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Introducing Philosophy Through Pop Culture : From Socrates to Star Wars and Beyond /
Published 2022“…A closer examination, however, reveals that South Park is very much within the Platonic tradition, as Kyle and Stan engage in questioning and dialogue in order to "learn something today." …”
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software, multimedia -
2
Analysis of hepatocyte antigen presentation and T cell/hepatocyte interaction in the context of hepatitis B virus Infection.
Published 2010“…Hepatitis B Virus (HBV) has evolved multiple immune escape strategies in order to establish persistent infection in the host. …”
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Final Year Project (FYP) -
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Phase transitions by an abundant protein in the anammox extracellular matrix mediate cell-to-cell aggregation and biofilm formation
Published 2021“…The Brosi_A1236 structure was computationally predicted to consist of immunoglobulin-like anti-parallel β-strands, and circular dichroism conducted on the isolated surface protein indicated that β-strands are the dominant higher-order structure. The isolated protein was stained positively by the β-sheet-specific stain thioflavin T, along with cell surface- and matrix-associated regions of the biofilm. …”
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Journal Article -
4
Techniques for analysis and integration of histology data and agent-based modelling of T cell-tumour interactions
Published 2023“…Immunotherapies are increasingly being developed to target aspects of the immune system, such as CD8+ T cells, in order to boost its anti-tumour response. In clinical trials of such therapies, patients are monitored in several ways, often including core-needle biopsies in which a small piece of the tumour is removed, stained for specific cell markers, and imaged.…”
Thesis -
5
Correlative light and electron microscopy of telomeric repeat-binding factor 1 in mammalian cells
Published 2019“…Chromatin fibers range from 5 nm to 30 nm in diameter with a mean diameter of 18.5 nm which decreases to 13.1 nm in low salt conditions. In order to establish a comparative data-set of telomeric and non-telomeric chromatin, nucleosomes were stained for CLEM by eGFP_APEX2 labelling of H2B. …”
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Thesis -
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Growth of myxococcus xanthus in continuous-flow-cell bioreactors as a method for studying development
Published 2015“…To demonstrate the versatility of our growth environment, we carried out time-lapse confocal laser scanning microscopy to visualize M. xanthus biofilm growth and fruiting body development, as well as fluorescence staining of exopolysaccharides deposited by biofilms. …”
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Journal Article -
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Multi-spectral polarimetry imaging for early gastric cancer diagnosis
Published 2016“…This dissertation presents several studies in the development of polarimetry imaging techniques for gastric cancer diagnosis in order to approach the eventual goal of the detection of early gastric cancer in vivo in real time. …”
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Thesis -
9
Construction and characterization of a Lactococcus lactis in-trans surface display system harboring murine glycosylated tyrosinase related protein-2
Published 2015“…Codon optimized mtrp-2 and cA genes also did not result in target protein production. In order to investigate post-translational modification interruption, expression of codon optimized mtrp-2125-276 epitope devoid of mtrp-2 native maturation signal peptide was performed which resulted in misfolded plus aggregated mTRP-2125-276 and mTRP-2125-276 –cA protein production. …”
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Thesis -
10
Conditional knock out of N-WASP in keratinocytes causes skin barrier defects and atopic dermatitis-like inflammation
Published 2018“…Neural-Wiskott Aldrich Syndrome Protein (N-WASP) is expressed ubiquitously and regulates actin cytoskeleton remodeling. In order to characterize the role of N-WASP in epidermal homeostasis and cutaneous biology, we generated conditional N-WASP knockout mouse using CK14-cre (cytokeratin 14) to ablate expression of N-WASP in keratinocytes. …”
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Journal Article