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1
Biotin-streptavidin binding interactions of dielectric filled silicon bulk acoustic resonators for smart label-free biochemical sensor applications
Published 2014“…Sensor performance of a dielectric filled silicon bulk acoustic resonator type label-free biosensor is verified with biotin-streptavidin binding interactions as a model system. …”
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Journal Article -
2
Biocementation of sand filled geotextile tubes
Published 2019“…Nonetheless, the strength and durability of geotextile tubes that filled with sand or clay slurry still need to be improved. …”
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Final Year Project (FYP) -
3
Structural characterization of the full-length Hantaan virus polymerase
Published 2024“…We determine a series of structures at resolutions between 2.7 and 3.3 Å of RNA free polymerase comprising the core, core and endonuclease, and a full-length polymerase. The full-length polymerase structure depicts the location of the cap binding and C-terminal domains which are arranged in a conformation that is incompatible with transcription and in a novel conformation not observed in previous conformations of cap-snatching viral polymerases. …”
Journal article -
4
Evaluation of keratin templates on dermal regeneration of full-thickness burns
Published 2024“…Full-thickness burns presents themselves as damages to both epidermis and dermis, and may affect the subcutaneous tissue, muscular, neurovascular, and skeletal structures. …”
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Thesis-Doctor of Philosophy -
5
Structural and functional characterisation of the collagen binding domain of fibronectin
Published 2007“…However, the presence of at least a single GlcNAc sugar residue on the second sugar chain site on 8Fn1 (N- linked to N511) is essential for full affinity binding to collagen. Direct binding of the 8Fn1-9Fn1 module pair to collagen is assessed with a short collagen peptide and the binding is monitored by NMR. …”
Thesis -
6
Structural basis of RNA binding by leucine zipper GCN4
Published 2013“…Further studies in the context of full-length bZIP factors are envisaged to address the biological relevance of LZ RNase activity.…”
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Journal Article -
7
Alternative splicing in the DBD linker region of p63 modulates binding to DNA and iASPP in vitro
Published 2025“…Here we characterize the interaction of iASPP with p63 and show that it binds to the linker region between the DNA binding domain and the oligomerization domain. …”
Journal article -
8
Regulation of mRNA abundance by polypyrimidine tract-binding protein-controlled alternate 5′ splice site choice
Published 2014“…Here we report that polypyrimidine tract-binding protein 1 (Ptbp1/PTB/hnRNP-I) controls alternate 5′ and 3′ splice site (5′ss and 3′ss) usage in a large set of mammalian transcripts. …”
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Journal Article -
9
The SARS-CoV-2 nucleocapsid protein interferes with the full enzymatic activation of UPF1 and its interaction with UPF2
Published 2025Journal article -
10
Mapping the structural and dynamical features of multiple p53 DNA binding domains : insights into loop 1 intrinsic dynamics
Published 2014“…The transcription factor p53 regulates cellular integrity in response to stress. p53 is mutated in more than half of cancerous cells, with a majority of the mutations localized to the DNA binding domain (DBD). …”
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Journal Article -
11
The novel quinoline derivative SKA-346 as a KCa3.1 channel selective activator
Published 2025“…In silico analysis using RosettaLigand and GLIDE demonstrated a well-converged pose of SKA-346 in a binding pocket at the interface between the calmodulin N-lobe and the S45A helix in the S4-S5 linker of the KCa3.1 channel. …”
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Journal Article -
12
Thick thrills: because life's too short for skinny taste
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Final Year Project (FYP) -
13
Broadcast Yourself via Digital Marketing: A Case Study of ‘Saiful Nang’ (S/O 14903)
Published 2022“…Since then, he never looks back, and the CSI flagpole is erected till it victory we feel now. This best practice company will expose the approaches of digital marketing that has been practised, digital skills and personal branding…”
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Monograph -
14
Macrobrachium rosenbergii De Man nodavirus recombinant capsid protein production and its interactions with RNA
Published 2015“…In 2012 the major farming areas in Malaysia were found to be infected by MrNv but till now information on the Malaysian isolate MrNv is still unavailable in the NCBI database and studies of this newly emerged member of the Nodaviridae family were not in depth. …”
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Thesis -
15
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16
Structural features that affect β2 integrin expression and regulation of adhesion
Published 2013“…In contrast, integrins with the β2-G150D mutation have no binding activities. LFA-1 with the β2-G716A mutation is constitutively active to bind ICAM-1 and requires only one activating agents to bind to ICAM-3. …”
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Thesis -
17
Structural study of plant cellulose synthase and atypical profilin3
Published 2020“…A low-resolution model of oligomeric full-length cellulose synthase was also obtained by Cryo-EM. …”
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Thesis-Doctor of Philosophy -
18
Different modes of regulation govern miRNA expression levels in Drosophila melanogaster
Published 2019“…Loquacious (Loqs) is a dsRNA-binding protein that binds Dicer-1 to cleave pre-miRNAs into short duplexes. …”
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Thesis-Doctor of Philosophy -
19
Part I Targeting RNA duplexes with modified triplex-forming oligonucleotides Part II Allostery within a Watson-Crick RNA duplex and its application in studying RNA recognition by R...
Published 2014“…Binding of full-length RIG-I and a triplex-forming oligonucleotide (TFO) also induces 2AP fluorescence enhancement. …”
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Thesis -
20
Protective Capacity of the Human Anamnestic Antibody Response during Acute Dengue Virus Infection
Published 2016“…Half of the world's population is exposed to the risk of dengue virus infection. …”
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Journal Article