Preparation for and performance of a Pseudomonas aeruginosa biofilm experiment on board the International Space Station by Flores, Pamela, Schauer, Rylee, McBride, Samantha A., Luo, Jiaqi, Hoehn, Carla, Doraisingam, Shankini, Widhalm, Dean, Chadha, Jasmin, Selman, Leah, Mueller, Daniel Wyn, Floyd, Shannon, Rupert, Mark, Gorti, Sridahr, Reagan, Shawn, Varanasi, Kripa K., Koch, Christina, Meir, Jessica U., Muecklich, Frank, Moeller, Ralf, Stodieck, Louis, Countryman, Stefanie, Zea, Luis

“…Additionally, we describe the performance of the experiment on board the ISS, including crew activities, use of assets, temperature profile, and experiment timeline; all leading to a successful spaceflight experiment. …”
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CRISPR locus sequencing for Mycobacterium detection and differentiation by Zhen, Yashu

“…Mycobacterium tuberculosis Complex (MTBC) refers to a group of Mycobacterium species that sharing same ancestor and all can cause tuberculosis. As each MTBC specie also has lots of different strains, which related to drug-resistance and outbreak prevention, it is important to keep detecting and differentiating them clearly. …”
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Impact of pyridyl moieties on the inhibitory properties of prominent acyclic metal chelators against metallo-β-lactamase-producing Enterobacteriaceae : investigating the molecular... by Sosibo, Sphelele C., Somboro, Anou M., Amoako, Daniel G., Osei Sekyere, John, Bester, Linda A., Ngila, Jane C., Sun, Darren Delai, Kumalo, Hezekiel M.

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In silico screening of sugar alcohol compounds to inhibit viral matrix protein VP40 of Ebola virus by Nagarajan, Nagasundaram, Yapp, Edward Kien Yee, Le, Nguyen Quoc Khanh, Yeh, Hui-Yuan

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Improving access to pulmonary rehabilitation for patients with COPD treated for substance misuse in the London Borough of Islington by Narasimhan, Divya, Simpson, Jane, Stewart, Duncan

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Barriers and leverage points for seeing alcohol differently in integrated care systems in England: a senior stakeholder interview study by Madden, Mary, Stewart, Duncan, McCambridge, Jim

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Investigation of phenylpropanoid sucrose esters as antidiabetic compounds by Wong, Kathy Pooi Wen

“…Alpha glucosidase inhibitors (AGIs) are a class of anti-diabetic drug known for their effectiveness and safety. However, they are associated with gastrointestinal (GI) side-effects such as diarrhoea, nausea and flatulence. …”
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The treatment of malaria in pregnancy by Nosten, F, McGready, R

“…Studies are urgently needed to define the best therapeutic options and to develop new treatments, especially in Africa where drug resistance already compromises all strategies of control.…”

Blood brain barrier: a tissue engineered microfluidic chip by Musafargani, Sikkandhar, Mishra, Sachin, Gulyás, Miklós, Mahalakshmi, P., Archunan, Govindaraju, Padmanabhan, Parasuraman, Gulyás, Balázs

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An analysis of heavy silicone oil treatment for inferior proliferative vitreoretinopathy by Hammer, M, Ie, A, Eibenberger, K, Auffarth, GU, Xue, K

“…The number of glaucoma drugs were increased in 45% of patients during Densiron tamponade. …”

Investigation of Synthetic Proteins Produced via Automated Fast-Flow Peptide Synthesis by Cowfer, Amanda Elizabeth

“…I will discuss the iterative steps my team took to vary both chemical and mechanical and control variables to improve per-coupling yield enough to enable access to full-length single-domain proteins. On this journey, we utilized test peptides to validate synthesis quality and later synthesized a suite of full-length single-domain biologically active proteins. …”
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nCVTs : a hybrid smart tumour targeting platform by Goh, Wei Jiang, Zou, Shui, Czarny, Bertrand, Pastorin, Giorgia

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Design and in vitro release study of siRNA loaded Layer by Layer nanoparticles with sustained gene silencing effect by Tan, Yang Fei, Lee, Ying Shi, Seet, Li-Fong, Ng, Kee Woei, Wong, Tina T., Venkatraman, Subbu

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Layer-by-layer polyelectrolyte coated erythrocyte carriers by Heng, Puay Ling.

“…This report shows the need to improve the process due to the increased interest in using carrier erythrocytes as drug delivery system. The erythrocytes coated with a polyelectrolyte multilayer provide a simple mean for controlling the burst and subsequent release of bioactive agents. …”
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Computational analysis for infectious diseases surveillance and host-pathogen interactions (in the context of Influenza A viruses) by Beyene, Biruhalem Taye

“…Hence, development of a broad range anti-IAV drug that could target all of the IAV strains irrespective of their source is critically important. …”
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Anti-leukaemic and chemotherapy supportive effects of berberis vulgaris l. Fruit crude extract on in vitro and in vivo models by Saedi, Tayebeh Azam

“…All data were analyzed using one-way ANOVA followed by Duncan's multiple post hoc tests. …”
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Linking dual mode of action of host defense antimicrobial peptide thanatin: structures, lipopolysaccharide and LptAm binding of designed analogs by Sinha, Sheetal, Dhanabal, Vidhya Bharathi, Sperandeo, Paola, Polissi, Alessandra, Bhattacharjya, Surajit

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Antimicrobial photodynamic therapy for the remote eradication of bacteria by Yan, Evelias, Kwek, Germain, Ng, Shuang Qing, Lingesh, Shonya, Xing, Bengang

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Utilizing food waste and thermoplastic starch (TPS) in 3D printed PLA formulations for sustainable and customizable controlled delivery systems by Wang, Liwen

“…With the addition of TPS, the drug release profile can be adjusted from 8 – 120 hours using different TPS ratios and different printed wall thicknesses. …”
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Translation termination mechanism studied by solution state NMR by Li, Yan

“…In eukaryotes, class-I release factor (eRF1) directly recognizes all three stop-codons in the A site on the small ribosomal subunit and stimulates peptide release. …”
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