Gene expression regulation by well-known non-coding RNAs by Tan, Jiazi

“…From there, we could screen for genes important for XCI by rescuing the differentiated transgenic ES cells by gene silencing. …”
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Manufacturing mesenchymal stromal cells in a microcarrier-microbioreactor platform can enhance cell yield and quality attributes: case study for acute respiratory distress syndrome by Krupczak, Brandon, Farruggio, Camille, Van Vliet, Krystyn J.

“…Next, we identified 24 genes implicated in a therapeutic role for a specific motivating indication, acute respiratory distress syndrome (ARDS); expression of these genes served as our pCQAs for initial in vitro evaluation of product potency. …”
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Effect of detergent, herbs and spices on the growth of Vibrio parahaemolyticus biofilm in seafood by Nillian, Elexson

“…The prevalence of 9.14% (36/394) of positive toxR genes, 63.8% of positive isolates contained virulent genes of V. parahaemolyticus tdh+, 22.2% of V. parahaemolyticus trh+, and 5.56% (2/36) of positive isolates in both V. parahaemolyticus tdh+ and trh+ had been detected. …”
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A rapid CRISPR competitive assay for in vitro and in vivo discovery of potential drug targets affecting the hematopoietic system by Shen, Yunbing, Jiang, Long, Iyer, Vaishnavi Srinivasan, Raposo, Bruno, Dubnovitsky, Anatoly, Boddul, Sanjaykumar V., Kasza, Zsolt, Wermeling, Fredrik

“…CRISPR/Cas9 can be used as an experimental tool to inactivate genes in cells. However, a CRISPR-targeted cell population will not show a uniform genotype of the targeted gene. …”
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Antidiabetic activity of Curculigo latifolia extracts in vitro and in vivo studies by Ishak, Nur Akmal

“…The regulatory effects of C. latifolia fruit:root extracts on genes involved in glucose and lipid metabolisms were further studied. …”
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Validating predictive sequence analysis in polyketide stereochemical determination though the synthesis of stambomycin D by Lim, J

“…<p>In recent years, predictive gene sequence analysis of biosynthetic enzymes has emerged as a powerful tool for the stereochemical determination of natural products. …”

Detection and characterisation of a sixth Candida auris clade in Singapore: a genomic and phenotypic study by Suphavilai, Chayaporn, Ko, Karrie Kwan Ki, Lim, Kar Mun, Tan, Mei Gie, Boonsimma, Patipan, Chu, Joash Jun Keat, Goh, Sui Sin, Rajandran, Prevena, Lee, Lai Chee, Tan, Kwee Yuen, Bushra Binte Shaik Ismail, Aung, May Kyawt, Yang, Yong, Sim, Jean Xiang Ying, Venkatachalam, Indumathi, Cherng, Benjamin Pei Zhi, Spruijtenburg, Bram, Chan, Kian Sing, Oon, Lynette Lin Ean, Tan, Ai Ling, Tan, Yen Ee, Wijaya, Limin, Tan, Ban Hock, Ling, Moi Lin, Koh, Tse Hsien, Meis, Jacques F., Tsui, Clement Kin Ming, Nagarajan, Niranjan

“…Antifungal susceptibility testing was done and antifungal resistance genes, mating-type locus, and chromosomal rearrangements were characterised from the WGS data of the three investigated isolates. …”
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Morphological multiparameter filtration and persistent homology in mitochondrial image analysis by Chung, Yu-Min, Hu, Chuan-Shen, Sun, Emily, Tseng, Henry C.

“…Using this information, we also develop a connectivity index that describes the morphology of the branching patterns. As proof of concept, we utilize this approach to study how mitochondrial networks are altered by genetic changes in the Optineurin gene. …”
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Detection of single-nucleotide polymorphisms in Plasmodium falciparum by PCR primer extension and lateral flow immunoassay by Moers, APHA, Hallett, R, Burrow, R, Schallig, HDFH, Sutherland, CJ, van Amerongen, A

“…Primer extension methods (PEXT) were developed to identify 4 SNPs in P. falciparum positioned at amino acids 86, 184, and 1246 of the P. falciparum multidrug resistance 1 gene (pfmdr1) and amino acid 76 of the chloroquine resistance transporter gene (pfcrt). …”

Alleviation of off-target effects from vector-encoded shRNAs via codelivered RNA decoys by Mockenhaupt, Stefan, Grosse, Stefanie, Rupp, Daniel, Bartenschlager, Ralf, Grimm, Dirk

“…Our combination of shRNA and TuD in a single bicistronic gene transfer vector derived from Adeno-associated virus (AAV) enables a wide range of applications, including gene therapies. …”
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Scaffold-mediated sustained, non-viral delivery of miR-219/miR-338 promotes CNS remyelination by Milbreta, Ulla, Lin, Junquan, Pinese, Coline, Ong, William, Chin, Jiah Shin, Shirahama, Hitomi, Mi, Ruifa, Williams, Anna, Bechler, Marie E., Wang, Jun, ffrench-Constant, Charles, Hoke, Ahmet, Chew, Sing Yian

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Injectable cell transplantation system for cytokine-based cancer immunotherapy by Gerard Nathanael Adrianus.

“…These results confirmed the proofs-of-principle and feasibility of the proposed system.…”
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