Outlier detection by Li, Shukai

“…Amongst them, unsupervised outlier detection has been the most popular, while relative outlier detection has attracted increasing attention in recent years. Thus, our research will focus on these two classes of outlier detection problems. …”
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Mm-wave CMOS phase-locked loops by Yi, Xiang

“…The challenges of mm-wave phase-locked loop (PLL) design are high frequency, wide locking range, low phase noise, and low power. In recent years, many reported mm-wave PLLs in CMOS technology still face the problem of poor phase noise due to the low quality factor (low-Q) passive devices and noisy MOS transistors. …”
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Development and application of novel proteomics methods in proteomics research by Hao, Piliang

“…The sensitivity, throughput and accuracy of proteomics have improved considerably in the past years due to the development of novel technologies. …”
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Peroxytungstate anions in asymmetric ion pair catalyzed oxidations by Ye, Xinyi

“…The following two chapters presented two projects utilizing the designed strategy. Over the last few years, our group has developed a series of phase-transfer catalysts, which successfully solved problems in the enantioselective addition and substitution reaction under traditional base promoted conditions. …”
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A preliminary investigation into the use of cannabis suppositories and online mindful compassion for improving sexual function among women following gynaecological cancer treatment by Banbury, Sam, Tharmalingam, Hannah, Lusher, Joanne, Erridge, Simon, Chandler, Chris

“…Eighty-three participants aged between 18 and 50+ years who were at least six months post-cancer treatment were randomly allocated to one of four groups, depending on whether they were already using cannabis suppositories. …”
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Precursors and correlates of transient and persistent longitudinal profiles of psychotic experiences from late childhood through early adulthood by Rammos, A, Sullivan, SA, Kounali, D, Jones, HJ, Hammerton, G, Hines, LA, Lewis, G, Jones, PB, Cannon, M, Thompson, A, Wolke, D, Heron, J, Zammit, S

“…</p> <br> <p><strong>Method:</strong> Using data from 8045 individuals from a birth cohort study, longitudinal profiles of psychotic experiences based on semi-structured interviews conducted at 12, 18 and 24 years were defined. Environmental, cognitive, psychopathological and genetic determinants of these profiles were investigated, along with concurrent changes in psychopathology and cognition.…”

West African labour and the development of mechanised mining in southwest Ghana, c.1870s to 1910 by Mark-Thiesen, C

“…Divided into three sections, this thesis examines the practice of indirect labour recruitment for the mines during the formative years of colonial rule; the incorporation of ‘traditional’ credit relationships into ‘modern’ commerce. …”

Markers of synovial inflammation in cohorts at risk of knee osteoarthritis by Kluzek, S

“…Data from two cohorts has been utilised for the purpose of this thesis: the Oxford Knee Injury Cohort, a prospective study of NHS patients with recent ACL and/or meniscal injuries, and the Chingford women’s study, a community-based prospective cohort with over 23 years of follow-up. </p> <p><b>Results.</b> Cross-sectionally, sonographic markers correspond well with microscopically defined post-traumatic synovitis. …”

Cohort differences in physical health and disability in the United States and Europe by Gimeno, L, Goisis, A, Dowd, JB, Ploubidis, GB

“…<p><strong> Methods</strong></p> Using data from nationally representative studies of adults aged ≥50 years from the United States (Health and Retirement Study, n = 26,939), England (English Longitudinal Study of Ageing, n = 14,992) and 11 continental European countries (Survey of Health, Ageing and Retirement in Europe, n = 72,595), we estimated differences in the age-adjusted prevalence of self-reported chronic disease and disability and observer-measured health indicators across pseudo-birth cohorts (born &lt;1925, 1925–1935, 1936–1945, 1946–1954, 1955–1959). …”

The Pandemic EVIDENCE Collaboration Pillar 1: diagnostics and transmission by Conly, J, Plüddemann, A, Jefferson, T, Rosca, C, Heneghan, C

“…Despite the learnings from the recent pandemic, significant gaps remain in our understanding of the diagnosis of acute respiratory viral infections and their sequelae, the modes of transmission, and how to effectively synthesise the existing evidence from the past 70 years of research on respiratory viruses. It is crucial to examine further the evidence on how common respiratory viral agents are transmitted. …”

Depressive symptoms in adolescence and adult educational and employment outcomes: a structured life course analysis by López-López, JA, Tilling, K, Pearson, RM, Fazel, MS, Washbrook, E, Zhu, Y, Smith, BJ, Dunn, EC, Smith, ADAC

