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Liposomal encapsulation of pro-NO donor drug
Published 2020“…Liposomes are utilised as drug carrier due to its biocompatibility and inert nature in the physiological body, to protect the drug as well as prevent premature elimination by the body. …”
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Final Year Project (FYP) -
2
Nanosized silica particles for achiral drug separation
Published 2009“…It is widely recognized that the full potential of rapid chromatography can be realized with very small support particulates and tailor-made chiral stationary phase. …”
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Research Report -
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Assignment optimization of pandemic influenza antiviral drugs in Urban pharmacies
Published 2020“…Antiviral drugs have benefited public health officers to elucidate outbreak risks by controlling influenza pandemics efficacious, especially effective in the early stage of epidemic outbreaks. …”
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Journal Article -
4
18F-labelling of new chemotypes for drug discovery
Published 2016“…Finally, Chapter 5 gives full experimental procedures and characterisation data for all compounds.…”
Thesis -
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Amplifying signals in the tumor microenvironment for drug development and diagnostics
Published 2024“…Leveraging advancements in high throughput screening and in deep learning, we contribute important tools for the effective design of conditional drugs that require the cleavage of a protease substrate to unleash drug cytotoxicity. …”
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Thesis -
6
Dynamic drug combination methods for suppressing bacterial antibiotics resistance adaptation
Published 2014“…This work opens up the research into the novel strategies but using currently available drugs and synergistic phytochemicals instead of depending on new drugs. …”
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Thesis -
7
Near-infrared light for phototherapy : photothermal induced drug release and tumor ablation
Published 2015“…Though the eventual outcome is not satisfactory, it still provided some inspirations for my follow-up research. …”
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Thesis -
8
Functional genomics reveals an off-target dependency of drug synergy in gastric cancer therapy
Published 2024“…However, realizing the full potential of this approach requires a clear comprehension of the genetic dependencies underlying drug synergy. …”
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Article -
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Controlled-release nanoencapsulating microcapsules to combat inflammatory diseases
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Journal Article -
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Evaluation of paper spray mass spectrometry for direct analysis of small molecule drugs and hemoglobin constant spring peptide markers
Published 2016“…The studies described in this thesis were undertaken to evaluate the application of paper spray mass spectrometry for direct analysis of small molecule drugs and biomarker in dried matrix spot samples. …”
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Thesis -
11
Glass box and black box machine learning approaches to exploit compositional descriptors of molecules in drug discovery and aid the medicinal chemist
Published 2024“…The synthetic medicinal chemist plays a vital role in drug discovery. Today there are AI tools to guide next syntheses, but many are “Black Boxes” (BB). …”
Journal article -
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Part I : Peptide functionalized materials for gram-negative bacteria targeted PDT and LPS sensing. Part II : Small peptide and membrane lipid based self-assembled nanostructures fo...
Published 2014“…The subsequent study using such clickable MVs as controlled drug/gene delivery vehicles is still in progress.…”
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Thesis -
14
SP.236 / ES.SP236 Exploring Pharmacology, Spring 2009
Published 2009“…From Abilify to Zyrtec, the world is full of interesting drugs. Such substances have cured diseases, started wars, and ended careers. …”
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Learning Object -
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Synthesis, antimalarial activity, and molecular dynamic approaches of salophen metal complexes
Published 2024“…Malaria is still one of the main infectious diseases in tropical climates. …”
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Article -
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Low-power processors for implantable epileptic seizure detection system
Published 2013“…Despite several treatments are available to suppress the seizure such as anti-epileptic drugs and surgery, around 25% of the epileptic patients still experiences the seizure. …”
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Final Year Project (FYP) -
17
Mitochondrial dysfunction in Down Syndrome: from pathology to therapy
Published 2023“…Mitochondrial dysfunctions have been described in Down syndrome (DS) caused by either partial or full trisomy of chromosome 21 (HSA21). Mitochondria play a crucial role in various vital functions in eukaryotic cells, especially in energy production, calcium homeostasis and programmed cell death. …”
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Effect of metabolite and temperature on artificial human sweat characteristics over a very wide frequency range (400 MHz–10.4 GHz) for wireless hydration diagnostic sensors
Published 2023“…As a result, analysis of electrolytes in this biofluid is gaining traction in the development of non-invasive sweat diagnostics to determine level of dehydration, cystic fibrosis and illicit drugs. This paper presents a wireless measurement modality of permittivity properties of sweat of different metabolite concentration levels exemplifying the full spectrum of human sweat. …”
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Cell charactetization in differnet regions of the native annulus fibrous in a porcine intervetebral disc model through cell sorting and molecular analysis
Published 2016“…However, the cell biology of the AF is still poorly understood especially the different cell types that exist within the AF. …”
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Final Year Project (FYP) -
20
Cheaper Than A Funeral: Considering Ibogaine’s Psychedelic Journey and Therapeutic Potential
Published 2024“…It is also considered the most extreme of the psychedelic drugs currently known to researchers. For the past fifty years, it’s been used to treat severe substance use disorders, particularly with highly addictive opioids and stimulants. …”
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Thesis