrasound-mediated gene transfection by Ng, CK, Raymond, JL, Driscoll, C, Oldroyd, S, Huang, WE, Thompson, IP, Roy, RA

A regulatory role for repeated decoy transcription factor binding sites in target gene expression by Lee, Tek‐Hyung, Maheshri, Narendra

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BRCA1 regulation of breast cancer cell motility by Hernandez Nuñez, ZE

“…These models were used in conjunction with the siRNA knockdown of candidate proteins from the <em>in-silico</em> analysis. siRNA knockdown of SART3 significantly enhanced motility in cells lacking BRCA’s ubiquitin ligase activity, highlighting its potential role in promoting cell motility and emphasising the regulatory role of BRCA1’s ubiquitin ligase activity in breast cancer progression.…”

Role of Interferon-stimulated gene 15 (ISG15) in replication fork progression and PARP inhibitor resistance in cancer by Seung, Y

“…Understanding PARP (Poly-ADP ribose polymerase) inhibitor resistance is crucial in cancer therapy, particularly in treating cancers associated with BRCA mutations. The role of ISG15 (Interferon-Stimulated Gene 15) in PARP inhibitor resistance adds a layer of complexity to this phenomenon. …”

Proof of Travel for Trust-Based Data Validation in V2I Communication by Suo, Dajiang, Mo, Baichuan, Zhao, Jinhua, Sarma, Sanjay E.

“…While building a chain of proofs of spatial movement creates burdens for malicious vehicles, acquiring proofs does not result in extra costs for normal vehicles, which naturally want to move from the origin to the destination. …”
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Characterization and gene expression analysis of the cir multi-gene family of plasmodium chabaudi chabaudi (AS) by Lawton, Jennifer, Brugat, Thibaut, Yan, Yam Xue, Reid, Adam James, Böhme, Ulrike, Otto, Thomas Dan, Pain, Arnab, Jackson, Andrew, Berriman, Matthew, Cunningham, Deirdre, Preiser, Peter Rainer, Langhorne, Jean

“…In order to fully understand the role(s) of CIR proteins during P. chabaudi infection, a detailed characterization of the cir gene family was required. …”
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Gene and sample selection for cancer identification by Mundra Piyushkumar Arjunlal

“…Gene-expression data gathered with microarrays play an important role in detection, classification, and understanding of many diseases including cancer. …”
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CRISPR-Cas9-mediated gene editing of MYB28 genes impair glucoraphanin accumulation of Brassica oleracea in the field by Neequaye, M, Stavnstrup, S, Harwood, W, Lawrenson, T, Hundleby, P, Irwin, J, Troncoso-Rey, P, Saha, S, Traka, MH, Mithen, R, Ostergaard, L

“…In this study, we sought to study the role of MYB28 in the regulation of aliphatic glucosinolate (A-GSL) biosynthesis and associated sulfur metabolism in field-grown Brassica oleracea with the use of Clustered Regularly Interspaced Short Palindromic Repeats (CRISPR)-Cas9 gene-editing technology. …”

Unravelling gene regulation in the epidermis during differentiation by Anisa Banu Abdul Rahim

“…This study has paved ways to understand the critical role of polyamines in the epidermis and the complexity of the gene regulatory network that drives keratinocyte differentiation.…”
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Hox gene expression in early zebrafish embryo by Stephanie

“…However, there are also reports on Hox genes such as hoxd4a acting at pre-gastrulation or peri-gastrulation, implicating their roles in other processes such as haematopoiesis or neural patterning. …”
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In vitro and in silico investigation of TRPC3 mechanism and dynamics by Collingridge, J

“…This has not previously been reported for TRPC3, and simulations presented here suggest a role for the π-helix in promoting a transition towards an open state of the channel. …”

Whole genome analysis of Hawksbill turtles in Singapore reveals their genetic adaptations to disease and sensory perception by Desai, Archita Sanjay

“…Based on the results of this study, 94 genes located across the whole genome likely underwent positive selection. …”
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Gene expression regulation by well-known non-coding RNAs by Tan, Jiazi

“…From there, we could screen for genes important for XCI by rescuing the differentiated transgenic ES cells by gene silencing. …”
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Investigation of NOT1 proteins in regulating gene expression in plasmodium falciparum by Liu, Ying

“…The independent mutation of Not1.1 and Not1.2 leads to altered mRNA abundance of many genes, including many egress- and invasion-related genes, which may result in defective growth and invasion rate. …”
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Nanopore sequencing analysis of integron gene cassettes in sewages and soils by An, Xin-Li, Abass, Olusegun K., Zhao, Cai-Xia, Xu, Mei-Rong, Pan, Ting, Pu, Qiang, Liao, Hu, Li, Hu, Zhu, Yong-Guan, Su, Jian-Qiang

“…This study underlined that soil and sewage were potential reservoirs for integron-mediated ARGs transfer, indicating that anthropogenic activity played a vital role in the prevalence and diversity of resistance gene cassettes in integrons.…”
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Genotype-phenotype maps for gene networks: from evolution to computation by Camargo, FQ

“…</p> <p>Next, we investigate multiple models of GP maps for gene regulatory networks (GRNs). These include Boolean threshold networks, where we fix the strength of gene interactions, while varying the network topology, as well as systems of differential equations, where we fix the network topology while varying interaction strengths. …”