“…</p> <br> <p><strong>Results:</strong> Our analysis sample included participants with full information on NEET status (N = 3951), and the results supported the accumulation of risk model, showing that the odds of NEET increase by 1.015 (95% CI 1.012–1.019) for an increase of 1 unit in depression at any age between 11 and 24 years.</p> <br> <p><strong>Conclusions:</strong> Given the adverse implications of NEET status, our results emphasize the importance of supporting mental health during adolescence and early adulthood, as well as considering specific needs of young people with re-occurring depressed mood.…”

The association between the proportion of Brexiters and COVID-19 death rates in England by Phalippou, L, Wu, B

“…</p> <p><strong>Objective:</strong> Ecological study of whether there exists a significant conditional correlation between two variables that appear unrelated except for attitude towards experts: i) Proportion of people voting in favor of remaining in the European Union in 2016 and ii) COVID-19 outcomes four years later: death rates, vaccination rates. A significant conditional correlation would indicate that polarized beliefs have important consequences across a broad spectrum of societal challenges. …”

The Pandemic EVIDENCE Collaboration Pillar 2: interventions and evidence by Fretheim, A, Onakpoya, I, Bartoszko, J, Jones, M, Gandini, S

“…Pilot and feasibility studies are needed to determine how we may best develop evidence for NPIs for viral respiratory pathogens in seasonal endemic and epidemic settings and how this evidence should be optimally applied in the intervening years to reduce uncertainties during future pandemics.…”

Genetic, natal, and spatial drivers of social phenotypes in wild great tits by Satarkar, D, Sepil, I, Sheldon, BC

“…Centrality showed heritability up to 10% in one of 3&thinsp;years sampled, whereas betweenness showed none, indicating modest genetic variation in individual sociability, but not group-switching tendencies. …”

Use of intravenous immunoglobulin for the treatment of autoimmune encephalitis: audit of the NHS experience by Kinsella, JA, Irani, SR, Hollingsworth, R, O’Shaughnessy, D, Kane, P, Foster, M, Schott, JM, Lunn, MP

“…</p> <p><strong>Results</strong> A total of 625 patients who were 18 years of age or older were treated with intravenous immunoglobulin for autoimmune encephalitis, of whom 398 were determined as having 'highly likely' or 'definite' autoimmune/limbic encephalitis. …”

Diagnostic accuracy of point-of-care lung ultrasound for community-acquired pneumonia in children in ambulatory settings: a systematic review and meta-analysis by Hughes-Davies, H, Ukwatte, U, Roberts, N, Turner, PJ, Hayward, GN, Fanshawe, TR, Bird, C

“…<p><strong>Introduction:&nbsp;</strong>To perform a systematic review of the diagnostic accuracy of point-of-care lung ultrasound, compared to chest radiography, in children and young people (0&ndash;21 years) who present to ambulatory settings with suspected community-acquired pneumonia.…”

The role of circulating tumor DNA in melanomas of the uveal tract by Zameer, MZ, Jou, E, Middleton, M

“…Accordingly, although current treatments have an excellent local disease control rate, approximately 50% of patients develop metastatic relapse within 10 years. The high risk for metastatic disease with a variable and often long latency period is thought to be due to early spread of cancer cells disseminating into organs such as the liver, followed by a period of dormancy, before the eventual emergence of radiologically measurable disease. …”

Burden of diseases attributable to excess body weight in 204 countries and territories, 1990–2019 by Safiri, S, Grieger, JA, Ghaffari Jolfayi, A, Mousavi, SE, Nejadghaderi, SA, Fazlollahi, A, Sullman, MJM, Karamzad, N, Sahin, F, Singh, K, Collins, GS, Kolahi, A

“…For adults, EBW was defined as a body mass index (BMI) exceeding 25 kg/m2, while for children aged 1 to 19 years, EBW was determined according to the standards set by the International Obesity Taskforce. …”

Maternal postpartum six-week check and short-term health outcomes for women with hypertensive disorders in pregnancy: an observational study using the Clinical Practice Research Da... by Ramakrishnan, R, Korb, D, Li, Y, Knight, M, Carson, C

“…</p> <br> <p><strong>Methods:</strong> Data were from the UK Clinical Practice Research Datalink GOLD for women aged 15-49 years at childbirth in 2000–2018, who were diagnosed with HDP, and were registered for &gt;12 months postpartum. …”

Characterisation of the genomes of brain metastases by Ulahannan, D

“…Interventions include surgery and stereotactic radiosurgery with few metastases, with whole brain radiotherapy serving a role in patients with several metastases. In recent years, there have been increased efforts directed towards early phase trials to address the role of targeted biological agents towards pathogenic drivers namely, <em><b>EGFR, HER2</b></em> and <em><b>BRAF</b></em>. …”