Nanosized silica particles for achiral drug separation by Tan, Timothy Thatt Yang.

“…It is widely recognized that the full potential of rapid chromatography can be realized with very small support particulates and tailor-made chiral stationary phase. …”
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18F-labelling of new chemotypes for drug discovery by Khotavivattana, T

“…Finally, Chapter 5 gives full experimental procedures and characterisation data for all compounds.…”

Amplifying signals in the tumor microenvironment for drug development and diagnostics by Martin Alonso, Maria Carmen

“…Leveraging advancements in high throughput screening and in deep learning, we contribute important tools for the effective design of conditional drugs that require the cleavage of a protease substrate to unleash drug cytotoxicity. …”
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Functional genomics reveals an off-target dependency of drug synergy in gastric cancer therapy by Leylek, Ozen, Honeywell, Megan E., Lee, Michael J., Hemann, Michael T., Ozcan, Gulnihal

“…However, realizing the full potential of this approach requires a clear comprehension of the genetic dependencies underlying drug synergy. …”
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Controlled-release nanoencapsulating microcapsules to combat inflammatory diseases by Baek, Jong-Suep, Yeo, Eng Wan, Lee, Yin Hao, Tan, Nguan Soon, Loo, Say Chye Joachim

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Evaluation of paper spray mass spectrometry for direct analysis of small molecule drugs and hemoglobin constant spring peptide markers by Takyi-Williams, John

“…The studies described in this thesis were undertaken to evaluate the application of paper spray mass spectrometry for direct analysis of small molecule drugs and biomarker in dried matrix spot samples. …”
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SP.236 / ES.SP236 Exploring Pharmacology, Spring 2009 by Gusman, Mariya, Fallows, Zak

“…From Abilify to Zyrtec, the world is full of interesting drugs. Such substances have cured diseases, started wars, and ended careers. …”
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Modular Titratable Polypills for Personalized Medicine and Simplification of Complex Medication Regimens by Karavasili, Christina, Babaee, Sahab, Kutty, Shruti, Chu, Jacqueline N., Min, Seokkee, Fitzgerald, Nina, Morimoto, Joshua, Inverardi, Nicoletta, Traverso, Giovanni

“…To fill the existing gap in drug dose personalization and simplification of complex medication regimens commonly encountered in the treatment of cardiovascular disease, tuberculosis, and tapering of corticosteroid therapy, a modular titratable polypill approach that simultaneously addresses both aspects is proposed. …”
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An analysis of heavy silicone oil treatment for inferior proliferative vitreoretinopathy by Hammer, M, Ie, A, Eibenberger, K, Auffarth, GU, Xue, K

“…The number of glaucoma drugs were increased in 45% of patients during Densiron tamponade. …”

Mitochondrial dysfunction in Down Syndrome: from pathology to therapy by Tan, Kai-Leng, Lee, Han-Chung, Cheah, Pike-See, Ling, King-Hwa

“…Mitochondrial dysfunctions have been described in Down syndrome (DS) caused by either partial or full trisomy of chromosome 21 (HSA21). Mitochondria play a crucial role in various vital functions in eukaryotic cells, especially in energy production, calcium homeostasis and programmed cell death. …”
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Effect of metabolite and temperature on artificial human sweat characteristics over a very wide frequency range (400 MHz–10.4 GHz) for wireless hydration diagnostic sensors by Lubangakene, Innocent, Virdee, Bal Singh, Jayanthi, Renu, Ganguly, Priyanka

“…As a result, analysis of electrolytes in this biofluid is gaining traction in the development of non-invasive sweat diagnostics to determine level of dehydration, cystic fibrosis and illicit drugs. This paper presents a wireless measurement modality of permittivity properties of sweat of different metabolite concentration levels exemplifying the full spectrum of human sweat. …”
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Combined ultrasound and photoacoustic imaging of blood clot during microbubble-assisted sonothrombolysis by Das, Dhiman, Pramanik, Manojit

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The role of tumour necrosis factor alpha stimulated gene-6 on bone by Afrough, S

“…However, local delivery of full-length TSG-6 significantly enhanced mineral apposition rate in a dose-dependent manner, and <em>in vitro</em> studies found TSG-6 significantly enhanced alkaline phosphatase levels of primary bone marrow-derived human mesenchymal stem cells <em>in vitro</em>, in the presence of BMP-2.…”

Investigation of blood pressure regulation schemes by Chai, Chang Yong

“…Till date, there are a number of different types of blood pressure control systems designed and developed used for different blood pressure [5]. …”
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Interfacial phenomena and biological recognition of mammalian cells on biomimetic materials by Chan, Vincent.

“…We intend to fill this gap by interrogating the biophysical events involved in membrane-polymer interaction, biological adhesion, tissue engineering and cellular fluid mechanics. …”
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Duration of carbapenemase-producing enterobacteriaceae carriage in hospital patients by Mo, Yin, Hernandez-Koutoucheva, Anastasia, Musicha, Patrick, Bertrand, Denis, Lye, David C., Ng, Oon Tek, Fenlon, Shannon N., Chen, Swaine L., Ling, Moi Lin, Tang, Wen Ying, Barkham, Timothy, Nagarajan, Niranjan, Cooper, Ben S., Marimuthu, Kalisvar

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Ion doping behavior of stöber silica-nanosynthesis and application by Song, Xiaohui

“…Besides, we can dope positive charged organic molecules inside silica nanoparticle, such as dyes, drugs, and so on. The above synthesis control is important to silica application in biosensors, drug delivery, catalysts, and battery. …”
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Association of current Schistosoma mansoni, Schistosoma japonicum, and Schistosoma mekongi infection status and intensity with periportal fibrosis: a systematic review and meta-ana... by Ewuzie, A, Wilburn, L, Thakrar, DB, Cheng, H, Reitzug, F, Roberts, N, Malouf, R, Chami, GF

“…Two reviewers independently screened abstracts and full-text reports for eligibility. A third reviewer was consulted in cases of disagreement. …”

Optimising expression and purification of Dengue soluble E protein by Poh, Nina Yong Xin

“…It offers insights into viral-host immune interactions. The full-length E protein is essential for vaccine design. …”
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Investigation of Synthetic Proteins Produced via Automated Fast-Flow Peptide Synthesis by Cowfer, Amanda Elizabeth

“…I will discuss the iterative steps my team took to vary both chemical and mechanical and control variables to improve per-coupling yield enough to enable access to full-length single-domain proteins. On this journey, we utilized test peptides to validate synthesis quality and later synthesized a suite of full-length single-domain biologically active proteins. …”
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