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Multiscale topological indices for the quantitative prediction of SARS CoV-2 binding affinity change upon mutations
Published 2023“…Biologically, protein-protein interactions between SARS-CoV-2 surface spike (S) protein and human ACE2 protein are the key mechanism behind the COVID-19 disease. …”
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Characterising the T cell responses to SARS-CoV-2 including variants of concern induced by natural infection and vaccines
Published 2024“…<p>The COVID-19 pandemic, caused by SARS-CoV-2, has profoundly impacted global health, prompting extensive research into vaccine responses and the immune dynamics of SARS-CoV2 variants of concern (VOCs). …”
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Detecting changes in population trends in infection surveillance using community SARS-CoV-2 prevalence as an exemplar
Published 2024“…Substantial changes in SARS-CoV-2 prevalence with emergence of variants provides opportunity to investigate different methods to do this. …”
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A systems biology approach to define SARS-CoV-2 correlates of protection in non-human primates
Published 2024“…SARS-CoV-2 is expected to become a seasonal human coronavirus, with annual vaccination advised for vulnerable populations, similar to influenza. …”
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Chronic neuropsychiatric sequelae of SARS-CoV-2: protocol and methods from the Alzheimer's Association Global Consortium
Published 2022“…No available evidence supports the notion that cognitive impairment after SARS-CoV-2 infection is a form of dementia (ADRD or otherwise). …”
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Flood inundation mapping in the Kelantan River Basin, Malaysia, using Sentinel-1 SAR and Google Earth Engine
Published 2024“…In this study, GEE was utilized to generate flood inundation maps for the Kelantan River Basin (KRB) using Sentinel-1 SAR data. Site inspections and Sentinel-2 Multispectral Instrument (MSI) satellite images of the actual flood regions were then used to validate the flood inundation maps. …”
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Imprinting of IgA responses in previously infected individuals receiving bivalent mRNA vaccines (WT and BA.4/BA.5 or WT and BA.1)
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Using computer networks, internet and email as productivity tools for education
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Factors affecting duration of SARS-Cov-2 viral shedding in mildly symptomatic patients isolated in a community facility
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SARS-CoV-2 human challenge reveals biomarkers that discriminate early and late phases of respiratory viral infections
Published 2024“…We use high frequency sampling in the SARS-CoV-2 human challenge model to show induction of IFN-stimulated gene (ISG) expression with different temporal and cellular profiles. …”
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Halal beauty supply chain and sustainable operational excellence: A moderator of the post-SARS-CoV-2 mitigation strategy
Published 2024“…The second objective is to investigate Post-SARS-CoV-2 mitigation strategies executed by halal beauty companies in Malaysia. …”
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Enhanced cholesterol-dependent hemifusion by internal fusion peptide 1 of SARS Coronavirus-2 compared to its N-terminal counterpart
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A 98.6 dB SNDR SAR ADC with a mismatch error shaping technique implemented with double sampling
Published 2022“…A novel mismatch error shaping (MES) method is proposed in noise-shaping (NS) SAR ADCs to break the SNDR limitation caused by DAC mismatch induced non-linearity. …”
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High-density lipoprotein function is modulated by the SARS-CoV-2 spike protein in a lipid-type dependent manner
Published 2023“…There is a close relationship between the SARS-CoV-2 virus and lipoproteins, in particular high-density lipoprotein (HDL). …”
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Dok3 restrains neutrophil production of calprotectin during TLR4 sensing of SARS-CoV-2 spike protein
Published 2023“…However, the precise mechanism controlling calprotectin production during SARS-CoV-2 infection remains elusive. In this study, we showed that Dok3 adaptor restrains calprotectin production by neutrophils in response to SARS-CoV-2 spike (S) protein engagement of TLR4. …”
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The SARS-CoV-2 nucleocapsid protein interferes with the full enzymatic activation of UPF1 and its interaction with UPF2
Published 2025“…These results unveil a novel, multi-faceted mechanism by which SARS-CoV-2 evades the host’s defenses and manipulates cellular components. …”
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Back to the Basics of SARS-CoV-2 Biochemistry: Microvascular Occlusive Glycan Bindings Govern Its Morbidities and Inform Therapeutic Responses
Published 2024“…Notably, the two human betacoronaviruses that express a sialic acid-cleaving enzyme are benign, while the other three—SARS, SARS-CoV-2 and MERS—are virulent. RBC aggregation experimentally induced in several animal species using an injected polysaccharide caused most of the same morbidities of severe COVID-19. …”
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